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vTv Therapeutics Inc. - VTVT STOCK NEWS

Welcome to our dedicated page for vTv Therapeutics news (Ticker: VTVT), a resource for investors and traders seeking the latest updates and insights on vTv Therapeutics stock.

vTv Therapeutics Inc. (Nasdaq: VTVT) is a clinical-stage biopharmaceutical company committed to discovering and developing orally administered treatments for metabolic and inflammatory diseases. The company aims to address unmet medical needs through its innovative technology that modulates human proteins into effective medicines. vTv Therapeutics' diverse pipeline includes small molecule clinical and pre-clinical drug candidates targeting a range of conditions such as central nervous system disorders, diabetes, metabolic disorders, inflammation, and cancer.

Leading vTv Therapeutics' pipeline is cadisegliatin (TTP399), an investigational liver-selective glucokinase activator being developed as an adjunctive therapy to insulin for type 1 diabetes (T1D). Cadisegliatin is currently in preparation for Phase 3 clinical trials, with the first study expected to commence in mid-2024. In addition, vTv is exploring further indications for cadisegliatin in type 2 diabetes and other chronic conditions in collaboration with G42 Healthcare Research Technology Projects LLC and IROS, a UAE-based health technology group.

The company has achieved several milestones, including a strategic partnership with Reneo Pharmaceuticals for its PPARδ agonist program. This collaboration includes the potential for significant milestone payments and commercial royalties contingent on the success of Reneo's lead program, mavodelpar.

Apart from its focus on diabetes, vTv Therapeutics is also advancing other promising candidates. These include:

  • TTP273: A treatment aimed at metabolic diseases.
  • HPP737 and HPP593: Targeting inflammatory disorders.
  • Azeliragon: Licensed to Cantex Pharmaceuticals for further development in treating glioblastoma and pancreatic cancer.

vTv Therapeutics continues to build strong financial support, backed by proceeds from strategic sales and investments. Recently, the company secured funds through a private investment in public equity (PIPE) deal to support the upcoming Phase 3 trial of cadisegliatin.

Overall, vTv Therapeutics Inc. is positioned at the forefront of innovative treatments, leveraging its small molecule drug candidates to potentially transform the management of chronic diseases and improve patient outcomes.

Rhea-AI Summary
Cantex Pharmaceuticals and Allegheny Health Network initiate a Phase 1/2 study on azeliragon for pancreatic cancer patients refractory to first-line treatment. The study aims to assess safety and efficacy of the drug, which inhibits the RAGE receptor implicated in cancer growth and spread. The drug has shown good tolerance in previous trials. Cantex also has ongoing Phase 2 trials in other cancer indications and COVID-19 patients. The initiation of the study is a positive development for Cantex Pharmaceuticals.
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Cantex Pharmaceuticals initiates Phase 2 study with Lenox Hill Hospital to assess azeliragon's effectiveness in treating unmethylated glioblastoma.
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Cantex Pharmaceuticals initiates Phase 2 trial for azeliragon in brain metastases treatment, expanding indications for the drug.
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Cantex Pharmaceuticals announces publication showing suppression of metastasis and tumor progression in triple-negative breast cancer by RAGE inhibition with azeliragon
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FAQ

What is the current stock price of vTv Therapeutics (VTVT)?

The current stock price of vTv Therapeutics (VTVT) is $14.96 as of December 20, 2024.

What is the market cap of vTv Therapeutics (VTVT)?

The market cap of vTv Therapeutics (VTVT) is approximately 37.9M.

What is the main focus of vTv Therapeutics Inc.?

vTv Therapeutics Inc. is focused on developing orally administered treatments for metabolic and inflammatory diseases to address unmet medical needs.

What is cadisegliatin (TTP399)?

Cadisegliatin (TTP399) is an investigational liver-selective glucokinase activator being developed as an adjunctive therapy to insulin for type 1 diabetes (T1D).

What are some other drug candidates in vTv Therapeutics' pipeline?

Other candidates include TTP273, HPP737, HPP593, azeliragon, HPP971, HPP3033, and TTP-RA.

What is the partnership between vTv Therapeutics and Reneo Pharmaceuticals?

vTv granted Reneo an exclusive worldwide license for its PPARδ agonist program, including potential milestone payments and commercial royalties.

What recent financial moves has vTv Therapeutics made?

vTv raised funds through a private investment in public equity (PIPE) to support the Phase 3 study of cadisegliatin.

When is the Phase 3 trial for cadisegliatin expected to start?

The Phase 3 study for cadisegliatin is expected to initiate in mid-2024.

What other conditions are being targeted by vTv's development partners?

Additional indications include type 2 diabetes, chronic obstructive pulmonary disease, primary mitochondrial myopathy, and various cancers.

What are the potential benefits of the cadisegliatin therapy?

Cadisegliatin aims to reduce hypoglycemic episodes in type 1 diabetes patients, potentially improving glycemic control and quality of life.

What is azeliragon, and who is developing it?

Azeliragon is an orally administered capsule targeting glioblastoma and pancreatic cancer, developed by Cantex Pharmaceuticals under license from vTv.

How does vTv Therapeutics plan to use the proceeds from recent investments?

The proceeds will be used to fund the first Phase 3 study of cadisegliatin and support other research and development activities.

vTv Therapeutics Inc.

Nasdaq:VTVT

VTVT Rankings

VTVT Stock Data

37.93M
1.66M
38.82%
14.95%
1.19%
Biotechnology
Pharmaceutical Preparations
Link
United States of America
HIGH POINT