Welcome to our dedicated page for Cellectis S.A. American Depositary Shares news (Ticker: CLLS), a resource for investors and traders seeking the latest updates and insights on Cellectis S.A. American Depositary Shares stock.
Cellectis S.A. (symbol: CLLS) is a clinical-stage biopharmaceutical company that specializes in developing cutting-edge cancer immunotherapies using gene-edited T-cells, known as UCART. With over 18 years of experience in gene editing, Cellectis leverages its proprietary TALEN® technology and PulseAgile electroporation system to harness the power of the immune system to combat cancer.
Cellectis is dedicated to creating innovative products in the fields of immuno-oncology and beyond. Its portfolio includes allogeneic Chimeric Antigen Receptor T-cells (CAR-T) product candidates and gene-edited hematopoietic stem and progenitor cells (HSPC) for various therapeutic applications.
Recent achievements include advancements in gene correction and gene insertion technologies, presented at esteemed scientific conferences. For instance, the company has introduced a novel method for circularizing non-viral single-strand DNA templates, enhancing gene editing outcomes in HSPCs. Cellectis is also collaborating with renowned pharmaceutical companies like AstraZeneca, further expanding its pipeline of allogeneic CAR T-cell therapies.
Financially, Cellectis is listed on both the NASDAQ (ticker: CLLS) and the NYSE Alternext (ticker: ALCLS) markets. The company's ongoing projects and research efforts are supported by robust investment and partnership agreements, showcasing its commitment to improving health outcomes through innovative biotechnological solutions.
For more information, visit the company's website at www.cellectis.com.
Cellectis, a gene editing company, reported its share and voting rights on November 30, 2021, with a total of 45,477,810 shares and 51,079,282 voting rights. The company focuses on CAR-T immunotherapies and gene editing technologies for cancer treatment. Headquartered in Paris, Cellectis is listed on both Nasdaq (CLLS) and Euronext Growth (ALCLS). The firm targets various cancers, utilizing its TALEN® technology and the PulseAgile system, aiming to address unmet medical needs. For more details, visit www.cellectis.com.
Cytovia Therapeutics has expanded its collaboration with Cellectis to develop gene-edited NK and CAR-NK cells, enhancing cancer treatment options. The agreement includes $20 million in equity for Cytovia and up to $805 million in potential milestones. This strategic partnership also grants Cytovia exclusive rights to modify NK cells using TALEN® technology, facilitating advancement in various cancer indications, particularly in China through their joint venture, CytoLynx Therapeutics. The collaboration aims to leverage innovative immunotherapies targeting unmet medical needs.
Cellectis S.A. (NASDAQ: CLLS) announced significant preclinical data for UCARTMESO, its allogeneic CAR-T cell product candidate targeting mesothelin for the treatment of solid tumors. The data presented at SITC's 36th Annual Meeting indicate that mesothelin is a promising target for CAR-T therapy due to its high expression in certain cancers. UCARTMESO demonstrated potent activity in vitro and in mouse models of pancreatic and pleural mesothelioma. The knockout of TGFBR2 genes enhances its effectiveness even in immunosuppressive tumor environments, suggesting a potential breakthrough in solid tumor treatment.
Cellectis announced its share and voting rights update as of October 31, 2021. The total number of shares in circulation is 45,475,310, while the total number of voting rights stands at 51,076,779. As a gene editing company, Cellectis focuses on CAR-T therapies for oncology and has 21 years of expertise in the field. Its approach includes off-the-shelf gene-edited CAR T-cells and a new platform targeting hemopoietic stem cells for various diseases. Cellectis is listed on Nasdaq (ticker: CLLS) and Euronext Growth (ticker: ALCLS).
Cellectis S.A. reported a cash position of $216 million as of September 30, 2021, down from $274 million at year-end 2020. The company generated $11 million in revenues for Q3 2021, reflecting an increase from $9 million in Q3 2020, but a decrease to $53 million for the first nine months of 2021 compared to $67 million in the same period of 2020. R&D expenses rose to $34 million in Q3 2021, up from $20 million in Q3 2020. The net loss attributable to shareholders was $37 million for Q3 2021, compared to $30 million in Q3 2020. Preliminary clinical data will be presented at ASH 2021.
Cellectis, a gene-editing company, announced two abstracts accepted for presentation at the 63rd ASH Annual Meeting from December 11-14, 2021. They will share updated preliminary data from the BALLI-01 clinical trial involving UCART22 for relapsed/refractory B-cell acute lymphoblastic leukemia, and preclinical data on TALGlobin01 for sickle cell disease. The BALLI-01 trial data indicates good tolerance and CAR-T cell expansion. TALGlobin01 shows promise in correcting the mutated beta-globin gene, marking significant progress in gene therapy.
Cellectis S.A. (NASDAQ: CLLS) announced it will report its financial results for Q3 and the first nine months of 2021 after market close on November 4, 2021. A conference call is scheduled for November 5, 2021, at 8:00 AM EDT. The company focuses on gene editing technologies, particularly in developing CAR-T cell therapies for cancer and gene therapy programs for genetic disorders. Cellectis aims to provide life-saving treatments for various cancers and genetic diseases.
Cellectis (NASDAQ: CLLS) announced the upcoming presentation of pre-clinical data on its UCARTMESO product candidate at the Society for Immunotherapy of Cancer’s Annual Meeting, scheduled for November 10-14, 2021. UCARTMESO targets mesothelin-expressing solid tumors, leveraging TALEN® gene editing technology to enhance anti-tumor activity. The poster presentation will occur on November 12, focusing on engineered CAR-T cells designed to overcome tumor immunosuppression. Cellectis aims to advance its CAR-T immunotherapy programs and explore new therapeutic avenues.
Cellectis, a clinical-stage biopharmaceutical firm specializing in gene editing, reported its total shares and voting rights as of September 30, 2021. The company has 45,465,310 shares and 51,066,417 voting rights. Cellectis focuses on developing CAR-T immunotherapies and innovative therapeutic products aimed at treating various cancers, including AML and B-ALL, through its unique TALEN® technology. The company is committed to addressing unmet medical needs in oncology and hematological disorders.
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