Welcome to our dedicated page for Sensei Biotherapeutics news (Ticker: SNSE), a resource for investors and traders seeking the latest updates and insights on Sensei Biotherapeutics stock.
Sensei Biotherapeutics, Inc. develops clinical-stage cancer therapeutics focused on multi-node inhibition of oncogenic pathways. Its lead program, PIKTOR, is an investigational all-oral combination of serabelisib and sapanisertib designed to target PI3K-alpha and dual mTORC1/2 nodes in the PI3K/AKT/mTOR pathway for endometrial and breast cancer. The company also reports on solnerstotug, a V-domain Ig suppressor of T cell activation, or VISTA, inhibitor for advanced solid tumors.
Recurring company news includes oncology trial activity, clinical and regulatory disclosures, operating and financial results, governance updates, capital-structure matters, and Nasdaq inducement equity grants tied to employee compensation.
Sensei Biotherapeutics (NASDAQ: SNSE) has reported promising preliminary results from its Phase 1/2 trial of solnerstotug, a conditionally active antibody targeting VISTA. The drug showed significant clinical activity in PD-(L)1 resistant tumors, achieving a 14% overall response rate - nearly triple the historical rechallenge rates of ≤5%.
Key findings include:
- One durable complete response in Merkel Cell Carcinoma (MCC)
- Two partial responses in MCC and MSI-H Colorectal Cancer patients
- 62% disease control rate among 21 evaluable PD-(L)1 resistant patients
- All patients with tumor shrinkage remain on treatment
The drug demonstrated favorable safety with no dose-limiting toxicities, mostly Grade 1-2 adverse events, and only 7% cases of mild cytokine release syndrome. Subject to capital raising, Sensei plans to initiate Phase 2 studies in Q1 2026.
Sensei Biotherapeutics (Nasdaq: SNSE), a clinical stage biotechnology company specializing in next-generation cancer therapeutics, has announced its participation in Oppenheimer's 35th Annual Healthcare Life Sciences Conference. The company's President and CEO, John Celebi, will deliver a presentation at the virtual event on Tuesday, February 11, 2025, at 10:40 a.m. ET.
Interested parties can access the presentation webcast through the Investors section of Sensei's website. The replay will remain available for approximately 90 days after the event, and registration for the webcast is currently open.
Sensei Biotherapeutics (NASDAQ: SNSE) provided updates on its lead program, solnerstotug (SNS-101), a conditionally active antibody targeting VISTA in cancer treatment. The company has enrolled 45 patients in the dose expansion portion of its Phase 1/2 clinical trial, with full enrollment of approximately 60 patients expected by Q1 2025.
The trial evaluates solnerstotug both as monotherapy and in combination with Libtayo® in patients with advanced solid tumors. Most enrolled 'hot' tumor patients have either progressed on prior anti-PD-1 therapy or are PD-L1 negative. The drug continues to show good tolerability with a best-in-class pharmacokinetic profile, with dose optimization focusing on 3 and 15 mg/kg Q3W levels.
Clinical data update is expected in Q2 2025, including patient follow-up data from dose escalation cohorts. The company maintains cash runway into Q2 2026.
Sensei Biotherapeutics (Nasdaq: SNSE) announced its participation in Citi's 2024 Global Healthcare Conference. The conference will take place from December 3-5 in Miami, FL. As a clinical stage biotechnology company specializing in next-generation cancer therapeutics, Sensei's management team will be present at this significant healthcare industry event.
Sensei Biotherapeutics (NASDAQ: SNSE) reported Q3 2024 financial results and announced an organizational restructuring. The company will reduce its workforce by 46% and close its Rockville research site to focus resources on SNS-101 clinical development. Cash position stands at $47.0 million, expected to fund operations into Q2 2026. Q3 net loss was $7.3 million, with R&D expenses at $4.6 million and G&A expenses at $3.2 million. The Phase 1/2 dose expansion study for SNS-101 is approximately 50% enrolled, with clinical data expected in H1 2025.
Sensei Biotherapeutics (Nasdaq: SNSE) has announced its participation in two major scientific conferences. At PEGS Europe in Barcelona (November 5-7, 2024), Chief Scientific Officer Edward van der Horst will present on SNS-101, a conditionally active monoclonal antibody targeting VISTA in tumor microenvironment. At the SITC 39th Annual Meeting in Houston (November 6-10, 2024), Senior Director F. Donelson Smith will present a poster on spatial proteomic profiling of VISTA and PSGL-1 interactions across cancer indications.
Sensei Biotherapeutics (Nasdaq: SNSE) announced that it will present preclinical data on SNS-103 at the CRI-ENCI Eighth International Immunotherapy Conference from September 8-11, 2024. The presentation, titled 'Pre-clinical characterization of monoclonal antibodies targeting CD39 activity in the acidic tumor microenvironment,' will be given by F. Donelson Smith, Ph.D., Senior Director of Biologics Discovery & Early Development. The poster session is scheduled for September 8, 2024, from 12:05 – 2:05 p.m. EDT.
Sensei Biotherapeutics is a clinical-stage immuno-oncology company focused on developing next-generation cancer therapeutics. The presentation of preclinical data on SNS-103 suggests ongoing research and development efforts in their pipeline.
Sensei Biotherapeutics (Nasdaq: SNSE), a clinical stage immuno-oncology company, has announced its participation in two upcoming conferences in September 2024. The company will present at the H.C. Wainwright 26th Annual Global Investment Conference on September 9 at 7:00 a.m. ET, delivering a corporate presentation. Additionally, Sensei will participate in a fireside chat at the 2024 Cantor Fitzgerald Global Healthcare Conference on September 18 at 2:30 p.m. ET.
Both events will be accessible via webcast on the Investors section of Sensei's website, with replays available for approximately 90 days following the presentations. These conferences provide Sensei Biotherapeutics with opportunities to showcase their progress in developing next-generation cancer therapeutics to investors and industry professionals.
Sensei Biotherapeutics (Nasdaq: SNSE) reported Q2 2024 financial results and business highlights. The company presented promising Phase 1/2 clinical data for SNS-101 at ASCO 2024, demonstrating early signs of clinical activity in immunotherapy-resistant patients. Patient enrollment is advancing in the dose expansion portion of the Phase 1/2 study, with initial data expected in Q4 2024. Sensei's cash position stands at $52.3 million, providing runway into Q4 2025. Financial results show R&D expenses of $4.6 million and G&A expenses of $3.2 million for Q2 2024. The company reported a net loss of $7.1 million, an improvement from $9.4 million in Q2 2023.
Sensei Biotherapeutics, a clinical stage immuno-oncology company, announced its participation in the Jefferies Global Healthcare Conference. The event will take place in New York on June 6, 2024, at 8:30 a.m. ET. John Celebi, President and CEO, is set to present. The presentation will be webcast live on the investors section of Sensei's website, with a replay available for 90 days.