Welcome to our dedicated page for Sana Biotechnology news (Ticker: SANA), a resource for investors and traders seeking the latest updates and insights on Sana Biotechnology stock.
Sana Biotechnology, Inc. (NASDAQ: SANA) is a cutting-edge biotechnology company dedicated to the development of engineered cells as medicines to treat various diseases. Sana's primary focus is on cell and gene therapy, aiming to harness the potential of engineered cells to bring about transformative changes in healthcare.
The company is advancing a range of innovative therapeutic programs across multiple indications with unmet medical needs. Some of the key areas of focus include oncology, diabetes, B-cell-mediated autoimmune disorders, and central nervous system (CNS) disorders. Sana's pipeline includes promising candidates such as SC291, SC262, SC255, and UP421, which are at various stages of development.
Recent Achievements and Projects:
- Hypoimmune Technology: Sana's proprietary hypoimmune (HIP) platform is designed to create cells that can evade the patient’s immune system, allowing for the transplant of allogeneic cells without the need for immunosuppression.
- CAR T Cell Therapies: The company is developing novel CAR T cell therapies for various cancers and autoimmune diseases. Preclinical data have shown that HIP-modified CAR T cells can avoid immune detection while retaining their functionality and anti-tumor effects.
- Pluripotent Stem Cells: Sana is also focused on differentiating pluripotent stem cells ex vivo into immune-cloaked functional cells, aiming to replace any missing or damaged cells in the body.
- Preclinical and Clinical Studies: In recent studies, Sana has demonstrated significant progress, such as the successful evasion of immune detection by HIP-modified CAR T cells and the potential for HIP-modified pancreatic islet cells to achieve insulin independence in diabetic models.
- Partnerships: The company collaborates with leading research institutions and organizations to further its mission of developing next-generation cell and gene therapies.
Sana Biotechnology operates out of multiple locations, including Seattle, Cambridge, South San Francisco, and Rochester, and is committed to advancing its pipeline of therapies to address critical healthcare challenges.
Generate Biomedicines has raised $370 million in a Series B financing to enhance its machine learning-powered Generative Biology platform, aimed at drug development across various protein modalities. This funding will facilitate technology evolution, organizational scaling from 80 to 500 employees, and the establishment of new facilities for computational biology and data generation. The company plans to advance several preclinical programs by year-end 2023, showcasing its pioneering efforts in programmable biotherapeutics.
Sana Biotechnology reported a net loss of $83.3 million for Q3 2021, translating to $0.46 per share, significantly higher than the $51.5 million loss ($3.76 per share) in Q3 2020. The company secured a cash position of $866.1 million, bolstered by $626.4 million from its IPO earlier in the year. Research and development expenses rose to $53.2 million, driven by increased personnel and operational costs. A notable development includes a license agreement with Beam for CRISPR technology, aimed at enhancing Sana's engineered cell therapy pipeline.
Sana Biotechnology (NASDAQ: SANA) announced plans to present data during four poster presentations at the 63rd American Society of Hematology Annual Meeting, taking place from December 11 to December 14, 2021. This event will highlight advancements in Sana's engineered cell therapies, specifically focusing on in vivo CAR T and ex vivo allogeneic CAR T cell programs. CEO Steve Harr expressed excitement over these scientific developments, emphasizing the company’s goal to file its first IND application as early as next year. The abstracts are available online, with full presentations scheduled throughout the event.
Tessera Therapeutics has announced a collaboration with the Cystic Fibrosis Foundation to utilize its Gene Writing technology for developing treatments for cystic fibrosis. This innovative technology aims to correct genetic mutations causing the disease, which affects around 70,000 people worldwide. The partnership seeks to advance Gene Writers capable of making specific genetic corrections and introducing a functional CFTR gene, targeting a major mutation responsible for 70% of cases. This collaboration may pave the way for groundbreaking therapies in cystic fibrosis treatment.
Sana Biotechnology, Inc. (NASDAQ: SANA) announced a non-exclusive licensing agreement with Beam Therapeutics (NASDAQ: BEAM) for the use of Beam's CRISPR Cas12b nuclease system in Sana's ex vivo engineered cell therapy programs. This agreement allows Sana to utilize the Cas12b system in developing allogeneic T cell and stem cell-derived therapies, with a focus on gene editing for its hypoimmune platform. Sana will make an upfront payment of $50 million to Beam, along with potential milestone and royalty payments based on sales of resulting products.
Sana Biotechnology (NASDAQ: SANA) will present at the Morgan Stanley 19th Annual Global Healthcare Conference on September 13, 2021, at 2:00 p.m. PT. The presentation, hosted by CEO Steve Harr, will offer insights into the company's business and updates on its innovative approaches in engineered cell therapies. Interested parties can access the live webcast on Sana's Investor Relations page, with a replay available for 30 days post-conference. Sana aims to revolutionize medicine through gene repair and cell replacement, employing a dynamic team of over 320 professionals across Seattle, Cambridge, and South San Francisco.
MaxCyte has signed a clinical and commercial license agreement with Sana Biotechnology, granting Sana the rights to use MaxCyte's Flow Electroporation® technology and ExPERT™ platform. In return, MaxCyte will receive licensing fees and milestone payments. Doug Doerfler, MaxCyte's CEO, expressed enthusiasm for supporting Sana's cell therapy programs, highlighting the potential of Sana's hypoimmune cell platform. This collaboration aims to enhance the development of innovative cell-based treatments, reinforcing MaxCyte's position in the biopharmaceutical sector.
Sana Biotechnology reported its Q2 2021 results, highlighting a cash position of $930.8 million, significantly up from $412.0 million in Q4 2020. The company presented data showing immune evasion in transplanted hypoimmune cells in primates without immunosuppression, advancing its engineered cell therapies. A long-term lease was signed for a 163,000 square foot manufacturing facility in Fremont, California, to support clinical and commercial products. The net income for Q2 was $18.7 million, representing $0.10 per share, while the net loss for the first half was $161.9 million, or $1.08 per share.
Sana Biotechnology (NASDAQ: SANA) has announced plans to develop a new 163,000 square foot manufacturing facility in Fremont, California. This facility aims to support late-stage clinical development and early commercial product candidates. CEO Steve Harr emphasized that this facility is crucial for addressing manufacturing challenges in cell and gene therapies. The new site will enhance Sana's capabilities in producing allogeneic T cells, viral vectors, and pluripotent stem cells while maintaining proximity to existing technical expertise and a strong biotech workforce.
Sana Biotechnology, Inc. (NASDAQ: SANA) will present significant data at the International Society for Stem Cell Research 2021 Virtual Annual Meeting from June 21-26. Chuck Murry, M.D., will discuss 'Genome Editing to Eliminate Engraftment Arrhythmia' on June 21, while Sonja Schrepfer, M.D., will present on immune protection of transplanted stem cells on June 26. Both presentations will be available for on-demand viewing through July 31. Sana aims to advance engineered cells as medicines for various diseases, supported by a dedicated team across multiple locations.
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