C4 Therapeutics, Inc. Stock Price, News & Analysis

C4 Therapeutics (Nasdaq: CCCC) reported a revenue decline to $31.1 million for the year ended December 31, 2022, down from $45.8 million in 2021, primarily due to a one-time recognition in the prior year. R&D expenses increased to $117.8 million from $94.7 million, driven by clinical activities. The company posted a net loss of $128.2 million and net loss per share of $2.62, compared to $83.9 million and $1.82, respectively. Despite the financial challenges, C4T anticipates a cash runway until the end of 2024 and is focusing on advancing multiple clinical trials, with important data expected in 2H 2023.

C4 Therapeutics, Inc. (Nasdaq: CCCC), a clinical-stage biopharmaceutical firm, announced its participation in two virtual conferences in February 2023. The SVB Securities Global Biopharma Conference will feature a fireside chat on February 15 at 3:00 PM ET, while a panel discussion titled Key Targets for Targeted Protein Degradation in Oncology is scheduled for February 21 at 12:00 PM ET during the 2023 Wells Fargo Targeted Protein Degradation Summit. Live webcasts will be accessible on the company’s website, with archived replays available for 30 days. C4T is focused on targeted protein degradation to develop innovative therapies for challenging diseases.

C4 Therapeutics, Inc. (Nasdaq: CCCC) announced the first patient has been dosed in its Phase 1/2 clinical trial for CFT1946, a targeted therapy for BRAF V600 mutant solid tumors. This marks the first degrader to enter clinical development aimed at BRAF-driven cancers, generally treated with limited options once resistance develops. Early studies indicate CFT1946 may offer deeper and more durable efficacy than current BRAF inhibitors. The trial will assess safety and effectiveness, progressing to evaluate CFT1946 both alone and with trametinib in advanced phases. This initiative expands C4T's oncology programs via its proprietary TORPEDO® platform.

C4 Therapeutics (Nasdaq: CCCC) reports continued progress in its oncology trials, with key updates expected in 2023. The company is advancing CFT7455 and CFT8634, focusing on multiple myeloma and synovial sarcoma treatments. Phase 1 dose escalation data for both drugs will be shared in the second half of 2023. Additionally, CFT1946 targeting BRAF-V600 mutations has initiated trials. As of September 30, 2022, C4T holds $366 million in cash, enough to fund operations into 2024. A presentation at the J.P. Morgan Healthcare Conference is also scheduled.

C4 Therapeutics (Nasdaq: CCCC), a clinical-stage biopharmaceutical company, announced its participation in the 41st Annual J.P. Morgan Healthcare Conference on January 9, 2023, at 10:30 am PST (1:30 pm EST) in San Francisco. The event will be accessible via a live webcast on the company’s website, with a replay available for two weeks afterward. C4T focuses on targeted protein degradation to develop innovative medicines for difficult-to-treat diseases, leveraging its TORPEDO® platform to enhance patient outcomes.

C4 Therapeutics (Nasdaq: CCCC) reported a net loss of $32 million for Q3 2022 compared to $24.7 million in Q3 2021. Total revenue decreased to $6.8 million from $8.5 million, driven by collaborative agreements. R&D expenses rose to $29.7 million, primarily due to ongoing clinical trials for CFT7455 and CFT8634. They achieved IND clearance for CFT1946, a significant milestone expected to lead to Phase 1/2 trial initiation by year-end. Cash and marketable securities as of September 30, 2022, stood at $366 million, sufficient to fund operations until the end of 2024.

C4 Therapeutics (Nasdaq: CCCC) has received FDA approval to proceed with a Phase 1/2 trial for its drug CFT1946, targeting BRAF-V600 mutant solid tumors like lung, colorectal, and melanoma. This marks C4T's third successful oncology investigational new drug application in under two years. CFT1946 aims to provide deeper and more durable responses compared to existing BRAF inhibitor treatments. The trial will primarily assess safety, tolerability, and anti-tumor activity, with initial evaluations involving CFT1946 as a single agent and later in combination with trametinib.

C4 Therapeutics (Nasdaq: CCCC) announced participation in the Bank of America Securities Precision Oncology Conference 2022. The event will occur on October 3, 2022, at 9:50 a.m. ET. C4T focuses on advancing targeted protein degradation science to develop innovative small-molecule medicines aimed at improving patient outcomes in oncology. The presentation will be available via live webcast on the company's website, with an archived replay accessible for 30 days post-event. C4T is leveraging its TORPEDO® platform to tackle challenging diseases.

C4 Therapeutics (Nasdaq: CCCC) reported a 40% increase in total revenue to $13.8 million for Q2 2022, up from $9.8 million in Q2 2021, driven by collaboration agreements. The company incurred a net loss of $27.4 million, leading to a net loss per share of $0.56. C4T continues to advance its pipeline with CFT7455 and CFT8634 in Phase 1/2 trials. The company maintains a strong cash position of $397.8 million, projected to fund operations through the end of 2024.