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Korro Bio (Nasdaq: KRRO) will participate in several significant investor and scientific conferences in June 2024.
CEO Ram Aiyar, Ph.D., and CFO Vineet Agarwal will present at the Jefferies Global Healthcare Conference on June 6 at 2:00 p.m. ET.
CMO Dr. Kemi Olugemo will discuss Korro's lead RNA editing oligonucleotide candidate, KRRO-110, for treating Alpha-1 Antitrypsin Deficiency at the 2024 Alpha-1 Foundation National Conference on June 8 at 11:20 a.m. ET.
Senior VP Venkat Krishnamurthy, Ph.D., will participate in the 5th Annual RNA Editing Summit on June 20, engaging in a roundtable discussion and giving a presentation on the OPERA platform and its clinical progress.
The Jefferies presentation will be webcast live, with a replay available for 30 days on Korro's website.
Korro Bio presented new preclinical data on KRRO-110 at the 2024 American Thoracic Society International Conference. The data demonstrated sustained editing efficiency of approximately 60% and increased total alpha-1 antitrypsin (AAT) protein levels to over 60µM at week 13 in an in vivo genetic Alpha-1 Antitrypsin Deficiency (AATD) mouse model. Notably, KRRO-110 showed 35µM of M-AAT one week post the first dose, rising to 45µM of M-AAT by week 13. This data suggests KRRO-110's potential as a best-in-class therapeutic for AATD. Korro plans to submit a regulatory filing for a first-in-human study in the second half of 2024.
Korro Bio (Nasdaq: KRRO) reported its financial results for Q1 2024 and announced the appointment of Dr. Kemi Olugemo as Chief Medical Officer. Significant milestones include a $70 million private placement completed in April 2024, increasing cash reserves to $206 million. This funding extends Korro's cash runway into the second half of 2026. Pipeline progress includes plans for a regulatory filing for KRRO-110, targeting Alpha-1 Antitrypsin Deficiency (AATD), in the latter half of 2024. Interim readout for KRRO-110 is expected in H2 2025, with trial completion in 2026. Financial highlights show a decrease in cash from $166.1 million to $138.8 million and a net loss of $19.6 million for Q1 2024, unchanged from the previous year. R&D expenses dropped to $13.6 million, while G&A expenses rose to $7.9 million.