Geron Corp - GERN STOCK NEWS

Geron Corporation (Nasdaq: GERN) announced new clinical data for imetelstat, a first-in-class telomerase inhibitor, presented at EHA2021 Virtual Congress. The data support imetelstat's mechanism targeting malignant stem and progenitor cells, emphasizing its potential to transform treatment for myelodysplastic syndromes (MDS) and myelofibrosis (MF). Results from the IMerge Phase 2 trial indicate durable transfusion independence, while safety analyses show manageable adverse events. Geron is conducting two Phase 3 trials for imetelstat, which has received Fast Track designation from the FDA.

Geron Corporation (Nasdaq: GERN) announced two poster presentations at the EHA Annual Congress regarding clinical data for imetelstat, a telomerase inhibitor. The posters, available on June 11, 2021, showcase findings from the Phase 2 IMbark and IMerge trials, highlighting imetelstat's efficacy in treating lower risk MDS and MF patients. Notably, it demonstrated clinical benefit across molecular subtypes and an acceptable safety profile. Geron is advancing imetelstat for regulatory approval, having received Fast Track designation from the FDA.

Geron Corporation (Nasdaq: GERN) reported financial results for Q1 2021, posting a net loss of $27.8 million, or $0.09 per share, compared to a loss of $16.4 million, or $0.08 per share, in Q1 2020. Revenues increased to $137,000 from $52,000 year-over-year. The company maintains $244.7 million in cash, expected to fund operations until 2022. Geron is progressing in two Phase 3 clinical trials for imetelstat, with 75% enrollment in MDS and the first patient dosed in MF. The company aims for a commercial launch of imetelstat in 2023, with ongoing preparations for regulatory filings.

Geron Corporation (Nasdaq: GERN) will release its first quarter 2021 financial results on May 10, 2021, after market close. A conference call will follow at 4:30 p.m. ET to discuss results and recent developments. Investors can access the press release and the live webcast on the company's website. Geron is advancing a first-in-class telomerase inhibitor, imetelstat, targeting hematologic malignancies and is currently conducting two Phase 3 trials: IMerge and IMpactMF. For further information, visit www.geron.com.

Geron Corporation (Nasdaq: GERN) announced the granting of non-statutory stock options for 220,000 shares to new employees as employment inducements. These options were issued on April 21, 2021, with an exercise price of $1.48, matching the closing stock price on the grant date. The options have a 10-year term and vest over four years, with an initial 12.5% vesting at the six-month mark. This action complies with Nasdaq Listing Rule 5635(c)(4). Geron is currently focused on developing its telomerase inhibitor, imetelstat, through two Phase 3 clinical trials.

Geron Corporation (Nasdaq: GERN) has initiated dosing for the first patient in its Phase 3 clinical trial, IMpactMF, studying imetelstat for refractory myelofibrosis (MF), with overall survival as the primary endpoint. This trial, targeting 320 patients, addresses a significant unmet need given the median overall survival of 14-16 months for those unresponsive to JAK inhibitors. Interim results are anticipated in 2024, with final results expected in 2025. Imetelstat is also Fast Track designated by the FDA for certain patient populations, enhancing its development prospects.

Geron Corporation (Nasdaq: GERN) announced the issuance of non-statutory stock options for 240,000 shares to newly hired employees. These options were granted on March 17, 2021, at an exercise price of $1.81 per share, matching the stock's closing price on that date. The options have a 10-year term and vest over four years, with 12.5% vesting after six months of employment. This grant complies with Nasdaq Listing Rule 5635(c)(4) and is part of Geron's 2018 Inducement Award Plan aimed at attracting new talent.

Geron Corporation (Nasdaq: GERN) reported its financial results for Q4 and FY 2020, ending with $260 million in cash and marketable securities, expected to last until late 2022. The company is advancing its Phase 3 trials for imetelstat in hematologic malignancies, with IMerge Phase 3 expected to be fully enrolled in H2 2021. However, COVID-19 has caused delays in enrollment. Fiscal 2020 net loss was $75.6 million, with revenues of $253,000. Geron anticipates operating expenses between $108 and $112 million in 2021 while preparing for a potential NDA submission in 2023.

Geron Corporation (Nasdaq: GERN) will announce its fourth quarter and full year 2020 financial results on March 11, 2021, after market close. A conference call will follow at 4:30 p.m. ET to discuss these results and recent developments. Interested participants can access the call via a pre-registration link. Geron focuses on developing imetelstat, a telomerase inhibitor, currently being tested in two Phase 3 trials: IMerge for lower-risk myelodysplastic syndromes and IMpactMF for refractory myelofibrosis. More details are available on their website.