Welcome to our dedicated page for CRISPR Therapeutics news (Ticker: CRSP), a resource for investors and traders seeking the latest updates and insights on CRISPR Therapeutics stock.
CRISPR Therapeutics AG (symbol: CRSP) is a pioneering gene editing company dedicated to the development of transformative gene-based medicines for serious diseases using its proprietary CRISPR/Cas9 platform. This revolutionary technology allows for precise, directed changes to genomic DNA, enabling the treatment of genetically defined diseases.
The company's portfolio spans a broad range of therapeutic programs, including hemoglobinopathies, oncology, regenerative medicine, and rare diseases. One of its notable achievements is the development and approval of Casgevy, a therapeutic targeting sickle cell disease and transfusion-dependent beta-thalassemia, developed in collaboration with Vertex Pharmaceuticals.
To bolster its research and development, CRISPR Therapeutics has forged strategic partnerships with renowned companies such as Bayer, Vertex Pharmaceuticals, and ViaCyte, Inc. These collaborations aim to accelerate and expand the company's efforts in bringing novel therapies to market.
Headquartered in Zug, Switzerland, CRISPR Therapeutics operates through its wholly-owned U.S. subsidiary, with R&D operations based in Cambridge, Massachusetts, and business offices in San Francisco, California, and London, United Kingdom.
The company's ongoing projects include advancing gene editing programs in immuno-oncology and developing stem cell-derived therapies for the treatment of Type 1 diabetes. With its innovative approach and strategic collaborations, CRISPR Therapeutics is at the forefront of the gene editing revolution, poised to make significant impacts in the field of medicine.
For more information, please visit www.crisprtx.com.
CRISPR Therapeutics (Nasdaq: CRSP) appointed Brendan Smith as Chief Financial Officer, effective immediately. Smith succeeds Michael Tomsicek, who is retiring after four years, and will assist in a smooth transition until the end of 2021. Smith brings over 20 years of experience, previously serving as CFO of Translate Bio, which was acquired by Sanofi for $3.2 billion. CEO Samarth Kulkarni highlighted Smith's expertise during a critical growth phase for CRISPR Therapeutics, which focuses on gene-based medicines for serious diseases using CRISPR/Cas9 technology.
CRISPR Therapeutics (CRSP) announced promising results from its Phase 1 CARBON trial, evaluating CTX110 for treating large B-cell lymphoma (LBCL). The trial reported a 58% overall response rate (ORR) and a 38% complete response (CR) rate in patients treated at Dose Level 2 and above, with durable responses noted over 18 months. The safety profile was favorable, showing no Grade 3 or higher cytokine release syndrome. CRISPR plans to expand the CARBON trial into a potentially registrational study in Q1 2022, supporting the development of CTX110 as an effective 'off-the-shelf' therapy.
CRISPR Therapeutics announced a virtual event scheduled for October 12, 2021, at 4:30 p.m. ET to discuss clinical data from its ongoing Phase 1 CARBON trial. This trial evaluates the safety and efficacy of CTX110, an investigational CAR-T therapy targeting CD19 for treating relapsed or refractory B-cell malignancies. Investors and stakeholders can join via a conference call or through a live webcast. CTX110 is a gene-edited allogeneic CAR-T therapy developed by CRISPR Therapeutics, focusing on significant diseases using their proprietary CRISPR/Cas9 technology.
CRISPR Therapeutics (Nasdaq: CRSP) announced two poster presentations and an oral presentation at the upcoming Society for Immunotherapy of Cancer (SITC) Annual Meeting, scheduled for November 10-14, 2021, in Washington, D.C. The first poster focuses on CRISPR/Cas9 gene-edited CAR-T cells targeting CD33 in acute myeloid leukemia (AML), demonstrating promising preclinical efficacy without long-term toxicity. The joint oral presentation with Nkarta will cover strategies to enhance NK cell efficacy against solid tumors. These presentations highlight CRISPR's commitment to advancing gene-based therapies.
CRISPR Therapeutics announced participation in Chardan’s 5th Annual Genetic Medicines Conference on October 4, 2021, at 2:00 p.m. ET. Senior management will present insights on their innovative gene-based medicines targeting serious diseases. A live webcast will be accessible via the Company's website, with a replay available for 14 days post-event. The company is noted for its leading gene editing technology, CRISPR/Cas9, and has collaborations with Bayer and Vertex Pharmaceuticals.
CRISPR Therapeutics (Nasdaq: CRSP) will participate in the Canaccord Genuity 41st Annual Growth Conference on August 12, 2021, at 2:30 p.m. ET. The event aims to showcase the company's advancements in gene-based medicines for serious diseases using its CRISPR/Cas9 platform. A live webcast will be available on the company's website, with a replay accessible for 14 days post-event. CRISPR Therapeutics specializes in various therapeutic areas, including oncology and rare diseases, and collaborates with leading firms like Bayer and Vertex Pharmaceuticals.
CRISPR Therapeutics (Nasdaq: CRSP) reported strong financial results for Q2 2021, highlighting a net income of $759.2 million, a significant increase from a $79.7 million loss in Q2 2020. The revenue surge to $900.2 million was primarily due to a $900 million upfront payment from Vertex following their collaboration amendment. The company has dosed over 45 patients with CTX001 in ongoing trials for sickle cell disease and beta thalassemia, with enrollment completion expected in Q3 2021. Additionally, CTX130 received Orphan Drug Designation for T-cell lymphoma.
CRISPR Therapeutics (CRSP) has announced a strategic partnership with Capsida Biotherapeutics to develop gene editing therapies targeting familial amyotrophic lateral sclerosis (ALS) and Friedreich’s ataxia. CRISPR will lead the Friedreich’s ataxia program, while Capsida will focus on ALS. The collaboration combines CRISPR's gene-editing technology with Capsida's advanced AAV engineering capabilities, potentially enhancing therapeutic efficacy. Both companies can co-develop and share commercialization costs and profits from their respective programs.
Vertex Pharmaceuticals and CRISPR Therapeutics announced positive results from their investigational CRISPR/Cas9 gene-editing therapy, CTX001, in treating transfusion-dependent beta thalassemia (TDT) and severe sickle cell disease (SCD). Data from 22 patients indicated sustained treatment responses, with all TDT patients transfusion-free and SCD patients free from vaso-occlusive crises. The therapy aims to provide a one-time functional cure for these conditions. Ongoing trials are expected to finalize regulatory discussions soon.
CRISPR Therapeutics (Nasdaq: CRSP) has announced participation in three virtual investor conferences in June 2021. The events include the Jefferies Virtual Healthcare Conference on June 1 at 1:00 p.m. ET, the William Blair 41st Annual Growth Stock Conference on June 3 at 12:20 p.m. ET, and the Goldman Sachs 42nd Annual Global Healthcare Conference on June 8 at 3:00 p.m. ET. Live webcasts of these presentations will be accessible on the company's website, and recordings will be available for 14 days post-event.
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