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ZyVersa Therapeutics, Inc. - ZVSA STOCK NEWS

Welcome to our dedicated page for ZyVersa Therapeutics news (Ticker: ZVSA), a resource for investors and traders seeking the latest updates and insights on ZyVersa Therapeutics stock.

ZyVersa Therapeutics, Inc. (Nasdaq: ZVSA) is a clinical-stage specialty biopharmaceutical company committed to developing first-in-class drugs for patients with renal and inflammatory diseases who have significant unmet medical needs. Leveraging advanced proprietary technologies, ZyVersa is focused on creating therapeutic solutions that address these critical health challenges.

ZyVersa's impressive pipeline features two main drug development platforms. The Cholesterol Efflux Mediator™ VAR 200 (2-hydroxypropyl-beta-cyclodextrin) is an injectable drug in clinical development for treating kidney diseases caused by lipid accumulation. Clinical trials for VAR 200 have shown promising results in animal models of diabetic kidney disease, focal segmental glomerulosclerosis (FSGS), and Alport syndrome (AS). The Phase 2a clinical trial protocol for diabetic kidney disease has recently received IRB approval, marking a significant milestone in the drug's development.

The second platform is the Inflammasome ASC Inhibitor IC 100, a novel humanized IgG4 monoclonal antibody. IC 100 inhibits the inflammasome adaptor protein ASC, which plays a crucial role in the body's inflammatory response. The drug is in preclinical development for treating various inflammatory conditions, including neurological diseases like Alzheimer's, multiple sclerosis, and traumatic brain injury. Recent research has highlighted IC 100's potential in addressing obesity-related inflammation and metabolic complications, further expanding its therapeutic scope.

Under the leadership of an experienced team with over 15 years of success in the biopharmaceutical industry, ZyVersa continues to advance its drug candidates towards clinical trials. The company's strategic partnerships and collaborations with notable research institutions like the University of Miami Miller School of Medicine further bolster its research and development efforts.

Financially, ZyVersa is navigating the challenges of a clinical-stage biopharmaceutical company. While the company reported a net loss of $98.3 million for the year ending December 31, 2023, it continues to secure funding through public and private equity, grants, and collaborations. Recent financial updates indicate a net loss improvement for Q1 2024, with operating expenses managed efficiently to support ongoing and future clinical trials.

For more detailed information, visit the ZyVersa Therapeutics website and stay updated with their latest news and developments.

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ZyVersa Therapeutics, Inc. (ZVSA) announced the development of Inflammasome ASC Inhibitor IC 100 to target damaging inflammation associated with obesity and other conditions. The company raised $2.7 Million from existing investors' exercise of warrants, influenced by positive news in the inflammasome inhibitor sector.
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ZyVersa Therapeutics, Inc. highlights data published in Nature reinforcing the rationale for their Inflammasome ASC Inhibitor IC 100 to combat damaging inflammation associated with obesity and its complications. The drug aims to inhibit inflammasomes and ASC specks to attenuate systemic release of inflammatory cytokines and cell death, potentially offering a therapeutic option for metabolic disorders and cancers linked to obesity.
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ZyVersa Therapeutics, Inc. announces availability of a new white paper titled 'Inflammasome ASC Inhibitor IC 100, Promising Therapeutic Potential For Neurological Diseases'. The white paper highlights preclinical research showing strong proof-of-concept for the drug in various neurological conditions.
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ZyVersa Therapeutics, Inc. highlights data from a review article showing the role of inflammasomes in neurological diseases. Their drug IC 100 targets ASC specks to block damaging inflammation, with promising potential for conditions like Alzheimer's and multiple sclerosis.
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ZyVersa Therapeutics, Inc. is a clinical stage specialty biopharmaceutical company developing first-in-class drugs for the treatment of renal and inflammatory diseases with high unmet medical needs. The company is advancing a pipeline of drug candidates with multiple programs built around two proprietary technologies – Cholesterol Efflux Mediator™ VAR 200 for treatment of kidney diseases, and Inflammasome ASC Inhibitor IC 100 for treatment of multiple CNS and peripheral inflammatory diseases. The CEO, Stephen C. Glover, will provide a corporate update at the BIO CEO & Investor Conference, discussing upcoming development milestones for the Phase 2a clinical trial in patients with diabetic kidney disease and the completion of the preclinical program for Inflammasome ASC Inhibitor IC 100.
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ZyVersa Therapeutics highlights a study linking NLRP3 inflammasome activation to insulin resistance and metabolic complications in obese children. The company is developing Inflammasome ASC Inhibitor IC 100 to address this issue.
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ZyVersa Therapeutics, Inc. announces the publication of a scientific paper in Alzheimer's & Dementia: Translational Research & Clinical Interventions, demonstrating the role of the inflammasome/ASC speck pathway in synaptic degeneration in Alzheimer’s Disease. The paper highlights the potential of ZyVersa’s Inflammasome ASC Inhibitor IC 100 in targeting ASC specks to block damaging inflammation in the central nervous system and peripheral tissues.
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ZyVersa Therapeutics, Inc. announces publication of an article in the peer-reviewed journal, Acta Neuropathologica Communications, demonstrating that inflammasome activation enhances cancer metastasis to the brain in women with TNBC. The company is developing Inflammasome ASC Inhibitor IC 100, which can inhibit up to 12 different inflammasomes and their associated ASC specks which perpetuate damaging inflammation.
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ZyVersa Therapeutics, Inc. (Nasdaq: ZVSA) announces 2024 outlook and development plans for first-in-class drugs targeting renal and inflammatory diseases. Co-Founder and CEO, Stephen C. Glover, discusses the potential of Cholesterol Efflux Mediator VAR 200 to improve kidney function and reduce kidney disease progression, as well as plans for Phase 2a trial with VAR 200 and completion of GLP toxicology studies with Inflammasome ASC Inhibitor IC 100.
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ZyVersa Therapeutics, Inc. (ZVSA) is developing two proprietary product platforms targeting renal and inflammatory diseases. The Cholesterol Efflux MediatorTM VAR 200 is designed to ameliorate renal lipid accumulation that damages the kidneys’ filtration system, leading to chronic kidney disease and its progression. The Inflammasome ASC Inhibitor IC 100 is designed to inhibit multiple inflammasome pathways to attenuate initiation and perpetuation of damaging inflammation pathogenic in numerous inflammatory diseases. ZyVersa has announced that Noble Capital Markets has initiated company-sponsored equity research coverage.
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FAQ

What is the current stock price of ZyVersa Therapeutics (ZVSA)?

The current stock price of ZyVersa Therapeutics (ZVSA) is $1.14 as of December 20, 2024.

What is the market cap of ZyVersa Therapeutics (ZVSA)?

The market cap of ZyVersa Therapeutics (ZVSA) is approximately 3.0M.

What is ZyVersa Therapeutics, Inc.?

ZyVersa Therapeutics, Inc. (Nasdaq: ZVSA) is a clinical-stage biopharmaceutical company developing first-in-class drugs for renal and inflammatory diseases.

What are ZyVersa's main drug platforms?

ZyVersa's main drug platforms are Cholesterol Efflux Mediator™ VAR 200 for kidney diseases and Inflammasome ASC Inhibitor IC 100 for inflammatory conditions.

What is the status of the VAR 200 clinical trials?

VAR 200 is in Phase 2a clinical trials for diabetic kidney disease, with IRB approval recently granted and trials set to begin in the first half of 2024.

What conditions does IC 100 target?

IC 100 targets various inflammatory conditions, including neurological diseases like Alzheimer's, multiple sclerosis, and traumatic brain injury, as well as obesity-related inflammation.

Who are ZyVersa's research partners?

ZyVersa collaborates with institutions like the University of Miami Miller School of Medicine to advance its research and development efforts.

What recent financial updates has ZyVersa reported?

For Q1 2024, ZyVersa reported a net loss improvement and efficient management of operating expenses to support ongoing and future clinical trials.

What technologies does ZyVersa utilize in its drug development?

ZyVersa leverages advanced proprietary technologies, including Cholesterol Efflux Mediator™ and Inflammasome ASC Inhibitor platforms, to develop its drugs.

How does IC 100 function?

IC 100 is a monoclonal antibody that inhibits the inflammasome adaptor protein ASC, attenuating inflammatory responses by blocking activation of IL-1β.

What is the significance of the recent IRB approval for VAR 200?

IRB approval for the Phase 2a clinical trial of VAR 200 in diabetic kidney disease is a key milestone, indicating readiness to begin human trials.

Where can I find more information about ZyVersa?

For more information, visit ZyVersa's official website at www.zyversa.com.

ZyVersa Therapeutics, Inc.

Nasdaq:ZVSA

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2.98M
2.50M
0.61%
4.47%
4.23%
Biotechnology
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