| UNITED STATES |
| SECURITIES AND EXCHANGE COMMISSION |
| Washington, D.C. 20549 |
| Notice of Effectiveness |
| Effectiveness Date: |
March 26,
2026 |
| Accession Number: |
0001193125-26-124474 |
| Submission Type: |
POS AM |
| CIK: |
0001327273 |
| Company Name: |
Lyra Therapeutics, Inc. |
| File Number: |
333-278163 |
|
