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Phio Pharmaceuticals Corp. - PHIO STOCK NEWS

Welcome to our dedicated page for Phio Pharmaceuticals news (Ticker: PHIO), a resource for investors and traders seeking the latest updates and insights on Phio Pharmaceuticals stock.

Phio Pharmaceuticals Corp. (Nasdaq: PHIO), headquartered in Marlborough, Massachusetts, is a clinical-stage biotechnology company focused on developing innovative immuno-oncology therapeutics. The company's proprietary INTASYL™ siRNA gene silencing technology is at the forefront of its efforts to enhance the effectiveness of immune cells in targeting and destroying tumor cells.

Phio's core product pipeline includes:

  • PH-762: Targets the checkpoint protein PD-1 on immune cells, enhancing their ability to attack tumors. Currently in Phase 1b clinical trials, PH-762 is being tested for its efficacy in treating cutaneous squamous cell carcinoma, melanoma, and Merkel cell carcinoma.
  • PH-804: Focuses on the suppressive immune receptor TIGIT, present on T cells and natural killer cells, to bolster immune responses against cancer.
  • PH-790: Aims to silence the PD-L1 protein, which normally prevents immune cells from attacking non-harmful cells, thereby boosting the body's natural defenses against cancer.

Phio Pharmaceuticals collaborates with leading institutions such as Gustave Roussy, Medigene AG, and Helmholtz Zentrum München to advance their research and development efforts. The company's financial health, as of the latest reports, shows a cash position of $6.5 million, with a significant reduction in research and development expenses aimed at transitioning from discovery to product development.

Phio's latest updates include the presentation of new data on PH-762 at various scientific conferences and the initiation of new partnerships. These efforts underscore Phio's commitment to delivering cutting-edge cancer treatments and improving patient outcomes.

For more details, visit the company's website at www.phiopharma.com.

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Phio Pharmaceuticals Corp. (Nasdaq: PHIO) announces the exercise of warrants by accredited investors, expected to generate approximately $2.8 million in gross proceeds.
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Phio Pharmaceuticals Corp. (Nasdaq: PHIO) reports Q3 financial results and business update, enrolling first patient in US clinical trial for PH-762, a novel immuno-oncology therapy for skin cancers.
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Phio Pharmaceuticals Corp. (Nasdaq: PHIO) announced the dosing of the first patient in the Phase 1b clinical trial of PH-762, an INTASYL compound that reduces the expression of PD-1, a protein that inhibits T cells’ ability to kill cancer cells. The trial aims to evaluate the safety and tolerability of neoadjuvant use of intratumorally injected PH-762 and assess the tumor response in patients with cutaneous squamous cell carcinoma, melanoma, or Merkel cell carcinoma.
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Phio Pharmaceuticals Corp. announced new preclinical data at the 38th Annual Meeting of the Society for Immunotherapy of Cancer. The data highlights the benefit of combining their INTASYL compound targeting CTLA-4 with systemic anti-PD-1 antibody therapy. The combination significantly enhanced the efficacy of anti-PD-1 therapy, leading to complete regression of around 40% of treated tumors in a mouse model. The INTASYL compound also improved the efficacy of anti-PD-1 therapy on tumors not directly treated with the compound. Additionally, it increased the percentage of reactive CD8+ T cells while decreasing immunosuppressive macrophages in the tumor micro-environment.
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Phio Pharmaceuticals to present new preclinical data at SITC Annual Meeting
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Phio Pharmaceuticals presents preclinical data on INTASYL compound PH-894 at AACR-NCI-EORTC Conference
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Phio Pharmaceuticals CEO to present at H.C. Wainwright Conference, discussing FDA IND approvals for lead product PH-762 and new leadership team
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Phio Pharmaceuticals announces first patient dosed in Adoptive Cell Therapy trial for metastatic melanoma and solid tumors
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Phio Pharmaceuticals reports Q2 2023 financial results and provides business update
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FAQ

What is the current stock price of Phio Pharmaceuticals (PHIO)?

The current stock price of Phio Pharmaceuticals (PHIO) is $2.552 as of November 19, 2024.

What is the market cap of Phio Pharmaceuticals (PHIO)?

The market cap of Phio Pharmaceuticals (PHIO) is approximately 2.2M.

What does Phio Pharmaceuticals Corp. do?

Phio Pharmaceuticals Corp. develops immuno-oncology therapeutics to enhance the effectiveness of immune cells in killing tumor cells using its proprietary INTASYL™ siRNA gene silencing technology.

What is INTASYL™ technology?

INTASYL™ is Phio Pharmaceuticals' proprietary self-delivering RNAi technology designed to target specific proteins that inhibit the body's immune response against cancer, without the need for specialized formulations or delivery systems.

What are Phio's key products?

Phio's key products include PH-762, targeting PD-1; PH-804, targeting TIGIT; and PH-790, targeting PD-L1, all aimed at boosting the immune system’s ability to combat cancer.

Who are Phio's collaboration partners?

Phio collaborates with notable institutions such as Gustave Roussy, Medigene AG, and Helmholtz Zentrum München.

What recent achievements has Phio Pharmaceuticals announced?

Recent achievements include the presentation of new data on PH-762, progress in clinical trials, and new partnerships aimed at advancing their immuno-oncology programs.

What is the financial condition of Phio Pharmaceuticals?

As of the latest reports, Phio Pharmaceuticals has a cash position of $6.5 million. The company has reduced research and development expenses to focus on transitioning from discovery to product development.

What is PH-762?

PH-762 is an INTASYL compound that targets the PD-1 protein on immune cells, enhancing their ability to attack cancer cells. It is currently in Phase 1b clinical trials.

What cancers is PH-762 being tested for?

PH-762 is being tested for cutaneous squamous cell carcinoma, melanoma, and Merkel cell carcinoma in its Phase 1b clinical trials.

What is the significance of INTASYL™ technology?

INTASYL™ technology is significant because it allows for precise targeting of proteins that reduce the body's ability to fight cancer, improving the effectiveness of immune cells without the need for specialized drug delivery systems.

Where can I find more information about Phio Pharmaceuticals?

For more information, you can visit Phio Pharmaceuticals' official website at www.phiopharma.com.

Phio Pharmaceuticals Corp.

Nasdaq:PHIO

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2.16M
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Biotechnology
Pharmaceutical Preparations
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United States of America
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