Welcome to our dedicated page for RAPT Therapeutics news (Ticker: RAPT), a resource for investors and traders seeking the latest updates and insights on RAPT Therapeutics stock.
RAPT Therapeutics, Inc. (NASDAQ: RAPT) is a clinical-stage biopharmaceutical company specializing in immunology-based treatments. Focused on developing and commercializing oral small molecule therapies, RAPT Therapeutics aims to address significant unmet medical needs in oncology and inflammatory diseases. Utilizing its proprietary discovery and development engine, the company creates highly selective small molecules designed to modulate critical immune drivers underlying these conditions.
RAPT Therapeutics has two main drug candidates: FLX475 (tivumecirnon) and RPT193 (zelnecirnon). FLX475 targets the C-C motif chemokine receptor 4 (CCR4) and is designed to inhibit the migration of regulatory T cells into tumors, enhancing the immune response against cancer. RPT193, also targeting CCR4, focuses on inhibiting type 2 T helper cells in inflamed tissues, offering potential relief for inflammatory diseases like atopic dermatitis and asthma.
In recent developments, RAPT Therapeutics reported promising Phase 2 data for FLX475 in combination with pembrolizumab for non-small cell lung cancer (NSCLC) patients. The company also emphasized FLX475's potential in other cancers, including head and neck cancer, gastric cancer, and non-Hodgkin lymphoma. Despite a clinical hold placed by the FDA on the Phase 2 trials for zelnecirnon due to a serious adverse event, RAPT continues to investigate and aims to resolve the issue.
Financially, RAPT Therapeutics maintains a strong cash position, reporting $158.9 million in cash and equivalents by the end of 2023. The company is diligently working to advance its clinical programs and explore additional targets in the discovery stage, ensuring a robust pipeline for future developments.
RAPT Therapeutics, Inc. (Nasdaq: RAPT) has announced a $50 million private investment in public equity (PIPE) financing with the Redmile Group. The transaction involves pre-funded warrants for up to 4 million shares at $12.4999 each, based on the closing price on May 24, 2022. Gross proceeds are approximately $50 million before expenses, with closure expected by May 27, 2022. The company will file a registration statement to register the resale of these shares. This move supports RAPT's focus on developing oral small molecule therapies for inflammatory diseases and oncology.
RAPT Therapeutics has initiated a 16-week Phase 2b clinical trial for RPT193, an oral therapy aimed at treating moderate-to-severe atopic dermatitis (AD). This randomized, double-blind, placebo-controlled study will assess multiple doses of RPT193 and aims to confirm its efficacy and safety. Previous Phase 1b results indicated significant improvements in key efficacy measures and no serious adverse events. The trial's co-primary endpoints include the percent change in the Eczema Area and Severity Index (EASI) and the incidence of treatment-emergent adverse events.
RAPT Therapeutics, Inc. (Nasdaq: RAPT) reported Q1 2022 financial results, revealing a net loss of $20.5 million, up from $16.5 million in Q1 2021. Research and development expenses increased to $16.7 million due to clinical trial costs for RPT193 and FLX475. General and administrative expenses rose to $4.7 million. The company is advancing its clinical trials, including initiating a Phase 2b trial for RPT193 in atopic dermatitis and a Phase 2a trial for asthma. RAPT maintains a solid cash position of $173.0 million.
RAPT Therapeutics, Inc. (Nasdaq: RAPT) recently announced key leadership appointments, including Gwen Carscadden as Chief Human Resources Officer, Jim Farmer as Vice President of Clinical Operations, and Shari Geffon as Vice President of Program and Alliance Management. These hires are seen as pivotal in advancing RPT193 and FLX475 through clinical development. The company aims to address significant unmet needs in inflammatory diseases and oncology, leveraging the extensive experience of these new executives in their respective fields.
RAPT Therapeutics has reported promising biomarker data from its Phase 1b trial of RPT193 for moderate-to-severe atopic dermatitis, presented at the American Academy of Dermatology Annual Meeting. Key findings indicate a statistically significant improvement in the meta-analysis derived atopic dermatitis (MADAD) score (p<0.001) and positive changes in immune pathways linked to the disease. RAPT aims to initiate a Phase 2b clinical trial in atopic dermatitis, with plans to expand RPT193's development into asthma.
RAPT Therapeutics, Inc. reported its financial results for Q4 2021 and the full year, highlighting a net loss of $17.9 million for Q4 and $69.2 million for the year, an increase from $12.7 million and $52.9 million in 2020, respectively. R&D expenses rose to $14.3 million in Q4 and $57.0 million for the year due to clinical trial costs for RPT193 and FLX475. General and administrative expenses also increased to $4.5 million in Q4 and $16.0 million for the year. The company maintained a robust cash position of $189.7 million as of year-end.
SOUTH SAN FRANCISCO, Calif., Feb. 09, 2022 – RAPT Therapeutics, a clinical-stage biopharmaceutical company, announced that Brian Wong, M.D., Ph.D., President and CEO, will participate in a virtual fireside chat at the 11th Annual SVB Leerink Healthcare Conference on February 16, 2022, at 1:40 p.m. ET. The event will discuss the company's focus on developing oral small molecule therapies for inflammatory diseases and oncology. Interested parties can access the live or archived webcast on the RAPT Therapeutics website.
SOUTH SAN FRANCISCO, Calif., Jan. 04, 2022 – RAPT Therapeutics, Inc. (Nasdaq: RAPT), a clinical-stage biopharmaceutical company, announced that President and CEO Brian Wong, M.D., Ph.D., will present at the 40th Annual J.P. Morgan Healthcare Conference. The event will take place on January 11, 2022, at 9:00 a.m. ET. RAPT focuses on developing oral small molecule therapies for inflammatory diseases and oncology. The company has advanced drug candidates RPT193 and FLX475, targeting CCR4 for treating inflammation and cancer. Access the presentation via the RAPT website.
RAPT Therapeutics reported a net loss of $18.7 million for Q3 2021, up from $14.6 million in Q3 2020. Research and development expenses rose to $15.7 million due to clinical trial costs for FLX475 and RPT193. Total net loss for the nine months ended September 30, 2021, was $51.3 million, compared to $40.2 million in the prior year. RAPT aims to advance RPT193 into Phase 2 trials in 2022 and is focusing on FLX475 for various cancers, with data updates expected at a medical meeting in 2022. The company holds $210.8 million in cash and securities.
RAPT Therapeutics, a clinical-stage biopharmaceutical company, has appointed Lori Lyons-Williams to its Board of Directors. With over 20 years of experience, she previously held key roles at Neumora Therapeutics and Dermira, driving strategic success in biotechnology. Her expertise is expected to significantly benefit RAPT's inflammation and oncology product pipeline, particularly RPT193. RAPT develops oral small molecule therapies for patients with severe unmet needs, focusing on inflammatory diseases and cancer.
FAQ
What is the current stock price of RAPT Therapeutics (RAPT)?
What is the market cap of RAPT Therapeutics (RAPT)?
What does RAPT Therapeutics do?
What are the main drug candidates of RAPT Therapeutics?
What recent achievements has RAPT Therapeutics made?
What financial condition is RAPT Therapeutics in?
What is FLX475?
What is RPT193?
What is the status of the Phase 2 trials for zelnecirnon?
What recent financial results has RAPT Therapeutics reported?
How is RAPT Therapeutics funded for its ongoing operations?
What are the primary focuses of RAPT Therapeutics' research?
