CLNN Form 4: 2,887 stock options granted at $7.30, immediate vest

Rhea-AI Filing Summary

Clene Inc. (CLNN) reported an insider equity award. A director filed a Form 4 disclosing a stock option grant for 2,887 shares of common stock at an exercise price of $7.30 per share on November 13, 2025. The options vest immediately upon grant under the Clene Inc. Amended 2020 Stock Plan and carry an expiration date of November 12, 2035. Following the transaction, the filing shows 2,887 derivative securities beneficially owned with direct ownership.

Insider Trade Summary

1 transaction reported

Mixed 1 txn

Insider Mosca Alison

Role Director

Type	Security	Shares	Price	Value
Grant/Award	stock option	2,887	$0.00	--

Holdings After Transaction: stock option — 2,887 shares (Direct)

Footnotes (1)

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Form 4 Insider Transactions: What Each Field Means →

SEC Form 4

FORM 4

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940

OMB APPROVAL

OMB Number:			3235-0287
Estimated average burden
hours per response:			0.5

Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.

1. Name and Address of Reporting Person^*

Mosca Alison

(Last) (First) (Middle)

6550 SOUTH MILLROCK DRIVE

SUITE G50

(Street)

SALT LAKE CITY UT 84121

(City) (State) (Zip)

2. Issuer Name and Ticker or Trading Symbol
Clene Inc. [ CLNN ]

5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)

X	Director		10% Owner
	Officer (give title below)		Other (specify below)

3. Date of Earliest Transaction (Month/Day/Year)
11/13/2025

4. If Amendment, Date of Original Filed (Month/Day/Year)

6. Individual or Joint/Group Filing (Check Applicable Line)

X	Form filed by One Reporting Person
	Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any (Month/Day/Year)	3. Transaction Code (Instr. 8)		4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5)			5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4)	6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
			Code	V	Amount	(A) or (D)	Price

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	4. Transaction Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date (Month/Day/Year)		7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
				Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares
stock option	$7.3	11/13/2025		A		2,887		(1)	11/12/2035	common stock	2,887	$0	2,887	D

Explanation of Responses:

1. This option was granted on November 13, 2025 as an option for 2,887 shares of Common Stock under the Clene Inc. Amended 2020 Stock Plan at an exercise price of $7.30 per share. The options vest immediately upon grant.

	/s/ Jerome T. Miraglia POA	11/14/2025
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.

FAQ

What did Clene (CLNN) disclose in this Form 4?

A director received a stock option for 2,887 shares at an exercise price of $7.30 per share granted on November 13, 2025.

When do the Clene (CLNN) options vest?

The options vest immediately upon grant.

What is the expiration date of the options reported by CLNN?

The options expire on November 12, 2035.

Under which plan were the Clene options granted?

They were granted under the Clene Inc. Amended 2020 Stock Plan.

How many derivative securities are beneficially owned after the transaction?

The filing shows 2,887 derivative securities beneficially owned.

What is the ownership form for the reported options?

The ownership is reported as Direct (D).

What is the reported price of the derivative security?

The price of the derivative security is listed as $0.