Cellectis Stock Price, News & Analysis

Cellectis S.A. (NASDAQ: CLLS) has announced Calyxt, its subsidiary, reported first-quarter 2022 results. Calyxt generated nominal revenue due to the discontinuation of its soybean product line, down from $4.4 million in Q1 2021. Operating expenses fell to $6.1 million, resulting in a net loss of $5.6 million compared to $10.0 million in the previous year. Calyxt's advancements include evaluating 28 customer-identified molecules and enhancing its BioFactory production capabilities, as well as raising $10 million from a stock offering, which will support technology scaling and customer engagement.

Cellectis has published promising preclinical data regarding its gene-edited CAR T-cell therapy candidate, UCART123, targeting acute myeloid leukemia (AML) and blastic plasmacytoid dendritic cell neoplasm (BPDCN). Results demonstrate that UCART123 effectively eliminates AML cells with minimal impact on normal hematopoietic progenitor cells, supporting its clinical evaluation in the ongoing Phase 1 AMELI-01 trial. The therapy has shown potent anti-BPDCN activity and improved overall survival in patient-derived models, enhancing its potential as a treatment option for patients with unmet medical needs.

Cellectis has announced a collaboration with Cytovia Therapeutics, which has entered into a business combination agreement with Isleworth Healthcare Acquisition Corp. The deal, expected to list the combined company under the ticker INKC on NASDAQ, includes a $20 million convertible note as part of Cellectis' upfront consideration. The agreement stems from their ongoing partnership to develop gene-edited Natural Killer cells using Cellectis' TALEN® technology. Financial terms also encompass potential milestone payments totaling up to $805 million, alongside royalty payments on net sales.

Cellectis announced promising preclinical data for its allogeneic dual CAR T-cell candidate, UCART20x22, targeting relapsed or refractory Non-Hodgkin Lymphoma (r/r NHL). The data demonstrate significant in vitro and in vivo anti-tumor activity, potentially overcoming common resistance mechanisms. UCART20x22 aims to simplify treatment by being fully developed and manufactured in-house, with an Investigational New Drug application expected this year. This marks a pivotal step in Cellectis’ strategy as it transitions to a comprehensive cell and gene therapy platform.

Cellectis, a clinical-stage biotechnology company, reported its share structure as of March 31, 2022. The company has a total of 45,490,810 shares in capital and 51,083,431 voting rights. Cellectis utilizes its gene-editing platform to develop therapies for various cancers and genetic disorders. Its UCART product candidates target diseases like acute myeloid leukemia and multiple myeloma. The company's commitment is to provide innovative therapies using its proprietary technologies, including TALEN® and PulseAgile.

Cellectis, a clinical-stage biotechnology company focused on gene editing, announced its participation in two important healthcare conferences: the Oppenheimer & Co. Annual Healthcare Conference on March 16, 2022, at 4:00 PM EST, and the Barclays Global Healthcare Conference on March 17, 2022, at 9:30 AM EST. Both events will feature live webcasts available on their investor website. Cellectis aims to advance its innovative CAR-T therapies, targeting diseases like leukemia and multiple myeloma, utilizing its proprietary gene-editing technology TALEN®.

Cellectis, a clinical-stage biotechnology company, specializes in gene-editing for cancer therapies. As of February 28, 2022, the company has a total of 45,484,310 shares in capital and 51,076,931 voting rights. Utilizing its TALEN® technology and PulseAgile system, Cellectis aims to develop allogeneic CAR-T immunotherapies for various cancers, including AML and B-ALL. The company is committed to addressing unmet medical needs in oncology and blood disorders.

Cellectis (Nasdaq: CLLS) reported its fourth quarter and full-year 2021 results, highlighting a consolidated cash position of $191 million as of December 31, 2021, down from $274 million in 2020. The company experienced a consolidated revenue decrease to $67 million from $82 million in 2020. R&D expenses rose significantly to $129 million from $87 million. Cellectis presented encouraging preliminary results for its BALLI-01 study of UCART22 at ASH 2021, with plans for an IND submission for UCART20x22 in 2022. A conference call is scheduled for March 4, 2022, to discuss results.

Cellectis (Euronext Growth: ALCLS - Nasdaq: CLLS), a biotechnology firm specializing in gene editing, will announce its financial results for the fourth quarter and the year-end 2021 on March 3, 2022, after market closure. This will be followed by a conference call on March 4, 2022, at 8:00 AM EDT, detailing its quarterly and annual results and business updates. Cellectis focuses on innovative cell and gene therapies for cancer and blood disorders, utilizing its TALEN® technology and PulseAgile electroporation system.