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Spruce Biosciences, Inc. - SPRB STOCK NEWS

Welcome to our dedicated page for Spruce Biosciences news (Ticker: SPRB), a resource for investors and traders seeking the latest updates and insights on Spruce Biosciences stock.

Spruce Biosciences, Inc. (NASDAQ: SPRB) is a clinical-stage biopharmaceutical company dedicated to pioneering new therapies for rare endocrine disorders. The company's mission is to develop and commercialize novel treatments that address unmet medical needs within this specialized field.

Spruce Biosciences is currently advancing its primary product candidate, tildacerfont. This innovative therapy is being developed to serve as the first non-steroidal treatment designed to significantly improve disease management and lessen the dependency on steroids for patients with classic congenital adrenal hyperplasia (CAH). CAH is a genetic disorder affecting the adrenal glands, leading to an imbalance in hormone production. Tildacerfont aims to address this imbalance, offering a promising alternative for patients who have limited treatment options.

The company has made notable strides in its development programs, with ongoing clinical trials aiming to demonstrate the efficacy and safety of tildacerfont. These efforts are crucial in pushing the boundaries of current endocrine disorder treatments and providing new hope for those affected by these rare conditions.

In addition to its flagship product, Spruce Biosciences actively explores other potential therapies and partnerships to expand its impact in the field of endocrinology. The company’s financial health is supported by strategic investments and collaborations, ensuring robust progress towards its goals.

Spruce Biosciences’ commitment to addressing rare endocrine diseases positions it as a significant player in the biopharmaceutical industry. With a clear focus on innovation and patient care, the company continues to make meaningful advancements in medical science. Stay updated with the latest developments from Spruce Biosciences to learn more about its ongoing projects and clinical trials.

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Spruce Biosciences (Nasdaq: SPRB), a biopharmaceutical company, reported its Q1 2024 financial results and provided corporate updates. Key highlights include a 45% reduction in ACTH in the CAHmelia-203 study, correlating higher baseline GC doses and drug compliance with better outcomes. The company anticipates topline data from CAHmelia-204 and CAHptain-205 in Q3 2024. Financially, Spruce reported $81.2 million in cash reserves, $2 million in collaboration revenue, and a net loss of $11.6 million, improving from $12.8 million YoY. R&D expenses decreased to $10.3 million, while G&A expenses rose to $4.3 million. Total operating expenses were $14.6 million, down from $15.2 million a year ago. Upcoming milestones include Phase 2 data and an FDA meeting in early 2025.

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Spruce Biosciences, Inc. (Nasdaq: SPRB) will participate in two upcoming investor conferences in May, featuring Fireside chats and 1x1 meetings. The events will include the JMP Securities Life Sciences Conference on May 13-14, 2024, and the RBC Capital Markets Global Healthcare Conference on May 14-15, 2024. The CEO, Javier Szwarcberg, M.D., M.P.H., will be presenting at these conferences, with webcasts available on the company's investor relations website.

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Spruce Biosciences, Inc. announced additional poster presentations at the Pediatric Endocrine Society 2024 Annual Meeting, highlighting baseline characteristics of their CAHptain program for children with congenital adrenal hyperplasia (CAH) and the CAHmelia program for adults with CAH. The company is focused on developing therapies for rare endocrine disorders and will present abstracts at the conference in Chicago, IL.

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Spruce Biosciences (Nasdaq: SPRB) is set to present baseline characteristics of its CAHmelia program at the Pediatric Endocrine Society 2024 Annual Meeting, highlighting tildacerfont in adult congenital adrenal hyperplasia management. The presentation aims to address unmet medical needs in pediatric CAH.
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Spruce Biosciences, Inc. (SPRB) reports financial results for 2023, highlighting positive data from CAHptain-205 study in pediatric classic CAH and challenges faced in CAHmelia-203 study for adult classic CAH. The company plans to meet regulatory authorities in 2025 for a registrational clinical program. Cost reductions extend cash runway through 2025.
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Spruce Biosciences, Inc. (Nasdaq: SPRB) announced topline results from its CAHmelia-203 and CAHptain-205 studies of tildacerfont in adult and pediatric classic congenital adrenal hyperplasia (CAH). While CAHmelia-203 did not meet its primary efficacy endpoint, CAHptain-205 showed promising results. The company plans to meet regulatory authorities for a potential registrational program.
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Spruce Biosciences, Inc. (SPRB) will present at the Oppenheimer 34th Annual Healthcare Life Sciences Conference on February 13, 2024. The CEO will discuss the development and commercialization of novel therapies for rare endocrine disorders. The live webcast can be accessed on the company's investor relations website, with an archived copy available for 90 days.
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Spruce Biosciences, Inc. (Nasdaq: SPRB) has completed enrollment in its CAHmelia-204 clinical trial of tildacerfont for the treatment of adult classic congenital adrenal hyperplasia (CAH), enrolling 100 patients, exceeding the target of 90. The company anticipates reporting topline results in the third quarter of 2024, with plans to meet with regulatory authorities to discuss the potential registrational path forward for tildacerfont. CAHmelia-204 is a randomized, double-blind, placebo-controlled clinical trial evaluating the safety and efficacy of tildacerfont in reducing glucocorticoid usage in adults with classic CAH.
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Spruce Biosciences, Inc. (SPRB) reported baseline characteristics of patients enrolled in the CAHmelia-203 and CAHmelia-204 clinical studies of tildacerfont for the treatment of adult classic congenital adrenal hyperplasia (CAH). The company's CEO, Javier Szwarcberg, highlighted the significance of hyperandrogenemia and hypercortisolemia within this patient population. Patients in CAHmelia-203 enrolled with mean baseline A4 levels nearly six times above the upper limit of normal on a mean baseline daily glucocorticoid (GC) dose of 27 mg hydrocortisone equivalents (HCe). On the other hand, patients in CAHmelia-204 enrolled with a mean baseline daily GC dose of 35 mg HCe and suppressed levels of A4. Spruce Biosciences looks forward to reporting topline results from CAHmelia-203 in March, followed by CAHmelia-204 in the third quarter.
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Spruce Biosciences, a late-stage biopharmaceutical company (Nasdaq: SPRB), is making significant progress in developing novel therapies for rare endocrine disorders, with upcoming milestones including topline results from CAHmelia-203 and CAHptain-205 in March 2024, and from CAHmelia-204 in Q3 2024. The company also anticipates maintaining cash runway into the first half of 2025.
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FAQ

What is the current stock price of Spruce Biosciences (SPRB)?

The current stock price of Spruce Biosciences (SPRB) is $0.4 as of December 20, 2024.

What is the market cap of Spruce Biosciences (SPRB)?

The market cap of Spruce Biosciences (SPRB) is approximately 15.7M.

What is Spruce Biosciences, Inc. focused on?

Spruce Biosciences is focused on developing and commercializing novel therapies for rare endocrine disorders with unmet medical needs.

What is tildacerfont?

Tildacerfont is Spruce Biosciences' lead product candidate, developed as the first non-steroidal therapy to improve disease control and reduce steroid dependency for patients with classic congenital adrenal hyperplasia (CAH).

What are classic congenital adrenal hyperplasia (CAH) and its symptoms?

Classic congenital adrenal hyperplasia (CAH) is a genetic disorder that affects adrenal gland function, leading to hormone imbalances. Symptoms may include abnormal growth patterns, early puberty, and severe acne.

How is Spruce Biosciences contributing to medical science?

Spruce Biosciences contributes by developing innovative treatments for rare endocrine disorders, conducting clinical trials, and aiming to improve patient outcomes.

What is the significance of tildacerfont in treating CAH?

Tildacerfont is significant because it could offer the first non-steroidal treatment option for CAH, reducing steroid burden and providing better disease control for patients.

Are there ongoing clinical trials for tildacerfont?

Yes, Spruce Biosciences is conducting clinical trials to evaluate the safety and efficacy of tildacerfont in treating patients with CAH.

How does Spruce Biosciences support its financial health?

The company’s financial health is supported by strategic investments and collaborations, which help fund its development programs and clinical trials.

What partnerships does Spruce Biosciences have?

Spruce Biosciences engages in various partnerships to bolster its research and development initiatives, although specific partners are not mentioned in this description.

Where can I find the latest news about Spruce Biosciences?

You can find the latest news and updates about Spruce Biosciences on their official website and other reputable financial news platforms.

What makes Spruce Biosciences a significant player in its industry?

Spruce Biosciences is significant due to its focus on addressing rare endocrine disorders with unmet medical needs, innovative product development, and commitment to improving patient care.

Spruce Biosciences, Inc.

Nasdaq:SPRB

SPRB Rankings

SPRB Stock Data

15.70M
36.96M
10.51%
46.69%
0.17%
Biotechnology
Pharmaceutical Preparations
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United States of America
SOUTH SAN FRANCISCO