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NeuroSense Therapeutics Ltd. Ordinary Shares - NRSN STOCK NEWS

Welcome to our dedicated page for NeuroSense Therapeutics Ltd. Ordinary Shares news (Ticker: NRSN), a resource for investors and traders seeking the latest updates and insights on NeuroSense Therapeutics Ltd. Ordinary Shares stock.

NeuroSense Therapeutics Ltd. (NASDAQ: NRSN) is a clinical-stage biotechnology company focused on discovering and developing treatments for patients suffering from debilitating neurodegenerative diseases. These diseases encompass Amyotrophic Lateral Sclerosis (ALS), Alzheimer's disease, and Parkinson's disease, among others.

The company's flagship product, PrimeC, is a novel extended-release oral formulation, combining ciprofloxacin and celecoxib in a specific ratio designed for synergistic effect. PrimeC aims to target several key mechanisms of ALS, including motor neuron degeneration, inflammation, iron accumulation, and impaired RNA regulation. The formulation has shown promising results in clinical trials, including a significant slowing of disease progression in Phase 2b studies.

In their recent PARADIGM Phase 2b clinical trial, NeuroSense demonstrated compelling data with a 37% reduction in the progression of ALS, with further subgroup analysis showing even higher efficacy in specific patient populations. This trial's success propelled the company towards preparing for a Phase 3 pivotal trial, with extensive collaboration and validation from industry experts.

NeuroSense has been active in forming strategic partnerships to enhance its research and development capabilities. Notable collaborations include agreements with Lonza for biomarker development, and Genetika+ for Alzheimer's disease drug development. These partnerships leverage cutting-edge technologies to optimize clinical outcomes and advance the company's therapeutic solutions.

Financially, NeuroSense reported an increase in R&D expenses from $6.4 million in 2022 to $7.6 million in 2023, reflecting its investment in expanding its workforce and clinical programs. Conversely, general and administrative expenses saw a decrease, contributing to an efficient allocation of resources. As of December 31, 2023, the company had a cash position of approximately $2.6 million.

With multiple ongoing projects and a robust pipeline, NeuroSense is set to play a significant role in addressing the unmet medical needs in neurodegenerative diseases. The company's dedication to advancing research and developing novel therapies positions it as a key player in biotech innovation.

For more information, visit NeuroSense's investor relations website at https://neurosense.investorroom.com/.

Rhea-AI Summary
NeuroSense Therapeutics has completed dosing of the last patient in the double-blind segment of its Phase 2b ALS trial of PrimeC. The company expects to release clinical efficacy results and safety results in December 2023. They also plan to report on the assessment of ALS-biomarkers in H1 2024 and collaborate with Biogen for biomarker analysis. PrimeC has shown promising results in previous trials and has been granted Orphan Drug Designation.
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NeuroSense Therapeutics Ltd. announced that its Chief Medical Officer, Dr. Ferenc Tracik, will participate in the 29th annual BIO-Europe Fall partnering conference in Munich, Germany. The company's lead drug, PrimeC, is in a global Phase 2b study for ALS, with other programs targeting Alzheimer's and Parkinson's diseases.
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NeuroSense Therapeutics' lead drug candidate, PrimeC, has been confirmed to be effective in treating ALS by a renowned ALS researcher.
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NeuroSense Therapeutics provides an update on clinical and operational developments
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NeuroSense's PrimeC shows significant increase in survival rate of induced motor neurons in ALS study, reinforcing previous findings. PrimeC performed among the best in improving motor neuron survival compared to other ALS drugs. Clinical topline results from Phase 2b study expected in Q4 2023.
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NeuroSense terminates equity offering program, fully funded into Q2 2024; ALS Phase 2b trial data expected Q4 2023
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NeuroSense opens EU office and receives SME status from EMA, offering regulatory guidance and engagement. Plans to enroll patients in Phase 3 ALS study. Clinical results from Phase 2b study expected end of 2023. Commences global Phase 3 study in 2024 with numerous European sites. Financial benefits include fee reductions and exemptions.
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NeuroSense receives key patent for ALS treatment drug combination
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NeuroSense to present PARADIGM Phase 2b ALS study at conferences, expects to report topline results in Q4 2023
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NeuroSense Therapeutics will host an investor webinar conference on September 12, 2023, to discuss its scientific advances, clinical trials, and upcoming catalysts. The company is in a strong financial position with a capital runway beyond the expected data readout in Q4 2023.
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FAQ

What is the current stock price of NeuroSense Therapeutics Ltd. Ordinary Shares (NRSN)?

The current stock price of NeuroSense Therapeutics Ltd. Ordinary Shares (NRSN) is $1.36 as of December 20, 2024.

What is the market cap of NeuroSense Therapeutics Ltd. Ordinary Shares (NRSN)?

The market cap of NeuroSense Therapeutics Ltd. Ordinary Shares (NRSN) is approximately 28.9M.

What is NeuroSense Therapeutics' main focus?

NeuroSense Therapeutics focuses on discovering and developing treatments for debilitating neurodegenerative diseases such as ALS, Alzheimer's disease, and Parkinson's disease.

What is PrimeC?

PrimeC is NeuroSense's lead drug candidate, a novel extended-release oral formulation combining ciprofloxacin and celecoxib, designed to target key mechanisms of ALS.

What were the results of the PARADIGM Phase 2b trial?

The PARADIGM Phase 2b trial showed that PrimeC significantly slowed the progression of ALS by 37%, with further positive outcomes in various patient subgroups.

Who are NeuroSense's key collaborators?

NeuroSense collaborates with Lonza for biomarker development and Genetika+ for Alzheimer's disease drug development, among other partners.

What are the financial highlights for NeuroSense in 2023?

In 2023, NeuroSense reported R&D expenses of $7.6 million and a cash position of approximately $2.6 million as of December 31, 2023.

What diseases is NeuroSense targeting?

NeuroSense targets neurodegenerative diseases including ALS, Alzheimer's disease, and Parkinson's disease.

What is the status of PrimeC's clinical trials?

PrimeC has completed the Phase 2b PARADIGM trial, showing significant efficacy, and NeuroSense is preparing for a Phase 3 pivotal trial.

How does PrimeC work?

PrimeC targets ALS mechanisms like motor neuron degeneration, inflammation, iron accumulation, and impaired RNA regulation through a combination of ciprofloxacin and celecoxib.

Is PrimeC FDA approved?

PrimeC has not yet received FDA approval but has been granted Orphan Drug Designation by the FDA and the European Medicines Agency.

How can I get more information about NeuroSense?

For more information, visit NeuroSense's investor relations website at https://neurosense.investorroom.com/.

NeuroSense Therapeutics Ltd. Ordinary Shares

Nasdaq:NRSN

NRSN Rankings

NRSN Stock Data

28.91M
15.87M
23.91%
1.09%
1.3%
Biotechnology
Healthcare
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United States of America
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