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Healthy Longevity is One of Key Development Goals of ANEW’s Novel Gene Therapy

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ANEW MEDICAL, INC. (NASDAQ: WENA) has announced two key goals for its cell and gene therapy development: enhancing healthy longevity potential and developing treatments for age-related and neurodegenerative diseases. The company has secured exclusive worldwide rights and patents for the secreted form of Klotho (s-KL), often called 'the anti-aging gene'. ANEW's hypothesis suggests that maintaining high Klotho levels leads to a long, healthy life, while depleted levels may cause neurodegenerative diseases.

ANEW plans to study blood samples from Okinawa centenarians, comparing them to a cohort with age-related disorders. The company has partnered with the Okinawa Centenarian Research Center for Longevity, including renowned scientists as advisors. ANEW aims to enter clinical trials soon and leverage its recent Nasdaq listing to expedite development of Klotho-based therapies.

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Positive

  • Secured exclusive worldwide rights and patents for Klotho gene (s-KL) in major markets
  • Partnership with Okinawa Centenarian Research Center for Longevity and renowned scientists as advisors
  • Recent Nasdaq listing to expedite development programs
  • Potential to enter clinical trials in the near future

Negative

  • No current FDA approval for clinical trials
  • Hypothesis on Klotho's role in longevity and disease prevention still needs further validation

News Market Reaction 1 Alert

-8.39% News Effect

On the day this news was published, WENA declined 8.39%, reflecting a notable negative market reaction.

Data tracked by StockTitan Argus on the day of publication.

Company will use novel, patented Klotho Gene (s-KL) in studies

NEW YORK, Sept. 04, 2024 (GLOBE NEWSWIRE) -- ANEW MEDICAL, INC. (NASDAQ: WENA), a U.S. biotechnology company, announced that it has two distinct goals for its pioneering cell and gene therapy development. One is to enhance the potential of people achieving a healthy long life, and the other is the development of effective treatments for age-related disorders and neurodegenerative diseases such as ALS, Alzheimer’s and Parkinson’s disease.

ANEW has secured exclusive worldwide rights and issued patents in the USA, Canada, Europe, Hong Kong and China, covering the secreted form of Klotho, known scientifically as s-KL. Klotho is often referred to as “the anti-aging gene.” It is named after the Greek goddess who is said to spin the thread of life.

Existing data supports ANEW’s scientific hypothesis that maintaining high levels of Klotho as we age leads to a long and healthy life (often into the 100s) whereas depleted levels of Klotho may lead to neurodegenerative diseases such as ALS, Alzheimer’s and Parkinson’s Diseases as well as other age-related disorders including cardiovascular conditions, osteoporosis, and the muscle-wasting disorder, sarcopenia. ANEW hopes to further demonstrate the validity of its hypothesis by examining the stored blood samples of a cohort of people who stayed healthy and reached very old age, many in excess of 100 years, in Okinawa, Japan. Okinawa is one of the famous “Blue Zones” of the world (see the Netflix documentary series “Living to 100”). The results of this study will be compared to a matching cohort of an aging population who have experienced neurodegenerative diseases such as ALS, Alzheimer’s, Parkinson’s and other age-related disorders.

ANEW is focused on both enhancing the potential for people to experience healthy longevity as well as on the development of cell and gene-based therapies to treat neurodegenerative and age-related disorders based on its patented Klotho technology. The company hopes to obtain FDA agreement in the near future to enter the clinic in at least one indication area. It has also recently announced a partnership with the key scientists involved in the Okinawa Centenarian Research Center for Longevity who are retained as Advisor on longevity and the development of new pharmaceutical treatments. This includes Drs. Craig and Bradley Willcox, authors of the best-selling, Oprah Winfrey recommended, book, “The Okinawa Program: How the World’s Longest-Lived People Achieve Everlasting Health-And How You Can Too.”

Commenting on this development, Dr. Joseph Sinkule, the Founder, Chairman and CEO of ANEW, stated: “Our recent Nasdaq listing will provide us with the opportunity to more expeditiously pursue our development programs to produce cell and gene therapies based on our proprietary Klotho technology. Also, having Drs. Michio Shimabukuro, Richard Allsopp, and Craig and Bradley Willcox of the Okinawa Centenarian Research Center for Longevity Sciences as retained Advisors to our company will be highly important in guiding our development based on their scientific insights in the field of longevity and the data contained in the stored blood samples of Okinawa centenarians.”

About ANEW MEDICAL, INC.
ANEW MEDICAL, INC. (NASDAQ: WENA) is a biopharmaceutical company specializing in the development of patented, novel disease-modifying technologies targeting the brain and central nervous system (CNS) that are seen as key developments in treating neurodegenerative and age-related disorders. The Company obtained exclusive worldwide rights to platform technologies and knowhow to develop cutting edge protein, gene and cell therapies to treat age-related pathologies such as ALS, Alzheimer’s and Parkinson’s disease, multiple sclerosis and rare neurodegenerative disorders. The company is managed by a team of individuals and advisors who are highly experienced in biopharmaceutical product development and commercialization.

For more information, contact:
Eric Boyd
Investor Relations
Email: IR@anewmeds.com

Forward-Looking Statements:
This press release contains forward-looking statements. These statements are made under the “safe harbor” provisions of the U.S. Private Securities Litigation Reform Act of 1995. These forward-looking statements generally are identified by the words “believe,” “project,” “expect,” “anticipate,” “estimate,” “intend,” “strategy,” “future,” “opportunity,” “plan,” “may,” “should,” “will,” “would,” “will be,” “will continue,” “will likely result,” and similar expressions. Without limiting the generality of the foregoing, the forward-looking statements in this press release include descriptions of the Company’s future commercial operations. Forward-looking statements are predictions, projections and other statements about future events that are based on current expectations and assumptions and, as a result, are subject to risks and uncertainties. Many factors could cause actual future events to differ materially from the forward-looking statements in this press release, such as the Company’s inability to implement its business plans, identify and realize additional opportunities, or meet or exceed its financial projections and changes in the regulatory or competitive environment in which the Company operates. You should carefully consider the foregoing factors and the other risks and uncertainties described in the documents filed or to be filed by the Company with the U.S. Securities and Exchange Commission (the “SEC”) from time to time, which could cause actual events and results to differ materially from those contained in the forward-looking statements. Copies of these documents are available on the SEC’s website, www.sec.gov. All information provided herein is as of the date of this press release, and the Company undertakes no obligation to update any forward-looking statement, except as required under applicable law.


FAQ

What are ANEW MEDICAL's (WENA) main goals for its gene therapy development?

ANEW MEDICAL (WENA) has two main goals: 1) enhancing the potential for healthy longevity, and 2) developing treatments for age-related disorders and neurodegenerative diseases such as ALS, Alzheimer's, and Parkinson's disease.

What is the significance of the Klotho gene in ANEW MEDICAL's (WENA) research?

ANEW MEDICAL (WENA) has secured exclusive rights to the secreted form of Klotho (s-KL), often called 'the anti-aging gene'. Their hypothesis suggests that maintaining high Klotho levels leads to a long, healthy life, while depleted levels may cause neurodegenerative diseases.

How is ANEW MEDICAL (WENA) planning to validate its Klotho gene hypothesis?

ANEW MEDICAL (WENA) plans to study blood samples from Okinawa centenarians and compare them to a cohort with age-related disorders to validate their hypothesis on the role of Klotho in longevity and disease prevention.

Who are the key scientific advisors partnering with ANEW MEDICAL (WENA)?

ANEW MEDICAL (WENA) has partnered with scientists from the Okinawa Centenarian Research Center for Longevity, including Drs. Michio Shimabukuro, Richard Allsopp, and Craig and Bradley Willcox, authors of 'The Okinawa Program'.
ANEW MEDICAL, INC.

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Biological Products, (no Disgnostic Substances)
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