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Geron Corp - GERN STOCK NEWS

Welcome to our dedicated page for Geron news (Ticker: GERN), a resource for investors and traders seeking the latest updates and insights on Geron stock.

Overview

Geron Corp (GERN) is a clinical-stage biopharmaceutical company committed to pioneering innovative therapies in the field of oncology. At the heart of its research is the development of first-in-class telomerase inhibitors, which target the underlying cellular mechanism that enables cancer cells to maintain telomere length—a key factor that contributes to their unchecked replication. This advanced approach positions Geron as a focused innovator within the broad landscape of cancer treatment development, emphasizing a precision-driven strategy that seeks to fundamentally alter how hematologic cancers are managed.

Core Business and Therapeutic Focus

The company’s main product candidate, imetelstat, is a potent, specific inhibitor designed to disrupt telomerase activity. This mechanism is central to the survival and proliferation of cancer cells, particularly in hematologic malignancies. By inhibiting telomerase, imetelstat potentially restricts the limitless division of malignant cells, thereby offering a novel therapeutic pathway for conditions such as myelodysplastic syndromes and myelofibrosis. The clinical-stage exploration of imetelstat underscores Geron Corp's commitment to transforming cancer treatment protocols and deepening our understanding of oncology therapy.

Revenue Model and Corporate Strategy

Geron Corp operates with a revenue model rooted in strategic collaborations within the pharmaceutical and biotechnology sectors. The company leverages licensing agreements, milestone-based payments, and royalty structures to support its research and operational endeavors. This multifaceted approach not only diversifies the financial underpinnings of its business strategy but also reinforces its role as an essential contributor to the oncology therapeutic landscape.

Industry Position and Research Emphasis

Within the competitive framework of biopharmaceutical research, Geron distinguishes itself by focusing exclusively on the development of innovative cancer therapies. Its research-driven approach is underscored by rigorous clinical studies and a deep understanding of the molecular biology of cancer. The company is positioned among specialized entities that are exploring targeted treatment options, relying on sophisticated scientific methodologies to bridge the gap between research innovations and practical, clinical applications.

Scientific and Clinical Expertise

Geron Corp marries scientific inquiry with clinical application through its emphasis on personalized and mechanism-based approaches in treating cancer. Its efforts in developing imetelstat represent a blend of cutting-edge research and meticulous clinical evaluation, providing insights into the potential of telomerase inhibition as a therapeutic modality. By prioritizing expert analysis over speculative claims, Geron consistently communicates an evidence-based narrative that underpins its clinical trials and strategic partnerships.

Operational and Strategic Highlights

  • Innovative Mechanism of Action: The focus on telomerase inhibition addresses a fundamental aspect of cancer cell immortality, offering a concrete rationale behind the therapeutic potential of imetelstat.
  • Focused Clinical Applications: With a targeted approach to hematologic malignancies, Geron becomes a key player in the niche area of blood cancer therapies.
  • Strategic Collaborations: Revenue generation through partnerships and licensing highlights the company’s integrated approach to research, development, and commercial strategy.
  • Scientific Rigor: The company’s operations are underpinned by robust clinical research, embodying the principles of precise and evidence-based innovation in oncology.

Conclusion

In summary, Geron Corp represents a paradigm of focused research and development within the biopharmaceutical industry. Its innovative approach to cancer treatment, primarily through the development of a first-in-class telomerase inhibitor, underscores its commitment to addressing complex oncological challenges through scientific precision and clinical expertise. This detailed exploration helps investors, analysts, and industry watchers gain a nuanced understanding of Geron Corp’s operations, setting a clear context for its role in the evolving landscape of cancer therapeutics.

Rhea-AI Summary

Geron Corporation (Nasdaq: GERN) announced the grant of non-statutory stock options for 320,000 shares of common stock to new employees as inducements for their commencement of employment. The options, set at an exercise price of $1.03 per share, have a 10-year term and will vest over four years. This grant adheres to Nasdaq Listing Rule 5635(c)(4) and is part of Geron's 2018 Inducement Award Plan. The company is currently engaged in two Phase 3 clinical trials for its telomerase inhibitor, imetelstat, targeting hematologic malignancies.

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Geron Corporation (Nasdaq: GERN) announced key business updates and financial results for Q4 and FY 2021. The company reported a net loss of $32 million for Q4 2021 and $116.1 million for the year, with revenues of $1 million for Q4 and $1.4 million for the year. Geron ended 2021 with $212.7 million in cash, supporting operations through Q1 2023. Upcoming milestones include top-line results from the IMerge Phase 3 trial in early January 2023 and plans to submit a New Drug Application for imetelstat in the US in 2023. The company anticipates expanding its clinical programs in 2022.

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Geron Corporation (NASDAQ: GERN) will release its fourth quarter and full year 2021 financial results after market close on March 10, 2022. A conference call will be held at 4:30 p.m. ET on the same day to discuss the results and upcoming milestones. Investors can access the press release on the company’s website. Geron is focused on developing imetelstat, a telomerase inhibitor, for hematologic malignancies, with ongoing Phase 3 clinical trials for lower risk myelodysplastic syndromes and refractory myelofibrosis.

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Geron Corporation (NASDAQ: GERN) announced that its Chairman and CEO, John A. Scarlett, will participate in a fireside chat at the B. Riley Securities Virtual Oncology Investor Conference on January 28, 2022, at 11:00 a.m. ET. A live webcast of the presentation will be available on Geron's Investor Relations website and archived for 30 days after the event. Geron focuses on developing imetelstat, a first-in-class telomerase inhibitor, for treating hematologic malignancies, currently conducting two Phase 3 clinical trials: IMerge and IMpactMF.

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Geron Corporation (NASDAQ: GERN) announced the grant of non-statutory stock options totaling 435,800 shares to new employees as an inducement for employment. These options were issued on January 19, 2022, with an exercise price of $1.10 per share, aligning with the stock's closing price. The options have a 10-year term and vest over four years, starting with 12.5% after six months and the remainder in equal installments. This action is in compliance with Nasdaq regulations and is part of Geron's 2018 Inducement Award Plan.

Geron is focusing on developing imetelstat, a telomerase inhibitor, for hematologic malignancies.

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Geron Corporation (Nasdaq: GERN), a biopharmaceutical company, announced that CEO John A. Scarlett will present at the H.C. Wainwright BioConnect Conference. The pre-recorded presentation will be accessible starting at 7 a.m. ET on January 10, 2022, via a provided link and will be archived for 30 days post-event. Geron focuses on a first-in-class telomerase inhibitor, imetelstat, currently in two Phase 3 clinical trials: IMerge for lower risk myelodysplastic syndromes and IMpactMF for refractory myelofibrosis.

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Geron Corporation (Nasdaq: GERN) announced the grant of a non-statutory stock option for 50,000 shares of common stock to a newly hired employee, effective December 15, 2021. The option has an exercise price of $1.37 per share, matching the stock's closing price on that date. It carries a 10-year term and vests over four years, with 12.5% vesting after six months and the remainder in equal installments over the next 42 months, subject to continued employment. This grant adheres to Nasdaq Listing Rule 5635(c)(4) and is part of Geron's 2018 Inducement Award Plan.

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Geron Corporation (GERN) announced three poster presentations at the 63rd American Society of Hematology Annual Meeting regarding imetelstat, its novel telomerase inhibitor. The posters showcase ongoing Phase 3 trials for imetelstat in lower risk myelodysplastic syndromes (MDS) and refractory myelofibrosis (MF), emphasizing its potential clinical benefits and safety. Results from the IMerge Phase 3 trial are expected in early January 2023, while the IMpactMF trial continues patient enrollment. Imetelstat has received Fast Track designation from the FDA for specific hematological conditions.

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Geron Corporation (NASDAQ: GERN) announces the appointment of Edward Koval as Executive Vice President and Chief Business Officer, enhancing its executive team. Koval brings over 25 years of biotech experience and will focus on business development related to Geron's imetelstat and telomerase inhibitor franchises. Top-line results from the IMerge Phase 3 trial are expected in 13 months, while an interim analysis of the IMpactMF trial is anticipated in 2024. This leadership shift aims to maximize the potential of Geron's innovative treatments in hematologic malignancies.

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Geron Corporation (Nasdaq: GERN) announced the granting of a non-statutory stock option for 80,000 shares as an inducement for a new employee starting on November 17, 2021. The exercise price is $1.42 per share, matching the stock's closing price on the grant date. The option has a 10-year term, with a vesting schedule over four years, starting with 12.5% after six months, then monthly installments. This grant complies with Nasdaq Listing Rule 5635(c)(4) and is part of Geron's 2018 Inducement Award Plan.

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FAQ

What is the current stock price of Geron (GERN)?

The current stock price of Geron (GERN) is $1.48 as of April 1, 2025.

What is the market cap of Geron (GERN)?

The market cap of Geron (GERN) is approximately 938.7M.

What is Geron Corp's primary focus?

Geron Corp is dedicated to the research and development of innovative cancer therapies, particularly through the use of first-in-class telomerase inhibitors.

How does the company plan to treat cancers?

The company is exploring the use of imetelstat, a potent telomerase inhibitor, to target the cell replication process in hematologic malignancies such as myelodysplastic syndromes and myelofibrosis.

What makes Geron Corp's approach unique?

Geron Corp employs a targeted mechanism-based strategy by inhibiting telomerase, a key enzyme that allows cancer cells limitless replication, thus addressing a fundamental aspect of cancer biology.

How does Geron generate revenue?

The company generates revenue primarily through collaboration agreements, licensing arrangements, milestone payments, and royalties, which support its research and clinical operations.

How is Geron positioned within the oncology research space?

Geron Corp is recognized for its focused research on telomerase inhibition, situating it among specialized entities within the broader oncology and biopharmaceutical sectors.

What therapeutic areas are targeted by imetelstat?

Imetelstat is primarily being developed for hematologic malignancies, with a focus on diseases such as myelodysplastic syndromes and myelofibrosis, where traditional treatment options are limited.
Geron Corp

Nasdaq:GERN

GERN Rankings

GERN Stock Data

938.67M
632.76M
0.1%
78.42%
9.17%
Biotechnology
Pharmaceutical Preparations
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United States
FOSTER CITY