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Cellectis - CLLS STOCK NEWS

Welcome to our dedicated page for Cellectis news (Ticker: CLLS), a resource for investors and traders seeking the latest updates and insights on Cellectis stock.

Cellectis S.A. (NASDAQ: CLLS) is a clinical-stage biopharmaceutical leader developing groundbreaking allogeneic CAR-T therapies through precision gene-editing technologies. This page provides investors and industry professionals with essential updates on the company’s clinical trials, regulatory milestones, and strategic developments.

Access real-time announcements including FDA submissions, partnership agreements, and research breakthroughs. Our curated collection features press releases on TALEN®-engineered therapies, hematopoietic stem cell advancements, and financial results – all critical for evaluating this innovator in off-the-shelf cancer treatments.

Key updates cover three focus areas: clinical trial phases for UCART candidates, intellectual property developments, and collaborative research initiatives. Bookmark this page to monitor progress in scalable cancer immunotherapies and maintain informed perspectives on Cellectis’ position within the competitive gene-editing landscape.

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Cellectis, a clinical-stage biotechnology company focused on gene editing, announced an underwritten offering to an institutional investor involving Calyxt, its majority-owned subsidiary. The offering includes 3,880,000 shares of Calyxt common stock, pre-funded warrants for 3,880,000 shares, and common warrants for 7,760,000 shares, all priced at $1.41 each. As of December 31, 2021, Calyxt reported cash and cash equivalents of $13.7 million and total current liabilities of $4.1 million. The preliminary financial data is subject to audits and potential adjustments.

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Cellectis, a clinical-stage biotechnology company, focuses on gene editing and cell therapies for cancer treatment. As of January 31, 2022, the total number of shares outstanding is 45,484,310, with 51,085,785 voting rights. The company aims to provide lifesaving UCART products targeting multiple cancers and has developed a new platform, .HEAL, for treating blood disorders. Cellectis strives to leverage its TALEN® technology and PulseAgile system for innovative therapies. It is listed on both Nasdaq (CLLS) and Euronext Growth (ALCLS).

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Cellectis has appointed Bing C. Wang, PhD, MBA, as the new Chief Financial Officer. Wang brings extensive experience in biotechnology finance, previously serving as CEO of Refuge Biotechnologies and in investment banking with Barclays and Citigroup. He will manage Cellectis’ global finance team, aiming to enhance the company’s financial strategy during its clinical trial developments. Wang's background includes strategic capital raising and corporate finance, making him a valuable addition to Cellectis as it focuses on developing off-the-shelf cancer therapies.

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Cellectis announced its share and voting rights status as of December 31, 2021. The total number of shares in capital stood at 45,484,810, while the total number of voting rights reached 51,085,782. The company specializes in gene editing and is known for its innovative CAR-T immunotherapies aimed at treating various cancers, including acute myeloid leukemia and multiple myeloma. Cellectis operates from its headquarters in Paris and has a presence in New York and North Carolina. Its commitment to developing life-saving therapies positions it as a leader in the biotech sector.

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Cellectis (Nasdaq: CLLS) reported that the FDA has lifted the clinical hold on its partner Allogene Therapeutics’ clinical trials, enabling the resumption of studies for ALLO-501A, an anti-CD19 CAR-T cell therapy. This decision follows investigations revealing that a chromosomal abnormality found in a single patient was unrelated to TALEN® gene editing or Allogene’s manufacturing process. The abnormality's clinical significance was deemed negligible.

Allogene plans to start a pivotal Phase 2 trial for ALLO-501A in relapsed/refractory large B-cell lymphoma by mid-2022.

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Cellectis (Nasdaq: CLLS) announced its 2022 business objectives, focusing on ongoing clinical trials BALLI-01, AMELI-01, and MELANI-01. The company aims to enroll patients in these trials and file an IND for UCART20x22, its first dual allogeneic CAR-T product. Cellectis has operational manufacturing sites in Raleigh and Paris, projecting its cash runway into early 2024 with $201 million available as of September 30, 2021. The company is committed to advancing its pipeline of life-saving cell and gene therapies.

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Cellectis announced preliminary results from the BALLI-01 Phase 1 study of UCART22, targeting relapsed/refractory B-cell acute lymphoblastic leukemia (r/r B-ALL). The study demonstrated that UCART22 can be administered safely after lymphodepletion with FCA, showing no dose-limiting toxicities. Encouraging anti-leukemic activity was observed in 2 out of 6 patients, with one achieving blast reduction to 0%. The trial is currently enrolling at dose level 3. Additionally, preclinical data for TALGlobin01 showed efficient correction of the mutated beta-globulin gene for sickle cell disease.

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Cellectis, a gene editing company, reported its share and voting rights on November 30, 2021, with a total of 45,477,810 shares and 51,079,282 voting rights. The company focuses on CAR-T immunotherapies and gene editing technologies for cancer treatment. Headquartered in Paris, Cellectis is listed on both Nasdaq (CLLS) and Euronext Growth (ALCLS). The firm targets various cancers, utilizing its TALEN® technology and the PulseAgile system, aiming to address unmet medical needs. For more details, visit www.cellectis.com.

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Cytovia Therapeutics has expanded its collaboration with Cellectis to develop gene-edited NK and CAR-NK cells, enhancing cancer treatment options. The agreement includes $20 million in equity for Cytovia and up to $805 million in potential milestones. This strategic partnership also grants Cytovia exclusive rights to modify NK cells using TALEN® technology, facilitating advancement in various cancer indications, particularly in China through their joint venture, CytoLynx Therapeutics. The collaboration aims to leverage innovative immunotherapies targeting unmet medical needs.

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Cellectis S.A. (NASDAQ: CLLS) announced significant preclinical data for UCARTMESO, its allogeneic CAR-T cell product candidate targeting mesothelin for the treatment of solid tumors. The data presented at SITC's 36th Annual Meeting indicate that mesothelin is a promising target for CAR-T therapy due to its high expression in certain cancers. UCARTMESO demonstrated potent activity in vitro and in mouse models of pancreatic and pleural mesothelioma. The knockout of TGFBR2 genes enhances its effectiveness even in immunosuppressive tumor environments, suggesting a potential breakthrough in solid tumor treatment.

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Nasdaq:CLLS

CLLS Rankings

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145.42M
69.31M
3.87%
20.71%
0.24%
Biotechnology
Healthcare
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France
Paris