Sana Biotechnology, Inc. Stock Price, News & Analysis

Cellarity has announced key appointments to its executive team, enhancing its expertise in drug development. Laurens Kruidenier, Ph.D., joins as Chief Scientific Officer to lead drug platform evolution, while Anna O’Driscoll becomes Chief People Officer to drive talent development. Parul Doshi is appointed Senior VP, Head of Data and Software Engineering to bolster data infrastructure. These changes underscore Cellarity's commitment to advancing its drug creation process, particularly its unique approach that examines cellular changes underlying diseases, applicable across multiple therapeutic areas.

Sana Biotechnology (NASDAQ: SANA) has secured an exclusive worldwide license from the National Cancer Institute for the CD22 chimeric antigen receptor (CAR) technology. This agreement focuses on enhancing engineered T cell therapies for B cell malignancies, particularly addressing relapse challenges associated with current CD19-directed CAR therapies. With promising clinical data supporting the efficacy of CD22 CAR, Sana aims to improve outcomes for patients suffering from B cell malignancies, including non-Hodgkin lymphoma and acute lymphoblastic leukemia. Financial terms include upfront payments, milestone payments, and royalties on sales.

Sana Biotechnology has entered an agreement with IASO Biotherapeutics and Innovent Biologics to obtain non-exclusive commercial rights to a clinically validated BCMA CAR construct. This construct, part of an autologous CAR T cell therapy, has shown promising results for treating relapsed/refractory multiple myeloma, with a 94.9% overall response rate reported in clinical trials. The deal includes an upfront payment and potential milestone payments totaling up to $204 million.

Sana Biotechnology, Inc. (NASDAQ: SANA) will webcast its presentation at the 40th Annual J.P. Morgan Healthcare Conference on January 11, 2022, at 10:30 a.m. PT. The presentation, led by President and CEO Steve Harr, will provide a business overview and update. Interested investors can access the webcast on Sana's Investor Relations webpage, where a replay will be available for 30 days post-conference. Sana focuses on developing engineered cell therapies to treat diseases, aiming to repair genes and replace damaged cells.

Sana Biotechnology (NASDAQ: SANA) presented advancements at the 63rd ASH Annual Meeting. Notable highlights include data on hypoimmune CAR T cells that evade immune response in murine models and the use of fusosome technology for T cell delivery. Key presentations showed the effectiveness of hypoimmune CAR T cells against leukemia, and the capability of fusosomes to transduce T helper cells into CAR T cells. The company aims to file INDs for clinical trials in the upcoming year, signaling progression in their CAR T cell programs.

Generate Biomedicines has raised $370 million in a Series B financing to enhance its machine learning-powered Generative Biology platform, aimed at drug development across various protein modalities. This funding will facilitate technology evolution, organizational scaling from 80 to 500 employees, and the establishment of new facilities for computational biology and data generation. The company plans to advance several preclinical programs by year-end 2023, showcasing its pioneering efforts in programmable biotherapeutics.

Sana Biotechnology reported a net loss of $83.3 million for Q3 2021, translating to $0.46 per share, significantly higher than the $51.5 million loss ($3.76 per share) in Q3 2020. The company secured a cash position of $866.1 million, bolstered by $626.4 million from its IPO earlier in the year. Research and development expenses rose to $53.2 million, driven by increased personnel and operational costs. A notable development includes a license agreement with Beam for CRISPR technology, aimed at enhancing Sana's engineered cell therapy pipeline.

Sana Biotechnology (NASDAQ: SANA) announced plans to present data during four poster presentations at the 63rd American Society of Hematology Annual Meeting, taking place from December 11 to December 14, 2021. This event will highlight advancements in Sana's engineered cell therapies, specifically focusing on in vivo CAR T and ex vivo allogeneic CAR T cell programs. CEO Steve Harr expressed excitement over these scientific developments, emphasizing the company’s goal to file its first IND application as early as next year. The abstracts are available online, with full presentations scheduled throughout the event.

Tessera Therapeutics has announced a collaboration with the Cystic Fibrosis Foundation to utilize its Gene Writing technology for developing treatments for cystic fibrosis. This innovative technology aims to correct genetic mutations causing the disease, which affects around 70,000 people worldwide. The partnership seeks to advance Gene Writers capable of making specific genetic corrections and introducing a functional CFTR gene, targeting a major mutation responsible for 70% of cases. This collaboration may pave the way for groundbreaking therapies in cystic fibrosis treatment.