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Arvinas, Inc. (Nasdaq: ARVN) is a clinical-stage biopharmaceutical company focused on developing innovative therapies to treat debilitating and life-threatening diseases through the degradation of disease-causing proteins. The company's proprietary PROTAC® Discovery Engine platform creates Proteolysis-Targeting Chimeras (PROTACs), which leverage the cell's natural protein disposal system to target and degrade specific proteins involved in various diseases.
Founded on groundbreaking research from Yale University by Dr. Craig Crews, Arvinas is at the forefront of transforming protein degradation into novel therapeutic strategies. Their lead candidates include bavdegalutamide (ARV-110) and ARV-766, aimed at treating metastatic castration-resistant prostate cancer, and vepdegestrant (ARV-471), which targets estrogen receptor-positive (ER+)/human epidermal growth factor receptor 2-negative (HER2-) breast cancer.
Recent achievements highlight Arvinas' robust pipeline and strategic partnerships. In collaboration with Pfizer, vepdegestrant is undergoing Phase 3 trials, showing promising clinical activity and safety in heavily pre-treated breast cancer patients. The company has also initiated a strategic license agreement with Novartis for the global development and commercialization of ARV-766, affirming its potential as a first-in-class treatment for prostate cancer.
Financially, Arvinas maintains a strong position with sufficient resources to fund operations into 2027, bolstered by strategic collaborations and revenue from ongoing license agreements. The company's focus on expanding its clinical trials and exploring new combination therapies positions it for significant impact in oncology and beyond.
For the latest updates on Arvinas' developments and clinical trials, visit their website at www.arvinas.com.
Arvinas, a clinical-stage biotechnology company focused on targeted protein degradation, will have its Chief Scientific Officer Ian Taylor and Chief Financial Officer Sean Cassidy participate in a fireside chat during the Stifel Targeted Oncology Day on April 26, 2023, at 11:30 a.m. ET. The event will be available via a live audio webcast, accessible from Arvinas' website. The company aims to develop therapies that degrade disease-causing proteins and currently has three investigational clinical-stage programs. These programs include bavdegalutamide and ARV-766 for prostate cancer treatment, as well as ARV-471 for breast cancer. The company uses its proprietary PROTAC Discovery Engine to engineer targeted protein degraders.
Arvinas, Inc. (Nasdaq: ARVN) has appointed Kelly Page as Senior Vice President, Global Head of Oncology Strategy and Program Leadership. With over 25 years in the pharmaceutical industry, including significant experience in oncology from her previous role at AstraZeneca, Ms. Page is expected to enhance Arvinas' Executive Committee. Her expertise spans research to commercialization, which may strengthen the company’s focus on developing targeted protein degradation therapeutics. This leadership change aligns with Arvinas' commitment to advancing its clinical-stage oncology programs, including those for prostate and breast cancers.
Arvinas, a clinical-stage biotechnology company focused on targeted protein degradation, will participate in two upcoming investor conferences. The Cowen 43rd Annual Health Care Conference is scheduled for March 6, featuring a fireside chat with Chief Medical Officer Ron Peck and Senior VP Randy Teel. A live audio webcast will be available here. The Oppenheimer 33rd Annual Healthcare Conference will be held on March 13, with the same speakers and similar webcast availability here.
Arvinas, a clinical-stage biotechnology company, reported significant developments in its drug pipeline, specifically ARV-471, for treating ER+/HER2- metastatic breast cancer. The company initiated a Phase 3 trial for this monotherapy and presented Phase 2 data from the VERITAC trial. Arvinas gained FDA alignment for a Phase 3 trial combining ARV-471 with palbociclib, set to start in 2H 2023. Financially, Arvinas recorded revenue of $131.4 million for 2022, up from $53.6 million in 2021, largely due to the ARV-471 collaboration with Pfizer. However, the company also posted a net loss of $282.5 million and research expenses rose to $315 million.
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