Welcome to our dedicated page for Annovis Bio news (Ticker: ANVS), a resource for investors and traders seeking the latest updates and insights on Annovis Bio stock.
Annovis Bio, Inc. (NYSE: ANVS) generates a steady flow of news as a late-stage clinical drug platform company focused on neurodegenerative diseases such as Alzheimer’s disease (AD) and Parkinson’s disease (PD). This news page aggregates announcements that reflect the company’s progress in clinical development, regulatory interactions, scientific presentations, and corporate activity.
Readers can follow updates on buntanetap, Annovis’ lead drug candidate, across multiple indications. News items include milestones from the pivotal Phase 3 trial in early Alzheimer’s disease, such as activation of clinical sites, enrollment status, and timing of key readouts. In Parkinson’s disease, press releases cover Phase 3 data analyses, biomarker findings related to amyloid co‑pathology and tau measures, and the design and objectives of the Open-Label Extension study that evaluates long-term safety and efficacy in diverse patient cohorts, including those receiving deep brain stimulation.
Company news also highlights regulatory developments, including scheduled FDA meetings to discuss the pathway for Parkinson’s disease dementia and confirmation of alignment on Phase 3 Alzheimer’s study design and endpoints. Scientific communications feature presentations at major conferences focused on Parkinson’s disease and Alzheimer’s clinical trials, where Annovis shares biomarker data, cross-study comparisons, and analyses of cognitive outcomes in patients with defined biomarker profiles.
In addition to clinical and scientific updates, this feed includes corporate events such as earnings releases, capital raises through registered direct offerings, leadership changes, and NYSE listing compliance disclosures. Investors, clinicians, and other stakeholders can use this page to track how Annovis communicates its trial progress, financial condition, and strategic priorities over time. For those following ANVS stock or the development of buntanetap in Alzheimer’s and Parkinson’s disease, this news stream provides a consolidated view of the company’s publicly reported milestones.
Annovis (NYSE: ANVS) announced issuance of U.S. Patent No. 12,582,632 B2 for buntanetap covering prevention and treatment of neurological injuries caused by brain infections. The patent covers administration across viral, bacterial, fungal, protozoan and parasitic agents, includes preventive and reversal claims, and extends through 2044.
The company is a Phase 3 clinical-stage developer of buntanetap for neurodegenerative diseases.
Annovis (NYSE: ANVS) announced publication of a historical review of its lead candidate buntanetap in The Scientist on March 31, 2026. The article traces buntanetap's discovery, chemical refinement and clinical progress, and places its development in scientific and historical context.
Clinical status: pivotal Phase 3 in early AD (NCT06709014) is 70% enrolled; PD open‑label extension (NCT07284784) is 20% enrolled.
Annovis Bio (NYSE: ANVS) partnered with NeuroRPM to deploy an FDA-cleared AI digital biomarker platform in its open-label Parkinson’s study (ANVS-25002), a 36-month, 25-site U.S. trial testing buntanetap. The study has enrolled 90 of an estimated 500 patients and combines wearable symptom monitoring with a skin-based alpha-synuclein assay reporting >90% sensitivity and specificity.
The initiative aims to capture real-world, continuous measures of bradykinesia, tremor and dyskinesia and link digital and biological biomarkers to better track treatment response and inform future trial design.
Annovis (NYSE: ANVS) reported fiscal 2025 results and corporate updates focused on clinical progress for buntanetap. Key points: initiation of a pivotal Phase 3 AD trial, 65% enrollment across 83 U.S. sites, an OLE PD study launched, patent protection extended to 2047, and year‑end cash of $19.5M.
Financials: R&D $25.2M, G&A $4.5M, net loss per share $1.40 on 20.6M weighted shares; 27.2M shares outstanding. Cash expected to fund operations into Q3 2026.
Annovis (NYSE: ANVS) announced two presentations at AD/PD™ 2026 in Copenhagen, March 17-21, 2026, covering clinical data for buntanetap in Parkinson’s disease and an update on the pivotal Phase 3 trial in early Alzheimer’s disease.
Presenters and session IDs: Presentation #3581 on PD cognition/biomarkers and Presentation #3582 on a 6- and 18-month randomized Phase 3 trial in early AD, both presented by Cheng Fang, Ph.D.
Annovis Bio (NYSE: ANVS) announced that an independent DSMB issued a positive safety recommendation for 6-month buntanetap data, allowing the pivotal Phase 3 Alzheimer's trial to continue without modification.
The DSMB found no safety concerns, noted alignment with Parkinson's safety data, the trial is 40% enrolled, and key readouts are expected early 2027 (symptomatic) and early 2028 (disease‑modifying).
Annovis (NYSE: ANVS) will begin an Open-Label Extension (OLE) study for Parkinson's disease in January 2026 to evaluate long-term safety and efficacy of buntanetap.
Key design: enrollment target 500 patients across U.S. sites, 36-month once-daily 30 mg treatment, two cohorts (invited former study participants and patients with deep brain stimulation). Skin and plasma biomarkers will be collected.
The OLE is intended to help meet FDA patient-exposure criteria toward NDA readiness by contributing to a ~1,500 treated-patient target and required multi-duration exposure thresholds.
Annovis (NYSE: ANVS) will host a corporate update webinar on January 28, 2026 at 4:30 p.m. ET featuring President and CEO Maria Maccecchini, Ph.D.. The presentation will review the company’s recent progress, ongoing late‑stage clinical programs in Alzheimer’s and Parkinson’s disease, strategic direction, and upcoming early‑2026 milestones, followed by a live Q&A.
The webinar is open to shareholders, patients, investigators, and other interested parties; participants are encouraged to register via the company registration link and may submit questions in advance to ir@annovisbio.com.
Annovis (NYSE: ANVS) will present at the 2025 Annual Meeting of the Parkinson Study Group in San Diego, Dec 4-6, 2025.
The company will present Phase 3 Parkinson's disease biomarker data showing that patients with amyloid co-pathology experienced greater cognitive decline that was counteracted and reversed by buntanetap; buntanetap also reduced tau biomarkers. The poster includes a cross-study comparison of completed trials and highlights that patients with amyloid pathology show the largest cognitive gains.
Presentation: Amyloid co-pathology, cognitive decline, and improvement in buntanetap-treated Parkinson’s disease dementia patients by Maria Maccecchini, Ph.D., on Dec 5 at 6:15 p.m. PST; data will be posted on the company website after the meeting.
Annovis (NYSE: ANVS) announced two scientific presentations at the 18th Clinical Trials on Alzheimer’s Disease (CTAD), December 1–4, 2025 in San Diego.
Presentation P073 covers amyloid co-pathology and cognitive decline in buntanetap-treated Parkinson’s disease dementia patients, presented by Cheng Fang, Ph.D. Presentation P007 describes a double 6/18-month Phase 3 study testing symptomatic and potential disease‑modifying efficacy of buntanetap in Alzheimer’s disease, presented by Maria Maccecchini, Ph.D., President and CEO. Both talks highlight recent biomarker data and cognition findings the company says support buntanetap’s potential disease‑modifying activity.