Intellia Therape Stock Price, News & Analysis

Intellia Therapeutics (NASDAQ:NTLA) announced the pricing of a public offering of 4,137,931 shares at $145.00 per share, aiming to raise approximately $600 million before expenses. The offering includes a 30-day option for underwriters to purchase up to an additional 620,689 shares. The offering is set to close around July 2, 2021, subject to conditions. Goldman Sachs, Jefferies, SVB Leerink, and Barclays are the joint managers for this offering, which is conducted under an effective SEC shelf registration statement.

Intellia Therapeutics (NASDAQ:NTLA) announced a public offering of $400 million in common stock, with an option for underwriters to purchase an additional 15%. The company aims to utilize proceeds for advancing its CRISPR/Cas9 genome editing technology. Goldman Sachs & Co. LLC, Jefferies, SVB Leerink, and Barclays are joint book-running managers for the offering. The offering is contingent on market conditions and may change. The shares will be sold under an effective registration statement filed with the SEC, ensuring compliance with securities laws.

Intellia Therapeutics and Regeneron Pharmaceuticals announced promising interim results from a Phase 1 trial of NTLA-2001 for treating hereditary transthyretin amyloidosis (ATTRv-PN). The single 0.3 mg/kg dose led to an impressive 87% mean reduction in serum TTR levels, with a maximum reduction of 96% observed by day 28. The treatment showed a favorable safety profile, with no serious adverse events reported among the first six patients. Data was published in The New England Journal of Medicine and presented at the Peripheral Nerve Society Annual Meeting. Future expansions of the trial are planned.

Intellia Therapeutics (NTLA) announced promising interim results from its Phase 1 trial of NTLA-2001, the first in vivo CRISPR genome editing therapy for hereditary transthyretin amyloidosis with polyneuropathy. A 0.3 mg/kg dose led to an 87% mean reduction in serum TTR levels, peaking at 96% by day 28. The treatment exhibited a favorable safety profile with no serious adverse events in the first six patients. These findings, published in The New England Journal of Medicine, highlight NTLA-2001's potential as a single-dose therapy that could transform treatment outcomes for this serious condition.

Intellia Therapeutics (NASDAQ: NTLA) has appointed James Basta as Executive Vice President, General Counsel, and Corporate Secretary. With over 25 years of legal experience, Basta previously served as Chief Legal Officer at Kura Oncology and held significant roles at Biogen. He succeeds José Rivera, a founding employee, who will assist during the transition. Intellia's leadership believes Basta's expertise will bolster their mission to develop curative genome editing therapies. Forward-looking statements address potential risks in advancing their CRISPR/Cas9 technology and pipeline.

Blackstone (NYSE: BX) has announced a $250 million investment to establish a new CAR T-cell therapy company alongside Intellia Therapeutics (NASDAQ: NTLA) and Cellex. This venture will feature a blend of GEMoaB's advanced CAR-T technology and Intellia's CRISPR genomic engineering. Aimed at improving efficacy and safety across various cancers, the new company will be based in Cambridge, Massachusetts, with operations in Germany. Andrew Schiermeier will lead this initiative, focusing on providing innovative treatments for tough-to-treat cancers and autoimmune conditions.

Intellia Therapeutics (NASDAQ:NTLA) announced that interim Phase 1 data from its lead CRISPR therapy, NTLA-2001, will be presented on June 26. This therapy aims to treat transthyretin amyloidosis (ATTR) with a single, systemically administered dose. The ongoing trial targets hereditary ATTR amyloidosis with polyneuropathy. Initial results will assess safety and pharmacodynamics, presenting a potential breakthrough in treatment compared to the traditional lifelong therapies. Following the Phase 1 trial, further studies will evaluate NTLA-2001's effectiveness in a broader ATTR population.

Intellia Therapeutics (NASDAQ:NTLA) reported first-quarter 2021 results, ending March 31 with $600.8 million in cash. The company plans to announce initial safety data for NTLA-2001, a CRISPR-based therapy for transthyretin amyloidosis (ATTR), in mid-2021 and to submit IND applications for NTLA-5001 (acute myeloid leukemia) and NTLA-2002 (hereditary angioedema) in 2021. Research and development expenses increased to $39.3 million due to advancements in key programs. The company recorded a net loss of $46.2 million, up from $31.8 million year-over-year.

Intellia Therapeutics (NASDAQ:NTLA) announced it will present its first quarter 2021 financial results and operational highlights on May 6, 2021, at 8 a.m. ET. The conference call will allow investors to understand the company's progress in developing proprietary therapeutics using CRISPR/Cas9 technology. U.S. callers can dial 1-833-316-0545; international callers should use 1-412-317-5726. A replay will be available on the company's website later that day.