Welcome to our dedicated page for Altimmune news (Ticker: ALT), a resource for investors and traders seeking the latest updates and insights on Altimmune stock.
Altimmune, Inc. (Nasdaq: ALT) is a clinical-stage biopharmaceutical company dedicated to developing next-generation immunotherapeutics and vaccines addressing critical public health and biodefense needs. Leveraging the unique properties of its proprietary platform technologies, Altimmune is adept at swiftly designing product candidates targeting a range of diseases, including respiratory conditions, chronic infections, and cancer.
Altimmune's advanced Densigen™ T-cell platform technology is specifically designed to guide the immune system's response against complex disease targets by focusing on multiple antigens simultaneously. Another key platform, RespirVec™, uses needle-free intranasal delivery for faster and broader immunity against pathogens compared to traditional vaccines.
The company is also heavily involved in addressing obesity and liver diseases through its innovative peptide therapeutics. The lead product candidate, pemvidutide, is a GLP-1/glucagon dual receptor agonist under development for obesity and non-alcoholic steatohepatitis (NASH). Pemvidutide has shown promising results in clinical trials, achieving significant weight loss and liver fat reduction. It has received Fast Track designation from the U.S. FDA for treating NASH, highlighting its potential to meet significant unmet medical needs.
Altimmune's pipeline also includes HepTcell™, an immunotherapeutic designed to achieve a functional cure for chronic hepatitis B. However, the company has recently decided to cease further development on HepTcell based on Phase 2 trial findings.
Financially, Altimmune maintains a robust cash position, enabling it to advance its clinical programs. Recent financial results indicate a focused investment in research and development, ensuring continued progress in its pipeline.
Significant recent achievements include:
- Positive top-line results from the 48-week MOMENTUM Phase 2 obesity trial of pemvidutide.
- Ongoing Phase 2b IMPACT trial of pemvidutide in MASH with top-line results expected in Q1 2025.
- Strong financial position with substantial cash reserves to support ongoing and future research activities.
Altimmune is poised at the forefront of developing transformative therapies for serious health conditions, potentially delivering significant advancements in patient care.
Altimmune has submitted an Investigational New Drug (IND) application for its single-dose intranasal COVID-19 vaccine, AdCOVID, to the FDA. AdCOVID aims to stimulate comprehensive immunity, including local nasal mucosal immunity, crucial for preventing virus transmission. The Phase 1 trial is expected to begin in Q4 2020, with data readout anticipated in Q1 2021. The vaccine's advantages include easy administration, room-temperature transport, and potential pediatric use. The FDA has approved the study design and patient population, deeming no additional toxicology studies necessary.
Altimmune, Inc. (Nasdaq: ALT) announced its participation in upcoming virtual investor conferences. These events include the Jefferies London Virtual Healthcare Conference on November 17, 2020, the Piper Sandler 32nd Annual Virtual Healthcare Conference from November 23 to December 3, 2020, and the 3rd Annual Evercore ISI Virtual HealthCONx Conference on December 2, 2020. All sessions will be accessible through the investor relations section of Altimmune's website. The company focuses on developing intranasal vaccines and therapies for diseases, including COVID-19 and liver disease.
Altimmune has announced an agreement with Lonza to manufacture its AdCOVID intranasal vaccine for COVID-19. This partnership aims to enhance Altimmune's commercial readiness for potential vaccine distribution in 2021. The AdCOVID vaccine is designed for easy administration and aims to provide broad immune responses, including mucosal immunity. Preclinical studies indicate a significant increase in mucosal IgA. The company plans to initiate a Phase 1 clinical trial in Q4 2020, with results expected in Q1 2021.
Altimmune, Inc. (Nasdaq: ALT) reported its Q3 2020 financial results, highlighting a revenue increase to $2.9 million from $0.6 million year-over-year, largely driven by U.S. government contracts. The company is advancing several investigational candidates, including AdCOVID, T-COVID, and ALT-801, with plans for clinical trials commencing this year. Research and development expenses rose to $17 million, leading to a net loss of $17.8 million, or $0.54 per share. Altimmune has secured approximately $200 million to support its pipeline initiatives.
Altimmune, Inc. (Nasdaq: ALT) announced it will release its third quarter 2020 financial results on November 10, 2020. A conference call for investors will follow at 8:30 a.m. ET on the same day, where management will discuss the financial results and provide a business update. The company, focused on developing intranasal vaccines and therapies, has a diverse pipeline including products for COVID-19, anthrax, and liver disease. For more details, investors can access the conference call via a webcast.
Altimmune, a clinical-stage biopharmaceutical company (Nasdaq: ALT), announced its participation in two upcoming virtual investor conferences. The first is the H.C. Wainwright Hepatitis B Virus Conference on October 20, 2020, at 1:30 PM EDT, which will be webcast through the company's investor relations page. The second event is the B. Riley Securities Liver Disease Symposium on October 29, 2020. Altimmune specializes in intranasal vaccines and therapies for liver diseases, including COVID-19 and hepatitis B.
Altimmune's AdCOVID, a single-dose intranasal COVID-19 vaccine, shows promising preclinical results. The comprehensive evaluation highlights AdCOVID's ability to stimulate serum neutralizing antibodies, T cell responses, and mucosal immunity in the respiratory tract. In studies with mice, AdCOVID demonstrated a median neutralization titer of 1:563, exceeding FDA's convalescent plasma standard. The company plans to file an IND and begin a Phase 1 trial in Q4 2020. AdCOVID's advantages include easy storage, broad immune activation, and potential for self-administration.
Altimmune, Inc. (Nasdaq: ALT) announced a preclinical data presentation on ALT-801, a GLP-1/glucagon receptor dual agonist, targeting NASH at the Digital International Liver Congress™ 2020. The presentation highlighted ALT-801’s superior efficacy compared to semaglutide in reducing body weight, liver fat, and fibrosis markers in a preclinical mouse model. The company is preparing to start its first human Phase 1 trial in Australia in Q4 2020, with results anticipated in spring 2021.
Altimmune, Inc. (Nasdaq: ALT) reported promising results from preclinical studies of its intranasal COVID-19 vaccine candidate, AdCOVID. The research demonstrated significant stimulation of CD4+ and CD8+ T cell responses in the lungs of mice, with a strong bias towards CD8+ T cells within 10 days post-vaccination. AdCOVID showed a 29-fold increase in mucosal IgA antibodies specific to the spike protein. The company is on track to start a Phase 1 safety and immunogenicity study in Q4 2020. The vaccine's intranasal administration could facilitate rapid distribution without cold-chain logistics.
Altimmune, Inc. (Nasdaq: ALT) announced it will report its financial results for Q2 2020 before the market opens on August 12, 2020, and will host a conference call at 8:30 am ET. The company is focused on developing intranasal vaccines and immune modulating therapies, including those for COVID-19 and liver diseases. Notable products in their pipeline include AdCOVID™, NasoShield™, and ALT-801. Investors can access the conference call via the provided webcast link.
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