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CRISPR Therapeutics AG (symbol: CRSP) is a pioneering gene editing company dedicated to the development of transformative gene-based medicines for serious diseases using its proprietary CRISPR/Cas9 platform. This revolutionary technology allows for precise, directed changes to genomic DNA, enabling the treatment of genetically defined diseases.
The company's portfolio spans a broad range of therapeutic programs, including hemoglobinopathies, oncology, regenerative medicine, and rare diseases. One of its notable achievements is the development and approval of Casgevy, a therapeutic targeting sickle cell disease and transfusion-dependent beta-thalassemia, developed in collaboration with Vertex Pharmaceuticals.
To bolster its research and development, CRISPR Therapeutics has forged strategic partnerships with renowned companies such as Bayer, Vertex Pharmaceuticals, and ViaCyte, Inc. These collaborations aim to accelerate and expand the company's efforts in bringing novel therapies to market.
Headquartered in Zug, Switzerland, CRISPR Therapeutics operates through its wholly-owned U.S. subsidiary, with R&D operations based in Cambridge, Massachusetts, and business offices in San Francisco, California, and London, United Kingdom.
The company's ongoing projects include advancing gene editing programs in immuno-oncology and developing stem cell-derived therapies for the treatment of Type 1 diabetes. With its innovative approach and strategic collaborations, CRISPR Therapeutics is at the forefront of the gene editing revolution, poised to make significant impacts in the field of medicine.
For more information, please visit www.crisprtx.com.
CRISPR Therapeutics (Nasdaq: CRSP) will host an Innovation Day on June 21, 2022, at 2:00 PM ET, focusing on its advanced research in genetic engineering and cell therapy. The event will showcase the company's innovative platform technologies and new discovery programs. A live webcast will be available on the company's website, with the recording archived for 30 days post-event. CRISPR Therapeutics is committed to developing transformative gene-based medicines targeting serious diseases, leveraging its proprietary CRISPR/Cas9 technology.
CRISPR Therapeutics (Nasdaq: CRSP) has appointed Dr. Phuong Khanh (P.K.) Morrow as Chief Medical Officer, effective May 23, 2022. Dr. Morrow brings over a decade of experience in global drug development, particularly in oncology, and will oversee the company's clinical development and regulatory operations. The leadership change aims to enhance CRISPR’s innovative gene-editing therapies. CEO Samarth Kulkarni emphasized her expertise will be essential in advancing their clinical strategy and building the organization.
CRISPR Therapeutics (Nasdaq: CRSP) announced that an abstract detailing safety and efficacy data from the ongoing CTX130 clinical trial for T-cell lymphoma has been accepted for oral presentation at the EHA 2022 Hybrid Congress, taking place June 9-12, 2022. This marks the first presentation of clinical data from the CTX130 program. The abstract, titled The COBALT-LYM Study of CTX130, will be presented by Dr. Swaminathan P. Iyer on June 11, 2022. CTX130 is a gene-edited CAR-T therapy targeting CD70, being investigated in two Phase 1 trials for relapsed/refractory malignancies.
CRISPR Therapeutics (CRSP) reported Q1 2022 financial results, highlighting significant progress in clinical trials. Key milestones include dosing over 75 patients with CTX001 in ongoing Phase 3 trials for beta thalassemia and sickle cell disease, with global regulatory submissions anticipated in late 2022. R&D expenses rose to $118.2 million, reflecting ongoing advancements in its immuno-oncology pipeline. Cash reserves stood at $2.22 billion, down from $2.38 billion in Q4 2021. Net loss for the quarter was $179.2 million, compared to $113.2 million a year prior.
CRISPR Therapeutics (Nasdaq: CRSP) announced its senior management team will participate in the 2022 Bank of America Healthcare Conference on May 11, 2022, at 4:40 p.m. PT. A live webcast will be available on the Company's Investors section of the website, with a replay accessible for 14 days post-event. The company focuses on gene-based medicines to tackle serious diseases using its innovative CRISPR/Cas9 platform. CRISPR Therapeutics operates in multiple therapeutic areas, including oncology and rare diseases, with collaborations alongside industry leaders like Bayer and Vertex Pharmaceuticals.
CRISPR Therapeutics (Nasdaq: CRSP) has announced the proposed election of Maria Fardis, Ph.D., MBA, to its Board of Directors at the upcoming annual general meeting. With a strong background in biopharmaceuticals, including her leadership at Iovance Biotherapeutics and Acerta Pharma, Dr. Fardis is expected to enhance the company's ability to advance its gene-based medicines pipeline. CEO Samarth Kulkarni highlighted her extensive experience as a valuable asset for CRISPR Therapeutics as it seeks to address serious medical conditions.
CRISPR Therapeutics (Nasdaq: CRSP) announced participation in three key investor conferences in April 2022. These include the 21st Annual Needham Virtual Healthcare Conference on April 12 at 12:45 PM ET, the Canaccord Genuity Horizons in Oncology Virtual Conference on April 14 at 1:00 PM ET, and the 14th Kempen Life Sciences Conference in Amsterdam on April 20 at 3:30 PM CET. Live webcasts will be accessible on the company's website, with a 14-day replay available post-event.
CRISPR Therapeutics focuses on gene-based medicines for serious diseases using its innovative CRISPR/Cas9 technology.
CRISPR Therapeutics (Nasdaq: CRSP) will present an e-poster at the AACR 2022 Annual Meeting from April 8-13, 2022, highlighting its innovative cancer immunotherapy research. The presentation titled “CBLB, CISH and CD70 multiplexed gene knockout with CRISPR/Cas9 enhances cytotoxicity of CD70-CAR NK cells” is set for April 8, 2022. This research emphasizes the potential of CRISPR/Cas9 technology in advancing cancer treatments. As a leader in gene editing, CRISPR Therapeutics aims to develop transformative therapies for serious diseases, collaborating with major firms like Bayer and Vertex Pharmaceuticals.
CRISPR Therapeutics (Nasdaq: CRSP) has announced its participation in several investor conferences in March 2022. The schedules are as follows:
- Cowen 42nd Annual Health Care Conference on March 7 at 10:30 a.m. ET.
- Barclays Global Healthcare Conference on March 17 at 10:15 a.m. ET.
- Oppenheimer 32nd Annual Healthcare Conference on March 24 at 11:00 a.m. ET.
Live webcasts will be available on the company's website, with replays accessible for 14 days post-event.
CRISPR Therapeutics (Nasdaq: CRSP) reported a productive 2021, advancing its gene-editing therapies. More than 70 patients have been dosed with CTX001 for beta thalassemia and sickle cell disease, with regulatory submissions expected in late 2022. The company initiated the pivotal trial for CTX110 targeting B-cell malignancies, expecting further data this year. Financially, total revenue surged to $913.1 million from $0.5 million YoY, driven by Vertex collaborations. However, net loss widened to $141.2 million in Q4 2021, emphasizing the costs of R&D investments.
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