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Zentalis Pharmaceuticals, Inc. - ZNTL STOCK NEWS

Welcome to our dedicated page for Zentalis Pharmaceuticals news (Ticker: ZNTL), a resource for investors and traders seeking the latest updates and insights on Zentalis Pharmaceuticals stock.

Zentalis Pharmaceuticals, Inc. (NASDAQ: ZNTL) is a clinical-stage biopharmaceutical company dedicated to discovering and developing innovative small molecule therapeutics that target fundamental biological pathways in cancer. Utilizing its proprietary Integrated Discovery Engine, Zentalis aims to identify unique targets and develop novel, potentially best-in-class new chemical entities (NCEs) with differentiated product profiles.

The company's robust pipeline is highlighted by two lead product candidates: ZN-c5 and ZN-c3. ZN-c5 is being developed for the treatment of advanced estrogen receptor-positive, human epidermal growth factor receptor 2-negative (ER+/HER2-) breast cancer, while ZN-c3 targets advanced solid tumors and ovarian cancer. Zentalis is also developing azenosertib (ZN-c3), a WEE1 inhibitor, as a monotherapy and in combination with other agents to address multiple tumor types.

Recently, Zentalis announced plans to use the net proceeds from its latest offering to fund ongoing and planned clinical trials, as well as for working capital and other general corporate purposes. The company’s financial strategy is designed to support its operational expenses and capital expenditure requirements through 2026.

The company’s latest financial disclosures highlighted strong clinical data for azenosertib, showing an objective response rate of 36.8% in ovarian cancer and uterine serous carcinoma patients. Azenosertib, currently in multiple clinical trials, demonstrated encouraging efficacy both as a monotherapy and in combination with chemotherapy.

Headquartered in New York and San Diego, Zentalis is collaborating with top financial institutions like Morgan Stanley, Jefferies, and Guggenheim Securities to drive its growth. The company's strong cash position is bolstered by its recent offerings and ongoing support from financial advisors.

Continuing to advance its clinical strategies, Zentalis is focused on its fast-to-market approach for azenosertib, aiming to submit its first NDA in gynecologic malignancies by 2026. Furthermore, Zentalis is leveraging its expertise in cancer biology and medicinal chemistry to explore the potential of protein degraders and other innovative treatment modalities.

Stay updated on Zentalis Pharmaceuticals’ latest developments by visiting their official website or following them on social media platforms such as Twitter and LinkedIn.

Rhea-AI Summary
Zentalis Pharmaceuticals, Inc. announced updated data from a study of azenosertib monotherapy, showing an objective response rate (ORR) of 37% and a median progression-free survival (mPFS) of 6.5 months in ovarian and uterine serous carcinoma patients. The company plans to submit the first New Drug Application (NDA) for azenosertib in a gynecologic malignancy in 2026. They also highlighted their cash balance of $517 million as of September 30, 2023, and the appointment of Mark Lackner, Ph.D., as the new Chief Scientific Officer.
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Zentalis Pharmaceuticals has granted non-qualified stock options to five newly hired employees. The options allow the purchase of 271,000 shares of the company's common stock. The options have an exercise price of $16.35 per share and a 10-year term. They will vest over four years, with 25% vesting on the first anniversary and the remaining 75% vesting in equal monthly installments over the next three years.
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Zentalis Pharmaceuticals grants stock options to new employees
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Zentalis Pharmaceuticals CEO to participate in fireside chat at Morgan Stanley Healthcare Conference
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Zentalis Pharmaceuticals grants stock options to new employees
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Zentalis Pharmaceuticals, Inc. (Nasdaq: ZNTL) announced positive Phase 1b data for azenosertib monotherapy and azenosertib + chemotherapy combinations in ovarian cancer patients. The company raised $250.0 million from a recent offering, extending cash runway into 2026. The program highlights the identified monotherapy recommended Phase 2 dose, positive safety and efficacy data, and biomarker enrichment strategies. Corporate highlights include new appointments and a public offering.
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Zentalis Pharmaceuticals, Inc. (ZNTL) announced the granting of 275,000 non-qualified stock options to a newly hired employee under the 2022 Inducement Plan. The options have an exercise price of $26.25 per share, a 10-year term, and will vest over four years, subject to the employee's continued service to the company.
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Zentalis Pharmaceuticals, Inc. (Nasdaq: ZNTL) appoints Kimberly Freeman as Chief Strategy Officer, leveraging her 25 years of clinical development and strategic leadership experience, particularly in gynecologic malignancies and the DNA damage response pathway. She will support Zentalis' long-term portfolio strategy, focusing on advancing azenosertib to patients with ovarian and uterine cancers, and other Cyclin E1 positive tumor types where patients typically face poor prognosis.
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FAQ

What is the current stock price of Zentalis Pharmaceuticals (ZNTL)?

The current stock price of Zentalis Pharmaceuticals (ZNTL) is $3.18 as of December 23, 2024.

What is the market cap of Zentalis Pharmaceuticals (ZNTL)?

The market cap of Zentalis Pharmaceuticals (ZNTL) is approximately 213.8M.

What products is Zentalis Pharmaceuticals currently developing?

Zentalis is developing ZN-c5 for advanced ER+/HER2- breast cancer and ZN-c3 (azenosertib) for advanced solid tumors including ovarian cancer.

What is the purpose of Zentalis Pharmaceuticals' recent financial offering?

The company plans to use the proceeds to fund clinical trials, working capital, and general corporate purposes, ensuring operational stability through 2026.

What is azenosertib and why is it significant?

Azenosertib (ZN-c3) is a WEE1 inhibitor showing promising clinical data for treating ovarian cancer and uterine serous carcinoma as both a monotherapy and in combination with chemotherapy.

Where are Zentalis Pharmaceuticals' main operations located?

Zentalis Pharmaceuticals operates primarily out of New York and San Diego.

Who are Zentalis Pharmaceuticals' financial collaborators?

Morgan Stanley, Jefferies, SVB Securities, and Guggenheim Securities are among the financial institutions collaborating with Zentalis.

What is Zentalis’ Integrated Discovery Engine?

Zentalis' Integrated Discovery Engine is a proprietary drug discovery platform used to identify unique targets and develop novel small molecule therapeutics for cancer.

When does Zentalis plan to submit its first NDA for azenosertib?

Zentalis aims to submit its first NDA for azenosertib in gynecologic malignancies by 2026.

What are the recent clinical achievements of Zentalis Pharmaceuticals?

Zentalis has shown significant clinical data for azenosertib, particularly its effectiveness in treating ovarian cancer and uterine serous carcinoma.

How does Zentalis plan to use its expertise in cancer biology?

Zentalis leverages its expertise to advance research on protein degraders and explore innovative treatment modalities for cancer.

Where can one access more information about Zentalis Pharmaceuticals?

For more information, visit the Zentalis official website or follow them on social media platforms like Twitter and LinkedIn.

Zentalis Pharmaceuticals, Inc.

Nasdaq:ZNTL

ZNTL Rankings

ZNTL Stock Data

213.80M
64.53M
3.83%
98.06%
6.97%
Biotechnology
Pharmaceutical Preparations
Link
United States of America
SAN DIEGO