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NeuroSense Therapeutics Ltd. Ordinary Shares - NRSN STOCK NEWS

Welcome to our dedicated page for NeuroSense Therapeutics Ltd. Ordinary Shares news (Ticker: NRSN), a resource for investors and traders seeking the latest updates and insights on NeuroSense Therapeutics Ltd. Ordinary Shares stock.

NeuroSense Therapeutics Ltd. (NASDAQ: NRSN) is a clinical-stage biotechnology company focused on discovering and developing treatments for patients suffering from debilitating neurodegenerative diseases. These diseases encompass Amyotrophic Lateral Sclerosis (ALS), Alzheimer's disease, and Parkinson's disease, among others.

The company's flagship product, PrimeC, is a novel extended-release oral formulation, combining ciprofloxacin and celecoxib in a specific ratio designed for synergistic effect. PrimeC aims to target several key mechanisms of ALS, including motor neuron degeneration, inflammation, iron accumulation, and impaired RNA regulation. The formulation has shown promising results in clinical trials, including a significant slowing of disease progression in Phase 2b studies.

In their recent PARADIGM Phase 2b clinical trial, NeuroSense demonstrated compelling data with a 37% reduction in the progression of ALS, with further subgroup analysis showing even higher efficacy in specific patient populations. This trial's success propelled the company towards preparing for a Phase 3 pivotal trial, with extensive collaboration and validation from industry experts.

NeuroSense has been active in forming strategic partnerships to enhance its research and development capabilities. Notable collaborations include agreements with Lonza for biomarker development, and Genetika+ for Alzheimer's disease drug development. These partnerships leverage cutting-edge technologies to optimize clinical outcomes and advance the company's therapeutic solutions.

Financially, NeuroSense reported an increase in R&D expenses from $6.4 million in 2022 to $7.6 million in 2023, reflecting its investment in expanding its workforce and clinical programs. Conversely, general and administrative expenses saw a decrease, contributing to an efficient allocation of resources. As of December 31, 2023, the company had a cash position of approximately $2.6 million.

With multiple ongoing projects and a robust pipeline, NeuroSense is set to play a significant role in addressing the unmet medical needs in neurodegenerative diseases. The company's dedication to advancing research and developing novel therapies positions it as a key player in biotech innovation.

For more information, visit NeuroSense's investor relations website at https://neurosense.investorroom.com/.

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NeuroSense Therapeutics Ltd. (Nasdaq: NRSN) has regained compliance with the minimum bid price requirement under Nasdaq Listing Rule 5550(a)(2), ensuring continued listing on the Nasdaq Stock Market. The company's CEO, Alon Ben-Noon, expressed the importance of this event as they focus on advancing PrimeC and reporting results from their collaboration with Biogen.
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NRSN Announces Positive Phase 2 Clinical Trial Results for ALS Treatment
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NeuroSense Therapeutics Ltd. (NASDAQ: NRSN) shares a review of important clinical achievements in 2023, including a statistically significant reduction in ALS disease progression in Phase 2b PARADIGM trial. The company anticipates several biomarker study results in 2024 and partnership discussions as it advances its drug development.
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NeuroSense Therapeutics Ltd. (Nasdaq: NRSN) received a notification from Nasdaq regarding non-compliance with minimum stockholders' equity requirement. The company has 45 days to submit a plan to regain compliance, with a potential extension of up to 180 days if the plan is accepted. The notification does not immediately affect the listing or trading of NeuroSense's ordinary shares.
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NeuroSense Therapeutics Ltd. (Nasdaq: NRSN) reported a statistically significant 37.4% slowing of disease progression in ALSFRS-R with PrimeC compared to placebo, as revealed in the Phase 2b trial (PARADIGM) evaluation. The trial also showed a strong safety profile and favorable clinical results, with potential partnerships and regulatory meetings expected in 2024.
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NeuroSense Therapeutics Ltd. (Nasdaq: NRSN) reported positive top-line results from its Phase 2b PARADIGM trial for PrimeC, a drug candidate for ALS. The trial demonstrated a 29% difference in favor of PrimeC in slowing disease progression, with comparable safety and tolerability to placebo. NeuroSense expects to release additional biomarker data in early 2024 and is looking forward to advancing discussions with strategic partners.
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NeuroSense Therapeutics Ltd. (Nasdaq: NRSN) will report new data from the randomized, placebo-controlled, double-blind segment of its ongoing Phase 2b ALS trial of its lead drug candidate PrimeC. The data will include safety, tolerability endpoints, and clinical efficacy outcome measures. The conference call will be held at 8:30 am ET, and the webcast will be available for replay for 30 days.
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NeuroSense Therapeutics Ltd. (Nasdaq: NRSN) reported topline clinical results from its Phase 2b ALS trial, with a cash runway extending into Q2 2024. The company also confirmed the FDA's CMC strategy for PrimeC, demonstrated PrimeC's outstanding effect on ALS survival, and is preparing for a Phase 2 Alzheimer's disease trial.
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NeuroSense Therapeutics Ltd. (NASDAQ: NRSN) announces successful Type D meeting with the FDA for PrimeC in ALS treatment, confirming CMC strategy for Phase 3 trial and commercial launch. Clinical efficacy top-line results of PARADIGM, a Phase 2b trial in ALS, expected in December 2023.
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NeuroSense Therapeutics Ltd. (Nasdaq: NRSN) announces scientific presentations at three upcoming conferences, including the Society of Neuroscience's annual conference and the 34th International Symposium on ALS/MND. The last patient has completed the double-blind segment of PARADIGM, with clinical efficacy results expected in December 2023.
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FAQ

What is the current stock price of NeuroSense Therapeutics Ltd. Ordinary Shares (NRSN)?

The current stock price of NeuroSense Therapeutics Ltd. Ordinary Shares (NRSN) is $1.36 as of December 20, 2024.

What is the market cap of NeuroSense Therapeutics Ltd. Ordinary Shares (NRSN)?

The market cap of NeuroSense Therapeutics Ltd. Ordinary Shares (NRSN) is approximately 28.9M.

What is NeuroSense Therapeutics' main focus?

NeuroSense Therapeutics focuses on discovering and developing treatments for debilitating neurodegenerative diseases such as ALS, Alzheimer's disease, and Parkinson's disease.

What is PrimeC?

PrimeC is NeuroSense's lead drug candidate, a novel extended-release oral formulation combining ciprofloxacin and celecoxib, designed to target key mechanisms of ALS.

What were the results of the PARADIGM Phase 2b trial?

The PARADIGM Phase 2b trial showed that PrimeC significantly slowed the progression of ALS by 37%, with further positive outcomes in various patient subgroups.

Who are NeuroSense's key collaborators?

NeuroSense collaborates with Lonza for biomarker development and Genetika+ for Alzheimer's disease drug development, among other partners.

What are the financial highlights for NeuroSense in 2023?

In 2023, NeuroSense reported R&D expenses of $7.6 million and a cash position of approximately $2.6 million as of December 31, 2023.

What diseases is NeuroSense targeting?

NeuroSense targets neurodegenerative diseases including ALS, Alzheimer's disease, and Parkinson's disease.

What is the status of PrimeC's clinical trials?

PrimeC has completed the Phase 2b PARADIGM trial, showing significant efficacy, and NeuroSense is preparing for a Phase 3 pivotal trial.

How does PrimeC work?

PrimeC targets ALS mechanisms like motor neuron degeneration, inflammation, iron accumulation, and impaired RNA regulation through a combination of ciprofloxacin and celecoxib.

Is PrimeC FDA approved?

PrimeC has not yet received FDA approval but has been granted Orphan Drug Designation by the FDA and the European Medicines Agency.

How can I get more information about NeuroSense?

For more information, visit NeuroSense's investor relations website at https://neurosense.investorroom.com/.

NeuroSense Therapeutics Ltd. Ordinary Shares

Nasdaq:NRSN

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28.91M
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23.91%
1.09%
1.3%
Biotechnology
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