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Fate Therapeutics, Inc. (NASDAQ: FATE) is a clinical-stage biopharmaceutical company based in the United States, specializing in the development of programmed cellular immunotherapies for cancer and autoimmune disorders. The company's innovative approach leverages induced pluripotent stem cell (iPSC) technology to create off-the-shelf, engineered NK- and T-cell product candidates designed to deliver multiple therapeutic mechanisms to patients.
Fate Therapeutics' proprietary iPSC product platform enables the mass production of multiplexed-engineered cell products that are uniform in composition and can be stored for off-the-shelf availability. This platform allows for the efficient manufacture of well-defined cell therapies that can be used in combination with other treatments, significantly overcoming the limitations of patient- or donor-sourced cells.
Recent highlights include the initiation of patient enrollment in the Phase 1 study of FT522, an ADR-armed, CD19-targeted CAR NK cell program for B-cell lymphoma. Additionally, the FDA has cleared the IND application for FT825/ONO-8250 in solid tumors, marking a key milestone in the company's collaboration with ONO Pharmaceutical. The expansion of the iPSC product platform into autoimmunity with FT819, targeting systemic lupus erythematosus, further underscores Fate Therapeutics' commitment to addressing complex diseases.
The company's financial health remains robust, bolstered by recent funding efforts, including the sale of shares and pre-funded warrants to institutional investors. Fate Therapeutics continues to lead in the field of cellular immunotherapies, with a strong pipeline of product candidates and an intellectual property portfolio comprising over 500 issued patents and 500 pending patent applications.
Headquartered in San Diego, CA, Fate Therapeutics is dedicated to advancing its clinical programs and providing innovative treatments to improve patient outcomes. For more information, please visit www.fatetherapeutics.com.
Fate Therapeutics (NASDAQ: FATE) announced the acceptance of four oral presentations at the 62nd American Society of Hematology Annual Meeting, to be held virtually from December 5-8, 2020. These presentations will focus on the company’s iPSC-derived NK cell therapies, particularly FT596, in clinical trials for B-cell lymphoma. Additionally, an investor event titled "The Power of hnCD16" is scheduled for December 4, showcasing the functionality of the hnCD16 Fc receptor, which enhances tumor-targeting capabilities. The company aims to develop scalable, off-the-shelf cancer immunotherapies.
Fate Therapeutics, Inc. (NASDAQ: FATE) will host a conference call on November 5, 2020, at 5:00 p.m. ET to discuss its third quarter 2020 financial results and provide a corporate update.
Participants can join by calling (877) 303-6235 domestically or (631) 291-4837 internationally using conference ID 1060606.
The live audio webcast will be accessible via the company's website, with an archived version available two hours post-event.
Fate Therapeutics (NASDAQ: FATE) announced that five abstracts for its iPSC product platform will be presented at the upcoming SITC annual meeting from November 9-14, 2020. The abstracts highlight clinical data from 15 patients in the Phase 1 trial of FT500 for advanced solid tumors. This includes a dose-expansion stage for patients with non-small cell lung cancer or Hodgkin lymphoma. The presentation topics include targeting tumor antigens and the efficacy of iPSC-derived NK cell immunotherapy. Fate's iPSC platform aims to create effective, off-the-shelf therapies, supported by a robust patent portfolio.
Fate Therapeutics (NASDAQ: FATE) announced its participation in the Jefferies Cell Therapy Virtual Summit on October 6, 2020, at 2:30 p.m. E.T.. The management will engage in a fireside chat to discuss advancements in their programmed cellular immunotherapies for cancer and immune disorders. A live webcast of the presentation will be accessible via the company's investor relations webpage. Fate Therapeutics is known for its innovative iPSC product platform, developing both cancer immunotherapies and treatments for immune disorders.
Fate Therapeutics (NASDAQ: FATE) announced its participation in several investor conferences scheduled for September 2020, including the Baird Global Healthcare Conference and the Citi 15th Annual BioPharma Conference. The company, known for its innovative cellular immunotherapies for cancer and immune disorders, is set to present at multiple venues over the course of the month. Interested investors can access live webcasts on the company’s investor relations website, with archived replays available shortly thereafter.
Fate Therapeutics reported encouraging early clinical data for its FT596 product in a patient with refractory diffuse large B-cell lymphoma, showing a partial response with significant tumor size reduction and no serious side effects. The company has cleared multiple IND applications for its innovative iPSC-derived therapies, including FT538 for AML and FT819 for B-cell leukemias, and continues to advance its collaboration with Janssen to develop CAR NK and CAR T-cell therapies. As of June 30, 2020, Fate Therapeutics had $533 million in cash and investment resources.
Fate Therapeutics (NASDAQ: FATE) announced that its Chief Scientific Officer, Dan Shoemaker, Ph.D., will present at the Wedbush PacGrow Healthcare Virtual Conference on August 12, 2020, at 11:30 a.m. EST. A live webcast will be available on the company's investor relations website, with an archived replay to follow.
The company focuses on developing programmed cellular immunotherapies for cancer and immune disorders, utilizing its proprietary induced pluripotent stem cell (iPSC) platform.
Fate Therapeutics has entered an exclusive license agreement with Baylor College of Medicine for alloimmune defense receptors, a revolutionary technology aimed at preventing immune rejection of allogeneic cell therapies. Recent preclinical data published in Nature Biotechnology demonstrates that engineered allogeneic CAR T cells equipped with these receptors successfully evade immune rejection and achieve long-lasting tumor eradication. This innovation could potentially address significant challenges in allogeneic therapies, enhancing their effectiveness while preserving the patient’s immune system.
Fate Therapeutics announced the closing of a public offering of 7,108,796 shares at $28.31 each, raising approximately $201.3 million. The offering included 927,324 shares from underwriters' options. Funds will support clinical trials, production of clinical candidates, and expansion of manufacturing operations. Additionally, the company plans to sell 1,766,160 shares to Johnson & Johnson Innovation for about $50 million. This move aligns with Fate's focus on developing advanced cellular immunotherapies.
Fate Therapeutics (NASDAQ: FATE) announced the pricing of a public offering of 6,181,562 shares at $28.31 each, aiming to raise approximately $175 million, with expected net proceeds of $164.2 million after fees. The funds will support clinical trials, product manufacturing, and facility expansion. Additionally, the company plans to sell 1,766,160 shares to Johnson & Johnson Innovation for about $50 million. The offering is set to close around June 11, 2020, subject to customary conditions.
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