Welcome to our dedicated page for Intellia Therapeutics news (Ticker: NTLA), a resource for investors and traders seeking the latest updates and insights on Intellia Therapeutics stock.
Intellia Therapeutics, Inc. (NASDAQ: NTLA) is a pioneering clinical-stage gene editing company dedicated to revolutionizing medicine through the use of CRISPR-based therapies. Founded in 2014 by Caribou Biosciences and Atlas Venture, along with leading scientists in the field, Intellia harnesses the potential of CRISPR/Cas9 technology to develop curative treatments for a variety of genetically defined diseases.
The company's core mission is to leverage CRISPR/Cas9—an innovative technology adapted from a natural cellular process that allows for precise and flexible gene editing. This technology enables the correction of specific DNA sequences within any organism, opening new frontiers in biomedical research and clinical interventions.
Intellia's portfolio includes both in vivo and ex vivo gene editing programs. The in vivo programs aim to edit disease-causing genes directly within the human body, targeting conditions such as ATTR amyloidosis, hereditary angioedema (HAE), and alpha-1 antitrypsin deficiency. Notable achievements include the interim results from their NTLA-2002 program for HAE, which showed a 95% reduction in monthly attack rates, with most patients remaining attack-free.
The ex vivo programs focus on engineering human cells outside the body to treat cancer and autoimmune diseases. These programs include collaborations with prominent companies like Regeneron and Novartis, which help advance their therapeutic pipeline.
Intellia's financial condition reflects its robust pipeline and strategic partnerships. The company recently reported strong enrollment progress in their pivotal Phase 3 MAGNITUDE trial for NTLA-2001 targeted at ATTR amyloidosis with cardiomyopathy. They have also formed a strategic collaboration with ReCode Therapeutics to develop treatments for cystic fibrosis, utilizing ReCode's Selective Organ Targeting (SORT) lipid nanoparticle delivery platform.
Committed to advancing the field of gene editing, Intellia continues to expand its CRISPR-based platform with novel editing and delivery technologies. The company remains at the forefront of a new era in medicine, as evidenced by its ongoing clinical trials and promising preliminary data.
For more detailed information and the latest updates, investors and stakeholders are encouraged to visit www.intelliatx.com and follow Intellia on Twitter @intelliatx.
Intellia Therapeutics' co-founder, Dr. Jennifer Doudna, has been awarded the 2020 Nobel Prize in Chemistry for her role in developing the CRISPR/Cas9 genome editing technology, alongside Dr. Emmanuelle Charpentier. This milestone marks the first instance of two women jointly winning this accolade in Chemistry. Intellia’s leadership highlighted the transformative potential of CRISPR/Cas9 in addressing genetic diseases and cancer. The company underscores its commitment to utilizing this groundbreaking tool to develop enduring therapeutic solutions for complex health conditions.
Intellia Therapeutics (NASDAQ: NTLA) has appointed John F. Crowley to its Board of Directors, bringing extensive biotech experience, particularly in rare diseases. Crowley, CEO of Amicus Therapeutics, has a strong track record in transitioning programs from preclinical to clinical stages. His insights as a parent advocate for Pompe disease will be valuable as Intellia embarks on its first clinical trial this year. Meanwhile, Perry Karsen will step down from the board effective December 31, 2020, after five years of significant contributions to the company's growth.
Intellia Therapeutics (NASDAQ: NTLA) will present at Baird’s 2020 Virtual Global Healthcare Conference on September 9, 2020, at 10:50 a.m. ET. The presentation will showcase the company's advancements in CRISPR/Cas9 technology aimed at developing curative therapeutics. A live webcast can be accessed on the company's website, with a replay available for 14 days post-event. Intellia focuses on editing disease-associated genes to treat cancer and immunological diseases, positioning itself as a leader in genome editing.
Intellia Therapeutics (NTLA) has submitted its first regulatory application to the U.K.’s MHRA for a Phase 1 study of NTLA-2001, targeting transthyretin amyloidosis, aiming to dose the first patient by year-end. The company expanded its collaboration with Regeneron, receiving $100 million to co-develop hemophilia treatments. Intellia plans to submit INDs for NTLA-5001 (acute myeloid leukemia) and NTLA-2002 (hereditary angioedema) in 2021. As of June 30, 2020, the company reported a cash position of $436.8 million, enabling operations for at least 24 months.
Intellia Therapeutics (NASDAQ: NTLA) will present its second quarter 2020 financial results and operational highlights in a conference call scheduled for August 6, 2020, at 8 a.m. ET. The company, a frontrunner in genome editing using CRISPR/Cas9 technology, aims to develop curative therapeutics both in vivo and ex vivo. Interested participants can join the call by dialing the provided numbers or access a replay on the company's website later that day. Intellia's commitment to advancing CRISPR technology positions it for significant therapeutic applications.
Intellia Therapeutics (NTLA) has successfully completed an underwritten public offering of 6,301,370 shares at $18.25 per share, raising approximately $115 million in gross proceeds. The offering included the full exercise of an option for an additional 821,917 shares. Goldman Sachs, Jefferies, and SVB Leerink served as joint book-running managers. The shares were offered under a previously filed shelf registration statement, and a final prospectus supplement detailing the offering was filed with the SEC on June 3, 2020.
Intellia Therapeutics (NASDAQ: NTLA) has announced a public offering of 5,479,453 shares at $18.25 per share, aiming to raise approximately $100 million. The offering includes a 30-day option for underwriters to buy an additional 821,917 shares. The closing of this offering is anticipated around June 5, 2020, subject to standard closing conditions. Goldman Sachs, Jefferies, and SVB Leerink are the joint book-running managers. Shares are offered under a previously effective shelf registration statement with the SEC.
Intellia Therapeutics (NASDAQ: NTLA) announced a public offering of $75 million in common stock with a 30-day option for underwriters to purchase an additional 15%. The offering is subject to market conditions, and all shares will be sold by Intellia. Goldman Sachs, Jefferies, and SVB Leerink are managing the offer. The shares are available under a shelf registration statement filed with the SEC. This announcement reflects Intellia's ongoing commitment to funding its genome editing technology using CRISPR/Cas9.
Intellia Therapeutics (NASDAQ: NTLA) showcased its innovative CRISPR/Cas9 technology during the ASGCT Annual Meeting, presenting promising data on NTLA-5001 for acute myeloid leukemia (AML) and NTLA-2002 for hereditary angioedema (HAE). The proprietary process for NTLA-5001 enables multiple gene edits in T cells, leading to enhanced therapeutic potential. Data revealed >98% efficiency in gene editing with minimal adverse translocations. NTLA-2002 demonstrated a sustained 90% reduction in kallikrein activity, indicating significant efficacy in reducing HAE attack rates. IND submissions for both drug candidates are anticipated in 2021.
Intellia Therapeutics (NASDAQ: NTLA) announced key updates in its pipeline for Q1 2020, focusing on its CRISPR/Cas9 technology. The company plans to submit INDs for its lead therapies: NTLA-2001 for transthyretin amyloidosis by mid-2020, NTLA-5001 for acute myeloid leukemia in 1H 2021, and NTLA-2002 for hereditary angioedema in 2H 2021. Intellia ended the quarter with a cash position of $250 million, expecting a runway through the end of 2021. However, research and development expenses rose, leading to a net loss of $31.8 million compared to $21.9 million in Q1 2019.
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