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Arvinas, Inc - ARVN STOCK NEWS

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Arvinas, Inc. (Nasdaq: ARVN) is a clinical-stage biopharmaceutical company focused on developing innovative therapies to treat debilitating and life-threatening diseases through the degradation of disease-causing proteins. The company's proprietary PROTAC® Discovery Engine platform creates Proteolysis-Targeting Chimeras (PROTACs), which leverage the cell's natural protein disposal system to target and degrade specific proteins involved in various diseases.

Founded on groundbreaking research from Yale University by Dr. Craig Crews, Arvinas is at the forefront of transforming protein degradation into novel therapeutic strategies. Their lead candidates include bavdegalutamide (ARV-110) and ARV-766, aimed at treating metastatic castration-resistant prostate cancer, and vepdegestrant (ARV-471), which targets estrogen receptor-positive (ER+)/human epidermal growth factor receptor 2-negative (HER2-) breast cancer.

Recent achievements highlight Arvinas' robust pipeline and strategic partnerships. In collaboration with Pfizer, vepdegestrant is undergoing Phase 3 trials, showing promising clinical activity and safety in heavily pre-treated breast cancer patients. The company has also initiated a strategic license agreement with Novartis for the global development and commercialization of ARV-766, affirming its potential as a first-in-class treatment for prostate cancer.

Financially, Arvinas maintains a strong position with sufficient resources to fund operations into 2027, bolstered by strategic collaborations and revenue from ongoing license agreements. The company's focus on expanding its clinical trials and exploring new combination therapies positions it for significant impact in oncology and beyond.

For the latest updates on Arvinas' developments and clinical trials, visit their website at www.arvinas.com.

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Arvinas, a clinical-stage biotechnology company focused on targeted protein degradation, announced participation in three investor conferences. The events include the Guggenheim Oncology Conference on February 9, featuring a fireside chat with Chief Medical Officer Ron Peck and CFO Sean Cassidy. The SVB Leerink Global Healthcare Conference on February 16 will include Ron Peck and Randy Teel, Senior VP of Corporate Development. Finally, the Citi Oncology Leadership Summit on February 23 will feature Chief Scientific Officer Ian Taylor. Live audio webcasts will be available for each presentation on the company’s website.

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Arvinas, a clinical-stage biotechnology company, will present an overview at the 41st Annual J.P. Morgan Healthcare Conference on January 11, 2023, at 1:30 p.m. PT in San Francisco. CEO John Houston will lead the presentation, focusing on the company's innovative approach to targeted protein degradation. Arvinas utilizes its proprietary PROTAC® Discovery Engine to develop therapies aimed at devastating diseases, including investigational programs for metastatic prostate and breast cancer. A live audio webcast of the presentation will be available online.

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Arvinas, a clinical-stage biotechnology firm, announces the resignation of Brad Margus from its Board, with Everett Cunningham appointed as his replacement. Margus was a valued member of the Audit Committee, contributing significantly to Arvinas' development. Cunningham brings over 25 years of experience in pharmaceuticals, previously holding key roles at Exact Sciences and GE Healthcare. With expertise in commercialization and a strong background in medical services, Cunningham is expected to enhance Arvinas’ transition into late-stage development and improve patient outcomes.

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ARV-471, a novel PROTAC® estrogen receptor degrader, exhibits promising activity in patients with advanced ER+/HER2- breast cancer, achieving a median progression-free survival of 3.7 months overall and 5.7 months in patients with ESR1 mutant tumors. A clinical benefit rate of 38% was recorded in a heavily pre-treated cohort. Initial results from the VERITAC trial support the initiation of two Phase 3 trials. The study emphasizes ARV-471's favorable tolerability profile and potential as a new standard of care, with plans to initiate pivotal trials in late 2022 and early 2023.

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Arvinas, Inc. (Nasdaq: ARVN) reported its third-quarter financial results for 2022, highlighting significant progress in clinical trials and executive team enhancements. The company is set to initiate two Phase 3 trials of ARV-471 for metastatic breast cancer by the year's end. Financially, revenues climbed to $30.3 million from $9.3 million in Q3 2021, driven by the ARV-471 collaboration. However, the net loss rose to $66.2 million, up from $46.8 million year-over-year, primarily due to increased R&D and administrative expenses.

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Arvinas, a clinical-stage biotechnology company, will present at two key conferences in November 2022. At the Society for Neuroscience Annual Meeting, Angela Cacace will showcase research on PROTAC® molecules targeting neurodegenerative proteins on November 12. Additionally, Arvinas will participate in the Stifel Healthcare Conference with Ron Peck and Randy Teel engaging in a fireside chat on November 15. The company focuses on innovative therapies that degrade disease-causing proteins, currently advancing multiple clinical-stage programs, including treatments for prostate and breast cancer.

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Arvinas, Inc. (Nasdaq: ARVN) announced the appointment of Paul McInulty as Senior Vice President of Regulatory Affairs, effective October 3, 2022. McInulty brings over 25 years of biopharmaceutical experience, having previously held key roles at Bristol Myers Squibb and Celgene Corporation. His expertise will support Arvinas' transition into a late-stage development company focused on targeted protein degradation therapies. With a robust pipeline, including investigational programs for metastatic prostate and breast cancer, Arvinas aims to leverage McInulty’s experience to enhance regulatory strategies and overall growth trajectory.

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On September 30, 2022, Arvinas, a clinical-stage biotechnology company, held its inaugural “Arvinas Impact Day,” with nearly 200 employees volunteering in the Greater New Haven area. The event emphasized community service, focusing on STEM initiatives and environmental protection. Highlights included educating over 300 students on financial literacy, enhancing facilities for a non-profit organization, and cleaning local beaches. CEO John Houston emphasized the company's commitment to community engagement and expressed enthusiasm for future initiatives.

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Arvinas, a clinical-stage biotechnology company focused on targeted protein degradation, announced participation in a fireside chat at the Bank of America Securities Precision Oncology Conference on October 3, 2022, at 10:40 a.m. ET. The event will be accessible via a live audio webcast on Arvinas' website. The company is known for its innovative PROTAC® platform, which develops therapies aimed at degrading disease-causing proteins. Arvinas has several clinical-stage programs targeting prostate and breast cancers, reinforcing its commitment to advancing treatment options for severe diseases.

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FAQ

What is the current stock price of Arvinas (ARVN)?

The current stock price of Arvinas (ARVN) is $18.48 as of December 20, 2024.

What is the market cap of Arvinas (ARVN)?

The market cap of Arvinas (ARVN) is approximately 1.2B.

What does Arvinas, Inc. specialize in?

Arvinas specializes in developing therapies that degrade disease-causing proteins using their proprietary PROTAC® platform.

What are Arvinas' lead product candidates?

Arvinas' lead candidates include bavdegalutamide (ARV-110) and ARV-766 for prostate cancer, and vepdegestrant (ARV-471) for ER+/HER2- breast cancer.

What recent partnerships has Arvinas entered?

Arvinas has partnered with Pfizer for the co-development of vepdegestrant and entered a strategic license agreement with Novartis for ARV-766.

What financial position does Arvinas hold for its future operations?

Arvinas has a strong financial position, with sufficient resources to fund operations into 2027, supported by strategic collaborations and ongoing revenue.

What is PROTAC®?

PROTAC® stands for Proteolysis-Targeting Chimeras, a technology that leverages the cell’s natural protein disposal system to target and degrade specific proteins.

How does vepdegestrant (ARV-471) work?

Vepdegestrant (ARV-471) is designed to degrade the estrogen receptor in ER+/HER2- breast cancer, using the PROTAC® mechanism to harness the body's protein disposal system.

What are the key achievements of Arvinas recently?

Key achievements include initiating Phase 3 trials for vepdegestrant, strategic collaboration with Pfizer, and a license agreement with Novartis for ARV-766.

What is the significance of Arvinas' collaboration with Pfizer?

The collaboration with Pfizer aims to co-develop and commercialize vepdegestrant, leveraging both companies' expertise to bring new cancer treatments to market.

What diseases is Arvinas targeting with its therapies?

Arvinas is targeting various cancers, including prostate cancer and breast cancer, through the degradation of disease-causing proteins.

Where can I find more information about Arvinas?

More information about Arvinas can be found on their official website at www.arvinas.com.

Arvinas, Inc

Nasdaq:ARVN

ARVN Rankings

ARVN Stock Data

1.22B
62.43M
7.22%
109.24%
12.43%
Biotechnology
Pharmaceutical Preparations
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United States of America
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