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vTv Therapeutics Inc. - VTVT STOCK NEWS

Welcome to our dedicated page for vTv Therapeutics news (Ticker: VTVT), a resource for investors and traders seeking the latest updates and insights on vTv Therapeutics stock.

vTv Therapeutics Inc. (Nasdaq: VTVT) is a clinical-stage biopharmaceutical company committed to discovering and developing orally administered treatments for metabolic and inflammatory diseases. The company aims to address unmet medical needs through its innovative technology that modulates human proteins into effective medicines. vTv Therapeutics' diverse pipeline includes small molecule clinical and pre-clinical drug candidates targeting a range of conditions such as central nervous system disorders, diabetes, metabolic disorders, inflammation, and cancer.

Leading vTv Therapeutics' pipeline is cadisegliatin (TTP399), an investigational liver-selective glucokinase activator being developed as an adjunctive therapy to insulin for type 1 diabetes (T1D). Cadisegliatin is currently in preparation for Phase 3 clinical trials, with the first study expected to commence in mid-2024. In addition, vTv is exploring further indications for cadisegliatin in type 2 diabetes and other chronic conditions in collaboration with G42 Healthcare Research Technology Projects LLC and IROS, a UAE-based health technology group.

The company has achieved several milestones, including a strategic partnership with Reneo Pharmaceuticals for its PPARδ agonist program. This collaboration includes the potential for significant milestone payments and commercial royalties contingent on the success of Reneo's lead program, mavodelpar.

Apart from its focus on diabetes, vTv Therapeutics is also advancing other promising candidates. These include:

  • TTP273: A treatment aimed at metabolic diseases.
  • HPP737 and HPP593: Targeting inflammatory disorders.
  • Azeliragon: Licensed to Cantex Pharmaceuticals for further development in treating glioblastoma and pancreatic cancer.

vTv Therapeutics continues to build strong financial support, backed by proceeds from strategic sales and investments. Recently, the company secured funds through a private investment in public equity (PIPE) deal to support the upcoming Phase 3 trial of cadisegliatin.

Overall, vTv Therapeutics Inc. is positioned at the forefront of innovative treatments, leveraging its small molecule drug candidates to potentially transform the management of chronic diseases and improve patient outcomes.

Rhea-AI Summary
vTv Therapeutics Inc. reported financial results for Q4 and full year 2023, with a cash position of $9.4 million as of December 31, 2023. The company completed a $51 million private placement for Phase 3 trial of cadisegliatin for type 1 diabetes. Recent milestones include the submission of the study protocol to the FDA and upcoming Phase 2 study in type 2 diabetes.
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vTv Therapeutics Inc. announces the submission of the study protocol to the FDA for its Phase 3 trial evaluating cadisegliatin as an adjunctive therapy to insulin for type 1 diabetes. The trial aims to enroll 150 patients across 20 sites in the US, with the primary endpoint being the comparison of hypoglycemic events between cadisegliatin-treated and placebo groups.
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vTv Therapeutics Inc. announces participation in TD Cowen 44th Annual Healthcare Conference to present on cadisegliatin as adjunctive therapy for type 1 diabetes. The presentation is scheduled for March 5, 2024, at 9:50 AM ET, with a live webcast available on the company's investor relations website.
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vTv Therapeutics Inc. announces closing of a private placement to fund the first Phase 3 study of cadisegliatin for the treatment of type 1 diabetes. The company raised $51 million through the private placement, reducing its Board of Directors and bringing in new high-quality investors.
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Cantex Pharmaceuticals, Inc. announced that CEO Stephen Marcus will participate in the BIO CEO & Investor Conference in New York City. The company is focused on developing therapies for cancer and other medical conditions. Cantex is developing azeliragon, an inhibitor of RAGE, with ongoing Phase 2 trials in various cancers and a Phase 3 trial in pneumonia patients.
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vTv Therapeutics Inc. (VTVT) reports Q3 2023 financial results and corporate developments, highlighting the appointment of Dr. Thomas Strack as Chief Medical Officer and a common stock repurchase agreement with Reneo Pharmaceuticals. With a cash position of $8.2 million, R&D expenses of $2.8 million, and a net loss of $6.7 million, the company anticipates 2024 to be transformational.
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vTv Therapeutics Inc. (Nasdaq: VTVT) announced that its CFO, CSO, and CMO will present at the Stifel 2023 Healthcare Conference on November 15, 2023, to discuss the development of cadisegliatin (TTP399) as an adjunctive therapy to insulin for the treatment of type 1 diabetes. A live webcast will be available for investors, and one-on-one meetings can be scheduled with vTv’s management.
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vTv Therapeutics Inc. has appointed Thomas Strack, M.D. as Chief Medical Officer. Dr. Strack brings extensive drug development and clinical expertise to the company, with over 30 years of experience in academic clinical medicine and pharmaceutical drug development. He will play a prominent role in the execution of the planned Phase 3 program for cadisegliatin as an adjunctive therapy to insulin for the treatment of type 1 diabetes.
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vTv Therapeutics Inc. has entered into a common stock repurchase agreement with Reneo Pharmaceuticals, Inc. Reneo has purchased all of its common stock granted to vTv under the Reneo License Agreement for approximately $4.4 million. The proceeds will provide financial support for vTv as they prepare for the launch of the cadisegliatin Phase 3 program in T1D.
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Cantex Pharmaceuticals and Michigan Medicine have initiated a Phase 3 clinical trial for azeliragon in COVID-19 patients to decrease complications. Azeliragon is an inhibitor of RAGE and blocks suPAR effects. The trial aims to evaluate safety and efficacy.
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FAQ

What is the current stock price of vTv Therapeutics (VTVT)?

The current stock price of vTv Therapeutics (VTVT) is $14.96 as of December 20, 2024.

What is the market cap of vTv Therapeutics (VTVT)?

The market cap of vTv Therapeutics (VTVT) is approximately 37.9M.

What is the main focus of vTv Therapeutics Inc.?

vTv Therapeutics Inc. is focused on developing orally administered treatments for metabolic and inflammatory diseases to address unmet medical needs.

What is cadisegliatin (TTP399)?

Cadisegliatin (TTP399) is an investigational liver-selective glucokinase activator being developed as an adjunctive therapy to insulin for type 1 diabetes (T1D).

What are some other drug candidates in vTv Therapeutics' pipeline?

Other candidates include TTP273, HPP737, HPP593, azeliragon, HPP971, HPP3033, and TTP-RA.

What is the partnership between vTv Therapeutics and Reneo Pharmaceuticals?

vTv granted Reneo an exclusive worldwide license for its PPARδ agonist program, including potential milestone payments and commercial royalties.

What recent financial moves has vTv Therapeutics made?

vTv raised funds through a private investment in public equity (PIPE) to support the Phase 3 study of cadisegliatin.

When is the Phase 3 trial for cadisegliatin expected to start?

The Phase 3 study for cadisegliatin is expected to initiate in mid-2024.

What other conditions are being targeted by vTv's development partners?

Additional indications include type 2 diabetes, chronic obstructive pulmonary disease, primary mitochondrial myopathy, and various cancers.

What are the potential benefits of the cadisegliatin therapy?

Cadisegliatin aims to reduce hypoglycemic episodes in type 1 diabetes patients, potentially improving glycemic control and quality of life.

What is azeliragon, and who is developing it?

Azeliragon is an orally administered capsule targeting glioblastoma and pancreatic cancer, developed by Cantex Pharmaceuticals under license from vTv.

How does vTv Therapeutics plan to use the proceeds from recent investments?

The proceeds will be used to fund the first Phase 3 study of cadisegliatin and support other research and development activities.

vTv Therapeutics Inc.

Nasdaq:VTVT

VTVT Rankings

VTVT Stock Data

37.93M
1.66M
38.82%
14.95%
1.19%
Biotechnology
Pharmaceutical Preparations
Link
United States of America
HIGH POINT