STOCK TITAN

Korro Bio, Inc. - KRRO STOCK NEWS

Welcome to our dedicated page for Korro Bio news (Ticker: KRRO), a resource for investors and traders seeking the latest updates and insights on Korro Bio stock.

Korro Bio, Inc. (NASDAQ: KRRO) is a pioneering biopharmaceutical company based in Cambridge, Massachusetts. The company is dedicated to transforming the landscape of genetic medicine by focusing on RNA editing to treat both rare and common diseases. Unlike traditional genetic engineering, Korro Bio’s innovative approach aims to make precise, transient edits at the RNA level, thereby enhancing precision and adjustability.

Korro Bio is building a diversified portfolio of programs designed to leverage the body's natural RNA editing mechanisms. Its lead program, KRRO-110, is under development for the treatment of Alpha-1 Antitrypsin Deficiency (AATD), a genetic disorder affecting the lungs and liver. Recently presented preclinical data for KRRO-110 demonstrated approximately 60% editing efficiency and significant protein restoration, showing promise as a potential best-in-class treatment for AATD. The company plans to file for regulatory approval for a first-in-human study in the second half of 2024.

With an emphasis on leveraging established delivery methods and regulatory pathways, Korro Bio is well-positioned to bring its RNA-editing therapies to market swiftly. The company also collaborates with various stakeholders to enhance its research and development capabilities, ensuring robust and efficient pipeline progression. For more information, visit korrobio.com.

Rhea-AI Summary

Korro Bio (NASDAQ: KRRO) reported Q2 2024 financial results and provided business updates. Key highlights include:

1. Regulatory filing for KRRO-110 in alpha-1 antitrypsin deficiency (AATD) expected in H2 2024.

2. Preclinical data presented at ATS 2024 showed KRRO-110's ability to correct AAT protein, resulting in >70% M-AAT in circulation.

3. Q2 2024 ended with $187.8 million in cash, cash equivalents, and marketable securities.

4. Cash runway extended into H2 2026, funding KRRO-110 FIH trial completion and pipeline advancement.

5. Q2 2024 financial results: R&D expenses $17.1 million, G&A expenses $7.0 million, net loss $21.8 million.

6. Interim Phase 1/2 clinical trial readout for KRRO-110 in ZZ AATD patients expected in H2 2025.

Rhea-AI Impact
Rhea-AI Sentiment
End-of-Day
-- %
Tags
-
Rhea-AI Summary

Korro Bio has been added to the Russell 2000, Russell 3000, and Russell Microcap Indexes as part of the annual reconstitution effective July 1, 2024. This inclusion is based on market capitalization rankings determined by FTSE Russell. Korro Bio's CEO, Dr. Ram Aiyar, emphasized their commitment to advancing their drug candidate, KRRO-110, for Alpha-1 Antitrypsin Deficiency, with plans to file with regulatory agencies in the second half of 2024 and an interim data readout in the second half of 2025. The inclusion in these indexes is expected to enhance value for Korro's stakeholders.

Rhea-AI Impact
Rhea-AI Sentiment
End-of-Day
-0.06%
Tags
none
-
Rhea-AI Summary

Korro Bio (Nasdaq: KRRO) will participate in several significant investor and scientific conferences in June 2024.

CEO Ram Aiyar, Ph.D., and CFO Vineet Agarwal will present at the Jefferies Global Healthcare Conference on June 6 at 2:00 p.m. ET.

CMO Dr. Kemi Olugemo will discuss Korro's lead RNA editing oligonucleotide candidate, KRRO-110, for treating Alpha-1 Antitrypsin Deficiency at the 2024 Alpha-1 Foundation National Conference on June 8 at 11:20 a.m. ET.

Senior VP Venkat Krishnamurthy, Ph.D., will participate in the 5th Annual RNA Editing Summit on June 20, engaging in a roundtable discussion and giving a presentation on the OPERA platform and its clinical progress.

The Jefferies presentation will be webcast live, with a replay available for 30 days on Korro's website.

Rhea-AI Impact
Rhea-AI Sentiment
End-of-Day
2.09%
Tags
conferences
Rhea-AI Summary

Korro Bio presented new preclinical data on KRRO-110 at the 2024 American Thoracic Society International Conference. The data demonstrated sustained editing efficiency of approximately 60% and increased total alpha-1 antitrypsin (AAT) protein levels to over 60µM at week 13 in an in vivo genetic Alpha-1 Antitrypsin Deficiency (AATD) mouse model. Notably, KRRO-110 showed 35µM of M-AAT one week post the first dose, rising to 45µM of M-AAT by week 13. This data suggests KRRO-110's potential as a best-in-class therapeutic for AATD. Korro plans to submit a regulatory filing for a first-in-human study in the second half of 2024.

Rhea-AI Impact
Rhea-AI Sentiment
End-of-Day
-0.11%
Tags
-
Rhea-AI Summary

Korro Bio (Nasdaq: KRRO) reported its financial results for Q1 2024 and announced the appointment of Dr. Kemi Olugemo as Chief Medical Officer. Significant milestones include a $70 million private placement completed in April 2024, increasing cash reserves to $206 million. This funding extends Korro's cash runway into the second half of 2026. Pipeline progress includes plans for a regulatory filing for KRRO-110, targeting Alpha-1 Antitrypsin Deficiency (AATD), in the latter half of 2024. Interim readout for KRRO-110 is expected in H2 2025, with trial completion in 2026. Financial highlights show a decrease in cash from $166.1 million to $138.8 million and a net loss of $19.6 million for Q1 2024, unchanged from the previous year. R&D expenses dropped to $13.6 million, while G&A expenses rose to $7.9 million.

Rhea-AI Impact
Rhea-AI Sentiment
End-of-Day
5.43%
Tags
management earnings
-
Rhea-AI Summary
Korro Bio, Inc. announces a $70 million private placement led by Deep Track Capital and other healthcare investors. The financing is expected to close on April 22, 2024, providing pro-forma cash of approximately $236 million. Korro plans to use the proceeds for regulatory filings, interim readouts, and study completions for its genetic medicines. The company aims to advance its pipeline programs and platform development, with a focus on delivery and machine learning.
Rhea-AI Impact
Rhea-AI Sentiment
End-of-Day
-3.64%
Tags
none
Rhea-AI Summary
Korro Bio, Inc. announces CEO and executives' participation in upcoming investor conferences to discuss progress on KRRO-110, a promising candidate for AATD treatment.
Rhea-AI Impact
Rhea-AI Sentiment
End-of-Day
-7.9%
Tags
conferences
-
Rhea-AI Summary
Korro Bio, Inc. (KRRO) reports strong financials for 2023, with a cash balance of $166 million, anticipating regulatory filing for KRRO-110 in AATD patients in late 2024. The company demonstrated over 50% editing using GalNAc conjugates in a preclinical mouse model and achieved significant milestones in pipeline development.
Rhea-AI Impact
Rhea-AI Sentiment
End-of-Day
1.82%
Tags
-
Rhea-AI Summary
Korro Bio, Inc. (KRRO) announced CEO Ram Aiyar will present at TD Cowen 44th Annual Health Care Conference. CFO and CSO to participate. Webcast available on Korro's website.
Rhea-AI Impact
Rhea-AI Sentiment
End-of-Day
-6.08%
Tags
conferences
Rhea-AI Summary
Korro Bio, Inc. presented new data for KRRO-110 at the J.P. Morgan Healthcare Conference, showcasing its potential as a best-in-class therapeutic for AATD patients. The company reported progress across its RNA editing portfolio, demonstrating high specificity and sustained protein correction in preclinical mouse models. Korro's proprietary RNA editing platform, OPERA™, has shown potential in creating de novo mutations to alter protein function, with promising results in activating transcription factors and modulating ion channels.
Rhea-AI Impact
Rhea-AI Sentiment
End-of-Day
-5.98%
Tags
none

FAQ

What is the current stock price of Korro Bio (KRRO)?

The current stock price of Korro Bio (KRRO) is $43.67 as of December 20, 2024.

What is the market cap of Korro Bio (KRRO)?

The market cap of Korro Bio (KRRO) is approximately 410.8M.

What is Korro Bio, Inc.?

Korro Bio is a biopharmaceutical company focusing on RNA editing to treat both rare and common diseases.

What is RNA editing?

RNA editing is a process that makes precise, transient changes to RNA, providing an alternative to DNA-based genetic engineering.

What is KRRO-110?

KRRO-110 is Korro Bio’s lead program aimed at treating Alpha-1 Antitrypsin Deficiency (AATD).

What recent achievements has Korro Bio made?

Korro Bio recently presented preclinical data showing significant efficacy for KRRO-110 in protein restoration for AATD treatment.

When does Korro Bio plan to start human trials for KRRO-110?

Korro Bio expects to submit a regulatory filing for a first-in-human study of KRRO-110 in the second half of 2024.

Where is Korro Bio located?

Korro Bio is based in Cambridge, Massachusetts.

What diseases does Korro Bio target?

Korro Bio targets both rare and highly prevalent diseases using RNA editing technologies.

How does Korro Bio’s approach differ from traditional genetic engineering?

Korro Bio focuses on editing RNA instead of DNA, offering more precision and tunability.

What partnerships does Korro Bio have?

Korro Bio collaborates with stakeholders to advance its research and development capabilities, though specific partners are not detailed.

How can I stay updated on Korro Bio’s latest news?

Visit Korro Bio’s website at korrobio.com for the latest updates and news.

Korro Bio, Inc.

Nasdaq:KRRO

KRRO Rankings

KRRO Stock Data

410.85M
8.77M
6.44%
91.38%
2.61%
Biotechnology
Pharmaceutical Preparations
Link
United States of America
CAMBRIDGE