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Clarivate Introduces New OFF-X ™ Platform for Preclinical and Clinical Safety Intelligence

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Clarivate Plc (NYSE:CLVT) has launched the new OFF-X™ platform, an enhanced solution for preclinical and clinical safety intelligence in biopharma. The platform offers a seamless user experience and unique translational insights, delivering important drug and target safety intelligence to proactively identify risks. Fully integrated with Cortellis Drug Discovery Intelligence™, OFF-X™ provides a comprehensive resource for safety information, streamlining processes and enhancing efficiency.

Key improvements include an 80% reduction in loading times for targets, drugs, drug combinations, and adverse events, faster search capabilities, clearer visual design, full-screen visualization, and additional analytic tools. The platform empowers users to monitor and anticipate toxicology and safety signals, mitigate safety liabilities, and de-risk assets across all phases of drug R&D and post-marketing.

Clarivate Plc (NYSE:CLVT) ha lanciato la nuova piattaforma OFF-X™, una soluzione avanzata per l'intelligenza sulla sicurezza preclinica e clinica nel settore biopharma. La piattaforma offre un esperienza utente senza soluzione di continuità e intuizioni traslazionali uniche, fornendo informazioni cruciali sulla sicurezza di farmaci e obiettivi per identificare proattivamente i rischi. Completamente integrata con Cortellis Drug Discovery Intelligence™, OFF-X™ rappresenta una risorsa completa per le informazioni sulla sicurezza, rendendo più snelli i processi e migliorando l'efficienza.

I principali miglioramenti includono una riduzione dell'80% dei tempi di caricamento per obiettivi, farmaci, combinazioni di farmaci e eventi avversi, capacità di ricerca più rapide, design visivo più chiaro, visualizzazione a schermo intero e strumenti analitici aggiuntivi. La piattaforma consente agli utenti di monitorare e anticipare segnali di tossicologia e sicurezza, mitigare le responsabilità legate alla sicurezza e ridurre i rischi sui beni in tutte le fasi della R&S dei farmaci e post-marketing.

Clarivate Plc (NYSE:CLVT) ha lanzado la nueva plataforma OFF-X™, una solución mejorada para la inteligencia de seguridad preclínica y clínica en biopharma. La plataforma ofrece una experiencia de usuario fluida y perspectivas translacionales únicas, proporcionando información importante sobre la seguridad de medicamentos y objetivos para identificar proactivamente riesgos. Totalmente integrada con Cortellis Drug Discovery Intelligence™, OFF-X™ proporciona un recurso integral para la información de seguridad, optimizando procesos y mejorando la eficiencia.

Las mejoras clave incluyen una reducción del 80% en los tiempos de carga para objetivos, medicamentos, combinaciones de medicamentos y eventos adversos, capacidades de búsqueda más rápidas, un diseño visual más claro, visualización en pantalla completa y herramientas analíticas adicionales. La plataforma capacita a los usuarios para monitorear y anticipar señales de toxicología y seguridad, mitigar responsabilidades de seguridad y reducir riesgos en todos los fases de I+D de medicamentos y post-comercialización.

Clarivate Plc (NYSE:CLVT)는 생명공학 분야에서 전임상 및 임상 안전 정보에 대한 향상된 솔루션인 새로운 OFF-X™ 플랫폼을 출시했습니다. 이 플랫폼은 매끄러운 사용자 경험과 독특한 전이 통찰력을 제공하여, 약물 및 대상의 안전 정보를 통해 리스크를 사전에 식별할 수 있도록 합니다. Cortellis Drug Discovery Intelligence™와 완전히 통합된 OFF-X™는 안전 정보에 대한 포괄적인 자원을 제공하여, 프로세스를 간소화하고 효율성을 높입니다.

주요 개선 사항으로는 대상, 약물, 약물 조합 및 부작용에 대한 로드 시간 80% 단축, 더 빠른 검색 기능, 더 명확한 시각 디자인, 전체 화면 시각화, 추가 분석 도구 등이 있습니다. 이 플랫폼은 사용자가 독성학 및 안전 신호를 모니터링하고 예측하며, 안전 책임을 완화하고 자산을 다양한 약물 연구 개발 및 판매 후 모든 단계에서 리스크를 줄일 수 있도록 돕습니다.

Clarivate Plc (NYSE:CLVT) a lancé la nouvelle plateforme OFF-X™, une solution améliorée pour l'intelligence de sécurité préclinique et clinique dans le secteur biopharmaceutique. La plateforme offre une expérience utilisateur fluide et des aperçus translationnels uniques, fournissant des informations importantes sur la sécurité des médicaments et des cibles pour identifier proactivement les risques. Entièrement intégrée à Cortellis Drug Discovery Intelligence™, OFF-X™ constitue une ressource complète pour les informations de sécurité, rationalisant les processus et améliorant l'efficacité.

Parmi les améliorations clés figurent une réduction de 80 % des temps de chargement pour les cibles, les médicaments, les combinaisons de médicaments et les événements indésirables, des capacités de recherche plus rapides, un design visuel plus clair, une visualisation en plein écran et des outils analytiques supplémentaires. La plateforme permet aux utilisateurs de surveiller et d'anticiper les signaux de toxicologie et de sécurité, de réduire les responsabilités en matière de sécurité et de diminuer les risques liés aux actifs à toutes les phases de la R&D des médicaments et après commercialisation.

Clarivate Plc (NYSE:CLVT) hat die neue OFF-X™ Plattform eingeführt, eine verbesserte Lösung für präklinische und klinische Sicherheitsinformationen in der Biopharma-Branche. Die Plattform bietet ein nahtloses Benutzererlebnis und einzigartige translationale Einblicke, die wichtige Sicherheitsinformationen zu Medikamenten und Zielen liefern, um Risiken proaktiv zu identifizieren. Vollständig integriert mit Cortellis Drug Discovery Intelligence™, bietet OFF-X™ eine umfassende Ressource für Sicherheitsinformationen, die Prozesse optimiert und die Effizienz steigert.

Zu den wichtigsten Verbesserungen gehören eine 80%ige Reduzierung der Ladezeiten für Ziele, Medikamente, Arzneimittelkombinationen und unerwünschte Ereignisse, schnellere Suchfähigkeiten, ein klareres visuelles Design, eine Vollbildvisualisierung und zusätzliche Analysetools. Die Plattform ermöglicht es den Benutzern, toxikologische und Sicherheitsalarme zu überwachen und vorherzusagen, Sicherheitsverpflichtungen zu mindern und Risiken in allen Phasen der Arzneimittelforschung und -entwicklung sowie nach der Markteinführung zu reduzieren.

Positive
  • Launch of enhanced OFF-X™ platform for improved safety intelligence
  • 80% reduction in loading times for key data
  • Integration with Cortellis Drug Discovery Intelligence™ for comprehensive safety information
  • Enhanced functionality including faster search and additional analytic tools
Negative
  • None.

Insights

Clarivate's launch of the new OFF-X™ platform marks a significant advancement in preclinical and clinical safety intelligence for the biopharma industry. The platform's integration with Cortellis Drug Discovery Intelligence™ creates a powerful, unified resource for comprehensive safety information.

Key technical improvements include:

  • An 80% reduction in loading times for critical data points such as targets, drugs, drug combinations and adverse events.
  • Enhanced search capabilities for faster data retrieval.
  • Improved visual design for better user experience.
  • Full-screen visualization options for detailed data analysis.
  • Additional analytic tools to derive deeper insights.

These enhancements collectively contribute to a more efficient and user-friendly experience, potentially saving valuable time in drug development processes. The platform's ability to provide translational insights could be particularly valuable in bridging the gap between preclinical and clinical stages, a critical point where many drug candidates fail.

From a technological standpoint, the mention of an 'upgraded technology stack' suggests Clarivate has likely implemented more modern, scalable technologies. This could improve the platform's performance, reliability and ability to handle large datasets - important factors in the data-intensive field of drug safety analysis.

While the platform shows promise, it's important to note that its effectiveness will ultimately depend on the quality and comprehensiveness of the underlying data, as well as the sophistication of its analytical algorithms. The true value of these technological improvements will be realized as users integrate the platform into their workflows and assess its impact on decision-making processes in drug development.

The introduction of Clarivate's enhanced OFF-X™ platform represents a significant development in the realm of drug safety intelligence. This tool has the potential to substantially impact the drug development process, particularly in the critical areas of risk assessment and mitigation.

Key benefits for medical research include:

  • Proactive identification of safety risks across all phases of drug R&D and post-marketing.
  • Comprehensive monitoring of toxicology and safety signals.
  • Enhanced ability to mitigate safety liabilities and de-risk assets.
  • Streamlined access to important safety information.

The platform's integration with Cortellis Drug Discovery Intelligence™ is particularly noteworthy. This combination creates a unified resource that could significantly reduce the time researchers spend searching for and compiling safety data from disparate sources.

The 80% reduction in loading times for targets, drugs, drug combinations and adverse events is a substantial improvement. In the fast-paced world of drug development, this speed increase could translate to more efficient decision-making processes and potentially faster progression through development stages.

However, it's important to remember that while such platforms can greatly assist in identifying potential risks, they cannot replace the need for rigorous clinical trials and expert interpretation of data. The true value of OFF-X™ will be determined by its ability to accurately predict and help mitigate real-world safety issues in drug development.

Ultimately, if the platform delivers on its promises, it could contribute to more informed decision-making in drug development, potentially leading to safer drugs reaching patients more quickly and efficiently. This could have far-reaching implications for both the pharmaceutical industry and public health.

Empowering biopharma with enhanced safety insights to anticipate risks and unlock new competitive advantages

LONDON, July 30, 2024 /PRNewswire/ -- Clarivate Plc (NYSE:CLVT) a leading global provider of transformative intelligence, today announced the launch of the new OFF-X™ platform. The enhanced solution offers a seamless user experience and unique translational insights. It delivers crucial drug and target safety intelligence to proactively identify risks. Fully integrated with Cortellis Drug Discovery Intelligence™, OFF-X™ provides a comprehensive, one-stop resource for safety information, streamlining processes and enhancing efficiency which ultimately delivers a competitive edge.

The new platform features an upgraded technology stack and enhanced functionality while retaining its core capabilities. These improvements include an 80% reduction in loading times for targets, drugs, drug combinations and adverse events. The platform now offers faster search capabilities, a clearer visual design, full-screen visualization and additional analytic tools.

Justin Hubbard, Vice President, Product Management, Life Sciences and Healthcare at Clarivate, said:  "The launch of the new OFF-X™ platform underscores our dedication to providing actionable, comprehensive solutions in life sciences and healthcare. OFF-X revolutionizes access to safety information across all drug R&D and post-marketing phases, with speed and customization. By combining our safety intelligence with advanced analytics, we empower clients to accelerate the delivery of safe, effective and commercially successful treatments to patients."

OFF-X empowers users to monitor and anticipate toxicology and safety signals, mitigate safety liabilities and de-risk assets across all phases of drug R&D and post-marketing, bolstering confident development and investment decisions.

Learn more about OFF-X here.

About OFF-X™

OFF-X is the new translational safety intelligence platform that facilitates integrated preclinical toxicity data, clinical and pharmacovigilance adverse event data, visualizations and preclinical safety analytics. Updated daily, the platform incorporates wide-ranging analytics and visualizations, as well as comprehensive range of safety information sources and datasets, including a range of over 15,000 targets and more than 39,000 drugs & biologics, populated with almost 3 million expertly curated safety alerts associated to 14,000 adverse events and toxicity endpoints.

About Clarivate
Clarivate™ is a leading global provider of transformative intelligence. We offer enriched data, insights & analytics, workflow solutions and expert services in the areas of Academia & Government, Intellectual Property and Life Sciences & Healthcare. For more information, please visit www.clarivate.com

Media Contact:
Luna Ivkovic,
External Communications, Life Sciences & Healthcare
newsroom@clarivate.com

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SOURCE Clarivate Plc

FAQ

What is the new OFF-X™ platform launched by Clarivate (CLVT)?

The new OFF-X™ platform is an enhanced solution for preclinical and clinical safety intelligence in biopharma, offering a seamless user experience and unique translational insights to proactively identify risks in drug development.

How does the new OFF-X™ platform improve efficiency for Clarivate (CLVT) users?

The platform offers an 80% reduction in loading times for targets, drugs, drug combinations, and adverse events, faster search capabilities, clearer visual design, and additional analytic tools, streamlining processes and enhancing efficiency.

What are the key benefits of Clarivate's (CLVT) new OFF-X™ platform for drug development?

OFF-X™ empowers users to monitor and anticipate toxicology and safety signals, mitigate safety liabilities, and de-risk assets across all phases of drug R&D and post-marketing, supporting confident development and investment decisions.

How does Clarivate's (CLVT) OFF-X™ platform integrate with other solutions?

OFF-X™ is fully integrated with Cortellis Drug Discovery Intelligence™, providing a comprehensive, one-stop resource for safety information in drug development and research.

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