Voyager Therapeutics Inc Stock Price, News & Analysis

Voyager Therapeutics (VYGR) presents significant advancements at the ASGCT Annual Meeting, showcasing preclinical data on its novel TRACER™ AAV capsids, demonstrating enhanced CNS tropisms and cross-species translatability. Key highlights include a license agreement with Novartis, providing $54 million upfront for potential CNS applications. The company reported Q1 2022 revenues of $0.7 million, down from $6.5 million YoY, and a net loss of $21.3 million. Strong cash position of $166.8 million expected to fund operations into 2024.

Voyager Therapeutics (NASDAQ: VYGR) has announced nine presentations for the upcoming ASGCT 2022 meeting from May 16-19 in Washington, D.C. Highlights include new findings on TRACER™-generated AAV capsids, focusing on glial cell tropism, and a novel vectorized antibody approach targeting metastatic breast cancer. Notable presentations will cover improvements in CNS-targeted AAV vectors and gene therapies for ALS and other neurological diseases. CEO Al Sandrock emphasized the importance of these data in shaping Voyager's pipeline strategy.

Voyager Therapeutics announces the appointment of Dr. Alfred W. Sandrock, Jr. as CEO, succeeding Michael Higgins who served as interim CEO since June 2021. Dr. Sandrock, a prominent neuroscientist with a strong background in therapeutic development, aims to enhance Voyager's efforts in AAV gene therapy. His leadership is expected to drive advancements in Voyager's TRACER™ capsid discovery platform, potentially broadening applications for various diseases. The company is focused on achieving human proof of concept for its internal pipeline and has established licensing agreements with major pharmaceutical firms.

Voyager Therapeutics, Inc. (Nasdaq: VYGR) has announced a license option agreement with Novartis for access to its TRACER™ AAV capsids, targeting three CNS applications and options for two additional targets. This deal, alongside a previous Pfizer agreement, extends Voyager's cash runway into 2024 with total upfront payments of $84 million. The company reported a net income of $5.7 million for Q4 2021, improving from a loss in Q4 2020. However, the full year net loss was $71.2 million, primarily due to terminated collaborations. Leadership changes include the appointment of Al Sandrock, Jr. to the Board.

Voyager Therapeutics has entered a significant agreement with Novartis, receiving $54 million upfront and potential milestone payments up to $1.7 billion. The deal allows Novartis access to Voyager's TRACER AAV capsids for three central nervous system (CNS) targets, with options for two more. Voyager could also gain royalties from product sales. The TRACER platform is expected to enhance gene therapy delivery, reducing toxicity risks. This follows a previous collaboration with Pfizer, emphasizing Voyager’s growing capabilities in AAV gene therapy.

Voyager Therapeutics (Nasdaq: VYGR), a gene therapy innovator, has announced its participation in two upcoming virtual investor conferences. The company will present at the SVB Leerink 11th Annual Global Healthcare Conference on Feb. 18, 2022, at 9:20 a.m. ET, and participate in a corporate panel at the Cowen 42nd Annual Health Care Conference on Mar. 9, 2022, at 12:50 p.m. ET. Investors can access the sessions on Voyager's website and replays will be available for at least 30 days.

Voyager Therapeutics (Nasdaq: VYGR) announced the appointment of Alfred W. Sandrock, Jr. to its Board of Directors and the promotion of Robin Swartz to Chief Operating Officer, effective February 7, 2022. Dr. Sandrock, a seasoned drug developer with extensive experience at Biogen, will help steer Voyager's strategies for its TRACER™ AAV capsid screening platform and foster collaborations. Ms. Swartz will oversee several operational departments, marking a strategic leadership change aimed at enhancing the company's gene therapy initiatives.

Voyager Therapeutics (Nasdaq: VYGR) has presented preclinical data showing that its proprietary AAV vector, developed using TRACER™ technology, effectively targets HER2+ breast cancer brain metastases. The findings indicate that intravenous dosing of this vector leads to significant tumor reduction and improved survival rates in mouse models. The anti-HER2 antibody produced through this method achieves high concentrations in cerebrospinal fluid, suggesting potential for effective treatment against CNS tumors. Voyager plans to continue optimizing this innovative gene therapy approach.

Voyager Therapeutics (Nasdaq: VYGR) announced the presentation of preclinical data from its vectorized antibody program at the 26th Annual Society for Neuro-Oncology Meeting on Nov. 19, 2021. The presentation, titled AAV mediated brain delivery of an ADCC-enhanced antibody obviates xenograft growth in mouse models of HER2+ breast cancer brain metastasis, will be delivered by Dan R. Laks, Ph.D., at 4:15 p.m. ET. This represents a significant advancement in the development of AAV gene therapy technology, aiming to treat severe diseases through innovative approaches.