WUXI BIOLOGICS UNSP/ADR - WXXWY STOCK NEWS

WuXi Biologics released its 2023 ESG Report, showcasing significant progress in sustainability initiatives. The company achieved reductions in greenhouse gas emissions and water consumption intensity, recognized by major ESG rating agencies. WuXi Biologics demonstrated commitment to ESG goals, governance, climate change action, value chain sustainability, diversity, and corporate social responsibility.

WuXi Biologics (2269.HK) has been recognized for its leadership in corporate transparency and performance on water security by CDP, securing a spot on its annual 'A List'. The company achieved an 'A' score in the Water Security category, placing it in the top 2% of over 23,000 evaluated companies. CEO Dr. Chris Chen highlighted sustainability as a key focus for the company's development.

WuXi Biologics achieves Leadership level recognition in 2023 Climate Change Assessment by CDP with an 'A-' score, surpassing sector and regional averages. The company's proactive efforts in environmental management and transparency are highlighted, with a commitment to science-based carbon targets and emission-reduction roadmaps.

WuXi Biologics (2269.HK) has been named a 2024 Industry Top-Rated and Regional Top-Rated Company by Morningstar Sustainalytics for the fourth consecutive year. The company ranks in the top 2% of nearly 1,000 companies in the pharmaceutical sector, showcasing strong ESG achievements.

WuXi Biologics successfully completes the first manufacturing run at its drug substance facility MFG7 in Ireland, achieving the largest manufacturing scale to date by combining four 4,000-liter single-use bioreactors. The Cost of Goods (COGS) from this run is comparable to that of a 16,000-liter traditional stainless-steel bioreactor, reinforcing the comparable cost seen in over 100 runs at 12,000-liter scale single-use bioreactors. The Ireland site also received the Facility of the Year Award (FOYA) in the Operations category from ISPE in 2023 and attained ISO certifications for energy management, environmental management, and occupational health and safety management.

WuXi Biologics launches WuXiaADCC PLUSTM, a high-yielding mammalian cell line platform for the development and manufacturing of afucosylated antibodies to enhance antibody-dependent cell-mediated cytotoxicity (ADCC) response, crucial for targeted antibody-based immunotherapy approaches.

WuXi Biologics announced the granting of a patent for their WuXiBodyTM platform, a highly flexible engineering platform that enhances the characteristics of bispecifics. The platform has been granted patents in the U.S., Japan, and China and has been widely adopted globally since its launch in 2018. WuXiBodyTM can effectively break through the CMC barriers for the development of bispecific antibodies, shorten the process by 6-18 months, and significantly reduce manufacturing costs compared to other platforms. The platform enables almost any mAb sequence pairs to be assembled into bispecific constructs with low immunogenicity risk and a long in vivo half-life. As of December 31, 2023, there are 45 out-licensed WuXiBodyTM projects in various stages, with four in Phase Ⅰ clinical development. Two WuXiBodyTM projects are expected to have IND applications approved in 2024.

WuXi Biologics (2269. HK) signs research service agreement with BioNTech SE (Nasdaq: BNTX) to discover two undisclosed targets of preclinical investigational monoclonal antibodies. WuXi Biologics to receive $20 million upfront payment and additional payments for research, development, regulatory, and commercial milestones, as well as tiered royalties.

WuXi Biologics (2269.HK) to expand commercial manufacturing capacity in the U.S., increasing total manufacturing capacity to 36,000 liters, creating 200 new jobs, and aiming for GMP release in 2026.