STOCK TITAN

Zentalis Pharmaceuticals, Inc. - ZNTL STOCK NEWS

Welcome to our dedicated page for Zentalis Pharmaceuticals news (Ticker: ZNTL), a resource for investors and traders seeking the latest updates and insights on Zentalis Pharmaceuticals stock.

Zentalis Pharmaceuticals, Inc. (NASDAQ: ZNTL) is a clinical-stage biopharmaceutical company dedicated to discovering and developing innovative small molecule therapeutics that target fundamental biological pathways in cancer. Utilizing its proprietary Integrated Discovery Engine, Zentalis aims to identify unique targets and develop novel, potentially best-in-class new chemical entities (NCEs) with differentiated product profiles.

The company's robust pipeline is highlighted by two lead product candidates: ZN-c5 and ZN-c3. ZN-c5 is being developed for the treatment of advanced estrogen receptor-positive, human epidermal growth factor receptor 2-negative (ER+/HER2-) breast cancer, while ZN-c3 targets advanced solid tumors and ovarian cancer. Zentalis is also developing azenosertib (ZN-c3), a WEE1 inhibitor, as a monotherapy and in combination with other agents to address multiple tumor types.

Recently, Zentalis announced plans to use the net proceeds from its latest offering to fund ongoing and planned clinical trials, as well as for working capital and other general corporate purposes. The company’s financial strategy is designed to support its operational expenses and capital expenditure requirements through 2026.

The company’s latest financial disclosures highlighted strong clinical data for azenosertib, showing an objective response rate of 36.8% in ovarian cancer and uterine serous carcinoma patients. Azenosertib, currently in multiple clinical trials, demonstrated encouraging efficacy both as a monotherapy and in combination with chemotherapy.

Headquartered in New York and San Diego, Zentalis is collaborating with top financial institutions like Morgan Stanley, Jefferies, and Guggenheim Securities to drive its growth. The company's strong cash position is bolstered by its recent offerings and ongoing support from financial advisors.

Continuing to advance its clinical strategies, Zentalis is focused on its fast-to-market approach for azenosertib, aiming to submit its first NDA in gynecologic malignancies by 2026. Furthermore, Zentalis is leveraging its expertise in cancer biology and medicinal chemistry to explore the potential of protein degraders and other innovative treatment modalities.

Stay updated on Zentalis Pharmaceuticals’ latest developments by visiting their official website or following them on social media platforms such as Twitter and LinkedIn.

Rhea-AI Summary
Zentalis Pharmaceuticals, Inc. announces robust azenosertib clinical development plan with multiple clinical catalysts expected in 2024. The company's cash balance stood at $483 million as of December 31, 2023, providing funding into 2026. Key highlights include promising clinical data for azenosertib in ovarian cancer and uterine serous carcinoma, progress in ongoing Phase 1 trials, and strategic leadership team additions.
Rhea-AI Impact
Rhea-AI Sentiment
End-of-Day
4.47%
Tags
-
Rhea-AI Summary
Zentalis Pharmaceuticals, Inc. announced that Kimberly Blackwell, M.D., CEO, will participate in a webcast fireside chat at the Oppenheimer Healthcare Life Sciences Conference. The event is scheduled for February 14, 2024, at 12:40 p.m. ET. The webcast will be available on the company's website for live viewing and as an archived recording.
Rhea-AI Impact
Rhea-AI Sentiment
End-of-Day
-5.83%
Tags
conferences
-
Rhea-AI Summary
Zentalis Pharmaceuticals, Inc. announced the granting of non-qualified stock options and restricted stock units to six newly hired employees. The options have an exercise price of $11.69 per share and a 10-year term, vesting over four years. The restricted stock units will also vest over four years. The grants were made under the 2022 Inducement Plan as an inducement for entering into employment with Zentalis.
Rhea-AI Impact
Rhea-AI Sentiment
End-of-Day
-0.86%
Tags
none
Rhea-AI Summary
Zentalis Pharmaceuticals, Inc. appoints Diana Hausman, M.D. as Chief Medical Officer and Kyle Rasbach, Ph.D., Pharm.D. as Chief Business Officer. Dr. Hausman brings extensive oncology development experience, having served as Chief Medical Officer in several biotech companies. Dr. Rasbach, with a background in healthcare equity research, joins from Eventide Asset Management. The company expresses gratitude to Dr. Carrie Brownstein, who is stepping down, for her contributions to advancing azenosertib in the clinic.
Rhea-AI Impact
Rhea-AI Sentiment
End-of-Day
-0.68%
Tags
none
-
Rhea-AI Summary
Immunome, Inc. (IMNM) and Zentalis Pharmaceuticals, Inc. (ZNTL) have entered into an exclusive, worldwide license agreement for preclinical ROR1 ADC, with ZPC-21 on track for IND submission in 1Q 2025. Immunome will pay $35 million in cash and common stock to Zentalis, with potential milestone payments of up to $275 million and mid-to-high single-digit royalties.
Rhea-AI Impact
Rhea-AI Sentiment
End-of-Day
7.91%
Tags
none
-
Rhea-AI Summary
Zentalis Pharmaceuticals, Inc. (Nasdaq: ZNTL) granted non-qualified stock options to two newly hired employees under the 2022 Inducement Plan. The options have an exercise price of $15.99 per share, a 10-year term, and will vest over four years. Vesting is subject to the employee’s continued service to Zentalis on each vesting date.
Rhea-AI Impact
Rhea-AI Sentiment
End-of-Day
-2.44%
Tags
none
Rhea-AI Summary
Zentalis Pharmaceuticals, Inc. (Nasdaq: ZNTL) granted 42,000 stock options and 28,000 restricted stock units to a newly hired employee under the 2022 Inducement Plan. The options have an exercise price of $11.34 per share, a 10-year term, and will vest over four years, while the restricted stock units will also vest over four years. Vesting is subject to the employee's continued service to Zentalis on each vesting date.
Rhea-AI Impact
Rhea-AI Sentiment
End-of-Day
1.94%
Tags
none
-
Rhea-AI Summary
Zentalis Pharmaceuticals, Inc. (Nasdaq: ZNTL) to hold investor call and participate in fireside chat at Jefferies London Healthcare Conference. CEO and CFO to discuss azenosertib ovarian cancer clinical updates with key opinion leader on November 10th, 2023. Live webcasts and archived recordings available on company website.
Rhea-AI Impact
Rhea-AI Sentiment
End-of-Day
-0.3%
Tags
conferences
-
Rhea-AI Summary
Zentalis Pharmaceuticals, Inc. announced updated data from a study of azenosertib monotherapy, showing an objective response rate (ORR) of 37% and a median progression-free survival (mPFS) of 6.5 months in ovarian and uterine serous carcinoma patients. The company plans to submit the first New Drug Application (NDA) for azenosertib in a gynecologic malignancy in 2026. They also highlighted their cash balance of $517 million as of September 30, 2023, and the appointment of Mark Lackner, Ph.D., as the new Chief Scientific Officer.
Rhea-AI Impact
Rhea-AI Sentiment
End-of-Day
-30.2%
Tags
Rhea-AI Summary
Zentalis Pharmaceuticals has granted non-qualified stock options to five newly hired employees. The options allow the purchase of 271,000 shares of the company's common stock. The options have an exercise price of $16.35 per share and a 10-year term. They will vest over four years, with 25% vesting on the first anniversary and the remaining 75% vesting in equal monthly installments over the next three years.
Rhea-AI Impact
Rhea-AI Sentiment
End-of-Day
1.53%
Tags
none

FAQ

What is the current stock price of Zentalis Pharmaceuticals (ZNTL)?

The current stock price of Zentalis Pharmaceuticals (ZNTL) is $3.23 as of November 22, 2024.

What is the market cap of Zentalis Pharmaceuticals (ZNTL)?

The market cap of Zentalis Pharmaceuticals (ZNTL) is approximately 238.4M.

What products is Zentalis Pharmaceuticals currently developing?

Zentalis is developing ZN-c5 for advanced ER+/HER2- breast cancer and ZN-c3 (azenosertib) for advanced solid tumors including ovarian cancer.

What is the purpose of Zentalis Pharmaceuticals' recent financial offering?

The company plans to use the proceeds to fund clinical trials, working capital, and general corporate purposes, ensuring operational stability through 2026.

What is azenosertib and why is it significant?

Azenosertib (ZN-c3) is a WEE1 inhibitor showing promising clinical data for treating ovarian cancer and uterine serous carcinoma as both a monotherapy and in combination with chemotherapy.

Where are Zentalis Pharmaceuticals' main operations located?

Zentalis Pharmaceuticals operates primarily out of New York and San Diego.

Who are Zentalis Pharmaceuticals' financial collaborators?

Morgan Stanley, Jefferies, SVB Securities, and Guggenheim Securities are among the financial institutions collaborating with Zentalis.

What is Zentalis’ Integrated Discovery Engine?

Zentalis' Integrated Discovery Engine is a proprietary drug discovery platform used to identify unique targets and develop novel small molecule therapeutics for cancer.

When does Zentalis plan to submit its first NDA for azenosertib?

Zentalis aims to submit its first NDA for azenosertib in gynecologic malignancies by 2026.

What are the recent clinical achievements of Zentalis Pharmaceuticals?

Zentalis has shown significant clinical data for azenosertib, particularly its effectiveness in treating ovarian cancer and uterine serous carcinoma.

How does Zentalis plan to use its expertise in cancer biology?

Zentalis leverages its expertise to advance research on protein degraders and explore innovative treatment modalities for cancer.

Where can one access more information about Zentalis Pharmaceuticals?

For more information, visit the Zentalis official website or follow them on social media platforms like Twitter and LinkedIn.

Zentalis Pharmaceuticals, Inc.

Nasdaq:ZNTL

ZNTL Rankings

ZNTL Stock Data

238.38M
68.53M
3.47%
98.18%
9.92%
Biotechnology
Pharmaceutical Preparations
Link
United States of America
SAN DIEGO