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Rapt Therapeutics, Inc. - RAPT STOCK NEWS

Welcome to our dedicated page for Rapt Therapeutics news (Ticker: RAPT), a resource for investors and traders seeking the latest updates and insights on Rapt Therapeutics stock.

Company Overview

RAPT Therapeutics, Inc. is a clinical-stage immunology-based biopharmaceutical company focused on the discovery, development, and commercialization of oral small molecule therapies. Leveraging its proprietary discovery and development engine, the company is addressing significant unmet needs in both oncology and inflammatory diseases with a focus on modulating key immune drivers.

Core Business and Clinical Strategy

The company operates at the intersection of immunology and precision medicine, and is dedicated to the development of highly selective small molecules. Its innovative approach is centered on targeting the C-C motif chemokine receptor 4 (CCR4), a pivotal immune pathway implicated in the regulation of immune cell migration. By impeding the movement of regulatory T cells and type 2 T helper cells, RAPT aims to normalize immune responses in both cancer and inflammatory contexts.

Pipeline and Drug Candidates

RAPT Therapeutics has advanced multiple drug candidates through its development pipeline. Key assets include:

  • Tivumecirnon (FLX475): Designed to block the migration of regulatory T cells into tumors, potentially enhancing anti-tumor immune responses.
  • Zelnecirnon (RPT193): Engineered to inhibit the migration of specific T cell subsets into inflamed tissues, targeting inflammatory diseases.
  • RPT904: A clinical-stage anti-immunoglobulin E (IgE) antibody developed under a global licensing arrangement to address allergic disorders such as food allergy and chronic spontaneous urticaria.

Each candidate is a testament to the company’s commitment to precision pharmacology and medicinal chemistry, aiming to provide tailored therapeutic solutions while maintaining a robust platform for early-stage target discovery.

Research, Development, and Clinical Insights

Utilizing deep expertise in immunology, RAPT integrates rigorous scientific evaluation with methodical clinical development. Its research programs are designed to modulate immune responses by directly targeting critical pathways, and the company has steadily progressed in a highly competitive landscape. The strategic clinical trials encompass both monotherapy and combination approaches, allowing the company to assess therapeutic synergies and optimize clinical outcomes.

Competitive Positioning and Intellectual Rigor

Within the biopharmaceutical arena, RAPT stands apart by focusing on the modulation of immune cell migration. This strategy is particularly significant given the limitations of existing therapies in oncology and inflammatory conditions. The company’s methodical approach, which combines a proprietary discovery engine with precise clinical execution, establishes it as an informed participant in the competitive biotech sector. Its strategic partnerships and licensing deals further reinforce its commitment to diversifying and strengthening its therapeutic portfolio.

Business Model and Market Impact

The business model is built on robust R&D investment, strategic collaborations, and a well-structured pipeline aimed at delivering high specificity treatments. Investors can note the company’s methodical transition from early clinical trials to confirmation of pharmacodynamic effects, which supports its long-term mission to address critical immune-mediated conditions. RAPT Therapeutics represents a specialized venture into areas where there is a significant unmet need, thereby setting the stage for potential market differentiation through scientifically driven innovation.

Summary

RAPT Therapeutics is not just advancing a series of drug candidates; it is pioneering a targeted approach in the realm of immunology. Its clear focus on modulating specific immune mechanisms and its strategic clinical development make the company a subject of continued interest in the biopharmaceutical investment landscape. Through precise, selective targeting and rigorous clinical evaluation, RAPT demonstrates deep domain expertise and a commitment to addressing complex medical challenges.

Rhea-AI Summary

RAPT Therapeutics reported a net loss of $18.7 million for Q3 2021, up from $14.6 million in Q3 2020. Research and development expenses rose to $15.7 million due to clinical trial costs for FLX475 and RPT193. Total net loss for the nine months ended September 30, 2021, was $51.3 million, compared to $40.2 million in the prior year. RAPT aims to advance RPT193 into Phase 2 trials in 2022 and is focusing on FLX475 for various cancers, with data updates expected at a medical meeting in 2022. The company holds $210.8 million in cash and securities.

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RAPT Therapeutics, a clinical-stage biopharmaceutical company, has appointed Lori Lyons-Williams to its Board of Directors. With over 20 years of experience, she previously held key roles at Neumora Therapeutics and Dermira, driving strategic success in biotechnology. Her expertise is expected to significantly benefit RAPT's inflammation and oncology product pipeline, particularly RPT193. RAPT develops oral small molecule therapies for patients with severe unmet needs, focusing on inflammatory diseases and cancer.

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RAPT Therapeutics, based in South San Francisco, announced that CEO Brian Wong will present at key investor conferences in November 2021. These include the Stifel 2021 Virtual Healthcare Conference on November 15 at 2:00 p.m. ET and the Piper Sandler 33rd Annual Virtual Healthcare Conference on November 22 available on-demand at 10:00 a.m. ET. RAPT Therapeutics focuses on developing oral small molecule therapies for inflammatory diseases and oncology, with drug candidates like RPT193 and FLX475 targeting CCR4.

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RAPT Therapeutics, Inc. (Nasdaq: RAPT) announced the presentation of clinical efficacy data from its Phase 1b trial of RPT193, an oral CCR4 inhibitor for moderate-to-severe atopic dermatitis. The presentation will occur at the 4th Inflammatory Skin Disease Summit in New York, from November 3-6, 2021. The trial is designed to demonstrate the efficacy of RPT193 compared to a placebo. This is part of RAPT's commitment to developing therapies for significant unmet needs in oncology and inflammatory diseases.

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RAPT Therapeutics announced positive topline results from its Phase 1b clinical trial of RPT193 for moderate-to-severe atopic dermatitis, presented at the EADV Congress. The trial demonstrated significant efficacy across key exploratory endpoints including EASI and vIGA, with benefits observed persisting two weeks post-treatment. RPT193 was well tolerated, showing a clean safety profile with no serious adverse events. The company plans to advance RPT193 to a Phase 2b trial in atopic dermatitis and a Phase 2a trial in asthma, highlighting its potential in treating inflammatory diseases.

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RAPT Therapeutics, a clinical-stage biopharmaceutical company, announced that CEO Brian Wong will present at the 2021 Cantor Virtual Healthcare Conference on September 27, 2021, at 2:00 p.m. EST. The company focuses on developing oral small molecule therapies for unmet needs in oncology and inflammatory diseases, with two drug candidates, FLX475 and RPT193, targeting CCR4 receptors. For access to the live webcast and archived recordings, visit the RAPT Therapeutics website.

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RAPT Therapeutics announced it will present clinical safety and efficacy data for RPT193, an oral CCR4 inhibitor, from its Phase 1b trial targeting moderate-to-severe atopic dermatitis at the upcoming 30th European Academy of Dermatology and Venereology Congress on September 30, 2021. The presentation highlights a significant step in RAPT's ongoing commitment to develop novel therapies for unmet needs in oncology and inflammatory diseases.

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SOUTH SAN FRANCISCO, Calif., Sept. 3, 2021 – RAPT Therapeutics (Nasdaq: RAPT) announced that Brian Wong, M.D., Ph.D., President and CEO, will present at key investor conferences in September. Notably, he will speak at the Wells Fargo 2021 Virtual Healthcare Conference on September 9 at 8:00 a.m. EST and the H.C. Wainwright 23rd Annual Global Investment Conference on September 13 at 7:00 a.m. EST. For live webcasts and archived recordings, visit RAPT's official website. RAPT focuses on oral therapies for oncology and inflammatory diseases, advancing drug candidates targeting CCR4.

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RAPT Therapeutics reported Q2 2021 financial results, highlighting a net loss of $16.1 million, up from $12.4 million year-over-year. R&D expenses rose to $13.2 million, driven by clinical trial costs for FLX475. The company successfully completed a public offering, generating $134.6 million, enhancing its cash position to $223.3 million. Notable achievements include positive topline results from the Phase 1b trial of RPT193 for atopic dermatitis. RAPT remains optimistic about advancing its drug development initiatives in oncology and inflammatory diseases.

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RAPT Therapeutics has successfully closed its underwritten public offering of 4,356,060 shares of common stock at $33.00 per share, raising approximately $143.7 million before expenses. This includes 568,181 shares sold due to underwriters' full exercise of their option. The offering was made under an effective shelf registration statement filed with the SEC. J.P. Morgan, SVB Leerink, and Piper Sandler acted as joint lead book-running managers for this offering.

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FAQ

What is the current stock price of Rapt Therapeutics (RAPT)?

The current stock price of Rapt Therapeutics (RAPT) is $1.06 as of April 4, 2025.

What is the market cap of Rapt Therapeutics (RAPT)?

The market cap of Rapt Therapeutics (RAPT) is approximately 144.5M.

What is the primary focus of RAPT Therapeutics, Inc.?

RAPT Therapeutics primarily focuses on discovering, developing, and commercializing oral small molecule therapies to address unmet needs in oncology and inflammatory diseases.

How does RAPT Therapeutics generate its drug candidates?

The company utilizes a proprietary discovery and development engine to create highly selective small molecules that modulate key immune drivers, particularly targeting the CCR4 pathway.

Which therapeutic areas does RAPT address?

RAPT addresses critical challenges in oncology by inhibiting tumor immune suppression, and in inflammatory diseases by modulating immune cell migration into inflamed tissues.

What distinguishes RAPT’s approach to drug development?

RAPT’s approach is distinguished by its focus on precision immunology, selective targeting of immune pathways, and a strategy that integrates both monotherapy and combination therapy clinical trials.

Can you explain the significance of the CCR4 target in their pipeline?

CCR4 plays a key role in regulating immune cell migration. By targeting this receptor, RAPT aims to prevent the infiltration of cells that suppress immune responses in cancer or exacerbate inflammation in chronic diseases.

What are some of the key drug candidates in RAPT's pipeline?

Key drug candidates include tivumecirnon (FLX475) for oncology, zelnecirnon (RPT193) for inflammatory conditions, and RPT904 which is aimed at allergic conditions such as food allergy and chronic spontaneous urticaria.

How does RAPT Therapeutics position itself within the competitive biopharmaceutical landscape?

RAPT is positioned as a specialized enterprise that applies targeted immunotherapy approaches. Its proprietary platform and strategic clinical development efforts underpin its competitive differentiation in areas of high unmet need.

What type of clinical trials does the company undertake?

The company conducts a range of clinical trials, including Phase 1/2 studies that integrate both monotherapy and combination regimens, aimed at evaluating safety, pharmacodynamics, and efficacy across various cancer and inflammatory disease indications.
Rapt Therapeutics, Inc.

Nasdaq:RAPT

RAPT Rankings

RAPT Stock Data

144.55M
99.83M
0.49%
96.43%
1.99%
Biotechnology
Pharmaceutical Preparations
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United States
SOUTH SAN FRANCISCO