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Biocryst Pharmaceuticals Inc Financials

BCRX
Source SEC Filings (10-K/10-Q) Updated Dec 31, 2025 Currency USD FYE December

This page shows Biocryst Pharmaceuticals Inc (BCRX) financial statements, including the income statement, balance sheet, cash flow statement, and key financial ratios. View 17 years of annual fundamentals and quarterly data, with year-over-year growth rates and compound annual growth rates (CAGR). All figures are derived from SEC filings (10-K and 10-Q reports).

Financial Health Signals

Profitability Growth Leverage Liquidity Cash Flow Returns 84 / 100
Financial Profile 84/100

Based on FY2025 annual data. Scores normalized against common benchmarks. How we calculate these scores

Profitability
100

Biocryst Pharmaceuticals Inc has an operating margin of 39.0%, meaning the company retains $39 of operating profit per $100 of revenue. This strong profitability earns a score of 100/100, reflecting efficient cost management and pricing power. This is up from -0.6% the prior year.

Growth
100

Biocryst Pharmaceuticals Inc's revenue surged 94.1% year-over-year to $874.8M, reflecting rapid business expansion. This strong growth earns a score of 100/100.

Liquidity
37

Biocryst Pharmaceuticals Inc's current ratio of 2.06 indicates adequate short-term liquidity, earning a score of 37/100. The company can meet its near-term obligations, though with limited headroom.

Cash Flow
100

Biocryst Pharmaceuticals Inc converts 39.4% of revenue into free cash flow ($344.9M). This strong cash generation earns a score of 100/100.

Altman Z-Score Grey Zone
2.42

Biocryst Pharmaceuticals Inc scores 2.42, placing it in the grey zone between 1.81 and 2.99. The score is driven primarily by a large market capitalization ($2.3B) relative to total liabilities ($633.3M). This signals moderate financial risk that warrants monitoring.

Piotroski F-Score Strong
7/9

Biocryst Pharmaceuticals Inc passes 7 of 9 financial strength tests. All 4 profitability signals pass (positive income, cash flow, and earnings quality), 1 of 3 leverage/liquidity signals pass, both operating efficiency signals pass.

Earnings Quality Cash-Backed
1.32x

For every $1 of reported earnings, Biocryst Pharmaceuticals Inc generates $1.32 in operating cash flow ($347.4M OCF vs $263.9M net income). This indicates profits are well-supported by actual cash generation, not accounting adjustments.

Interest Coverage Adequate
4.3x

Biocryst Pharmaceuticals Inc earns $4.3 in operating income for every $1 of interest expense ($341.0M vs $78.9M). This adequate coverage means the company can meet its interest obligations, but has limited cushion if earnings fall.

Key Financial Metrics

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Earnings & Revenue

Revenue
$874.8M
YoY+94.1%
5Y CAGR+117.9%
10Y CAGR+33.6%

Biocryst Pharmaceuticals Inc generated $874.8M in revenue in fiscal year 2025. This represents an increase of 94.1% from the prior year.

EBITDA
$342.4M
YoY+26497.7%

Biocryst Pharmaceuticals Inc's EBITDA was $342.4M in fiscal year 2025, measuring earnings before interest, taxes, depreciation, and amortization. This represents an increase of 26497.7% from the prior year.

Net Income
$263.9M
YoY+396.9%

Biocryst Pharmaceuticals Inc reported $263.9M in net income in fiscal year 2025. This represents an increase of 396.9% from the prior year.

EPS (Diluted)
$1.21
YoY+381.4%

Biocryst Pharmaceuticals Inc earned $1.21 per diluted share (EPS) in fiscal year 2025. This represents an increase of 381.4% from the prior year.

Cash & Balance Sheet

Free Cash Flow
$344.9M
YoY+749.0%

Biocryst Pharmaceuticals Inc generated $344.9M in free cash flow in fiscal year 2025, representing cash available after capex. This represents an increase of 749.0% from the prior year.

Cash & Debt
$89.7M
YoY-14.3%
5Y CAGR-19.9%
10Y CAGR+12.0%

Biocryst Pharmaceuticals Inc held $89.7M in cash against $0 in long-term debt as of fiscal year 2025.

Dividends Per Share
N/A
Shares Outstanding
213M
YoY+2.2%
5Y CAGR+3.8%
10Y CAGR+11.2%

Biocryst Pharmaceuticals Inc had 213M shares outstanding in fiscal year 2025. This represents an increase of 2.2% from the prior year.

Margins & Returns

Gross Margin
97.8%
YoY+0.5pp
5Y CAGR+6.5pp
10Y CAGR+0.6pp

Biocryst Pharmaceuticals Inc's gross margin was 97.8% in fiscal year 2025, indicating the percentage of revenue retained after direct costs. This is up 0.5 percentage points from the prior year.

Operating Margin
39.0%
YoY+39.5pp
5Y CAGR+1020.1pp
10Y CAGR+120.7pp

Biocryst Pharmaceuticals Inc's operating margin was 39.0% in fiscal year 2025, reflecting core business profitability. This is up 39.5 percentage points from the prior year.

Net Margin
30.2%
YoY+49.9pp
5Y CAGR+1056.5pp
10Y CAGR+119.3pp

Biocryst Pharmaceuticals Inc's net profit margin was 30.2% in fiscal year 2025, showing the share of revenue converted to profit. This is up 49.9 percentage points from the prior year.

Return on Equity
N/A

Capital Allocation

R&D Spending
$166.1M
YoY-4.9%
5Y CAGR+6.2%
10Y CAGR+8.6%

Biocryst Pharmaceuticals Inc invested $166.1M in research and development in fiscal year 2025. This represents a decrease of 4.9% from the prior year.

Share Buybacks
N/A
Capital Expenditures
$2.5M
YoY+119.6%
5Y CAGR+36.9%
10Y CAGR-7.0%

Biocryst Pharmaceuticals Inc invested $2.5M in capex in fiscal year 2025, funding long-term assets and infrastructure. This represents an increase of 119.6% from the prior year.

BCRX Income Statement

Metric Q4'25 Q3'25 Q2'25 Q1'25 Q4'24 Q3'24 Q2'24 Q1'24
Revenue $406.6M+155.1% $159.4M-2.4% $163.4M+12.2% $145.5M+10.6% $131.5M+12.3% $117.1M+7.1% $109.3M+17.9% $92.8M
Cost of Revenue $9.5M+335.4% $2.2M-21.8% $2.8M-38.7% $4.6M-25.0% $6.1M+89.8% $3.2M+89.0% $1.7M+34.3% $1.3M
Gross Profit $397.0M+152.6% $157.2M-2.1% $160.6M+13.9% $141.0M+12.4% $125.4M+10.2% $113.9M+5.8% $107.6M+17.6% $91.5M
R&D Expenses $40.9M-8.4% $44.6M+2.8% $43.4M+16.4% $37.3M-24.6% $49.4M+20.4% $41.1M+9.2% $37.6M-19.1% $46.5M
SG&A Expenses $95.8M+15.4% $83.0M-5.0% $87.4M+6.0% $82.5M+2.4% $80.5M+23.7% $65.1M+6.3% $61.2M+3.0% $59.5M
Operating Income $260.4M+779.9% $29.6M-0.7% $29.8M+40.3% $21.2M+570.9% -$4.5M-158.6% $7.7M-12.2% $8.8M+160.5% -$14.5M
Interest Expense $14.1M-28.1% $19.7M-8.9% $21.6M-8.1% $23.5M-3.9% $24.4M-1.5% $24.8M+0.4% $24.7M+0.9% $24.5M
Income Tax $2.2M+382.4% -$769K-154.9% $1.4M+93.0% $726K-9.7% $804K+37.2% $586K+240.7% $172K-52.9% $365K
Net Income $245.8M+1805.9% $12.9M+153.7% $5.1M+15790.6% $32K+100.1% -$26.8M-90.9% -$14.0M-10.7% -$12.7M+64.2% -$35.4M
EPS (Diluted) N/A $0.06+200.0% $0.02 $0.00 N/A $-0.07-16.7% $-0.06+64.7% $-0.17

BCRX Balance Sheet

Metric Q4'25 Q3'25 Q2'25 Q1'25 Q4'24 Q3'24 Q2'24 Q1'24
Total Assets $514.2M+15.2% $446.4M-2.4% $457.2M-4.8% $480.0M-2.1% $490.4M-0.2% $491.3M+4.0% $472.4M+1.0% $467.9M
Current Assets $404.3M+13.7% $355.7M-10.7% $398.5M-2.8% $410.0M-2.8% $422.0M-1.2% $427.1M+17.5% $363.5M-18.7% $447.1M
Cash & Equivalents $89.7M+6.7% $84.1M-4.5% $88.0M-16.3% $105.2M+0.5% $104.7M+8.1% $96.8M+23.5% $78.4M-7.0% $84.3M
Inventory $5.4M+3.2% $5.2M+3.7% $5.0M-26.6% $6.9M-15.0% $8.1M+6.9% $7.6M+69.9% $4.5M-85.1% $29.8M
Accounts Receivable $106.8M+17.0% $91.3M+0.2% $91.2M-2.4% $93.4M+18.1% $79.1M+9.1% $72.5M+5.4% $68.8M+13.5% $60.6M
Goodwill N/A N/A N/A N/A N/A N/A N/A N/A
Total Liabilities $633.3M-24.1% $834.3M-5.1% $878.8M-5.7% $932.0M-3.6% $966.4M+0.7% $959.8M+1.2% $948.0M+0.4% $944.1M
Current Liabilities $196.1M+3.1% $190.2M+7.4% $177.2M+26.7% $139.9M-12.8% $160.4M+4.4% $153.6M+19.0% $129.1M+7.6% $119.9M
Long-Term Debt $0-100.0% $194.4M-19.9% $242.8M-23.0% $315.4M+0.2% $314.9M+0.2% $314.3M+0.2% $313.8M+1.7% $308.5M
Total Equity -$119.2M+69.3% -$387.9M+8.0% -$421.6M+6.7% -$451.9M+5.0% -$475.9M-1.6% -$468.6M+1.5% -$475.6M+0.1% -$476.2M
Retained Earnings -$1.5B+14.0% -$1.8B+0.7% -$1.8B+0.3% -$1.8B0.0% -$1.8B-1.5% -$1.7B-0.8% -$1.7B-0.7% -$1.7B

BCRX Cash Flow Statement

Metric Q4'25 Q3'25 Q2'25 Q1'25 Q4'24 Q3'24 Q2'24 Q1'24
Operating Cash Flow $292.0M+601.4% $41.6M+0.8% $41.3M+250.1% -$27.5M-427.9% -$5.2M-163.2% $8.2M+702.7% -$1.4M+97.5% -$53.7M
Capital Expenditures $802K-40.3% $1.3M+650.8% $179K+25.2% $143K-78.8% $675K+1044.1% $59K-61.9% $155K-34.0% $235K
Free Cash Flow $291.2M+622.8% $40.3M-2.0% $41.1M+248.7% -$27.7M-369.8% -$5.9M-171.9% $8.2M+637.5% -$1.5M+97.2% -$53.9M
Investing Cash Flow -$83.5M-715.1% $13.6M-53.4% $29.1M+7.5% $27.1M+52.2% $17.8M+109.6% $8.5M+446.6% -$2.4M-108.5% $28.8M
Financing Cash Flow -$218.0M-270.6% -$58.8M+20.2% -$73.7M-14029.3% $529K+113.2% -$4.0M-415.6% $1.3M+164.8% -$2.0M-87.6% -$1.0M
Dividends Paid N/A N/A N/A N/A N/A N/A N/A N/A
Share Buybacks N/A N/A N/A N/A N/A N/A N/A N/A

BCRX Financial Ratios

Metric Q4'25 Q3'25 Q2'25 Q1'25 Q4'24 Q3'24 Q2'24 Q1'24
Gross Margin 97.7%-1.0pp 98.6%+0.3pp 98.3%+1.4pp 96.9%+1.5pp 95.4%-1.9pp 97.3%-1.2pp 98.5%-0.2pp 98.6%
Operating Margin 64.0%+45.5pp 18.6%+0.3pp 18.2%+3.6pp 14.6%+18.0pp -3.4%-10.0pp 6.6%-1.4pp 8.0%+23.6pp -15.6%
Net Margin 60.5%+52.4pp 8.1%+5.0pp 3.1%+3.1pp 0.0%+20.4pp -20.4%-8.4pp -12.0%-0.4pp -11.6%+26.6pp -38.1%
Return on Equity N/A N/A N/A N/A N/A N/A N/A N/A
Return on Assets 47.8%+44.9pp 2.9%+1.8pp 1.1%+1.1pp 0.0%+5.5pp -5.5%-2.6pp -2.9%-0.2pp -2.7%+4.9pp -7.6%
Current Ratio 2.06+0.2 1.87-0.4 2.25-0.7 2.93+0.3 2.63-0.2 2.78-0.0 2.82-0.9 3.73
Debt-to-Equity 0.00+0.5 -0.50+0.1 -0.58+0.1 -0.70-0.0 -0.660.0 -0.67-0.0 -0.66-0.0 -0.65
FCF Margin 71.6%+46.3pp 25.3%+0.1pp 25.2%+44.2pp -19.0%-14.5pp -4.5%-11.5pp 7.0%+8.4pp -1.4%+56.7pp -58.1%

Note: Shareholder equity is negative (-$119.2M), which causes debt-to-equity and return on equity ratios to appear negative or not meaningful. This can occur from accumulated losses or large share buyback programs.

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Frequently Asked Questions

Biocryst Pharmaceuticals Inc (BCRX) reported $874.8M in total revenue for fiscal year 2025. This represents a 94.1% change compared to the previous fiscal year. Revenue measures the total income earned from the company's primary business operations before any expenses are deducted.

Biocryst Pharmaceuticals Inc (BCRX) revenue grew by 94.1% year-over-year, from $450.7M to $874.8M in fiscal year 2025.

Yes, Biocryst Pharmaceuticals Inc (BCRX) reported a net income of $263.9M in fiscal year 2025, with a net profit margin of 30.2%.

Biocryst Pharmaceuticals Inc (BCRX) reported diluted earnings per share of $1.21 for fiscal year 2025. This represents a 381.4% change compared to the previous fiscal year. EPS represents the portion of a company's net income allocated to each outstanding share of common stock and is widely used to evaluate profitability on a per-share basis.

Biocryst Pharmaceuticals Inc (BCRX) had EBITDA of $342.4M in fiscal year 2025, measuring earnings before interest, taxes, depreciation, and amortization.

As of fiscal year 2025, Biocryst Pharmaceuticals Inc (BCRX) had $89.7M in cash and equivalents against $0 in long-term debt.

Biocryst Pharmaceuticals Inc (BCRX) had a gross margin of 97.8% in fiscal year 2025, indicating the percentage of revenue retained after direct costs of goods sold.

Biocryst Pharmaceuticals Inc (BCRX) had an operating margin of 39.0% in fiscal year 2025, reflecting the profitability of core business operations before interest and taxes.

Biocryst Pharmaceuticals Inc (BCRX) had a net profit margin of 30.2% in fiscal year 2025, representing the share of revenue converted into profit after all expenses.

Biocryst Pharmaceuticals Inc (BCRX) generated $344.9M in free cash flow during fiscal year 2025. This represents a 749.0% change compared to the previous fiscal year. Free cash flow represents the cash a company generates after accounting for capital expenditures, and is widely used to assess financial flexibility and shareholder value.

Biocryst Pharmaceuticals Inc (BCRX) generated $347.4M in operating cash flow during fiscal year 2025, representing cash generated from core business activities.

Biocryst Pharmaceuticals Inc (BCRX) had $514.2M in total assets as of fiscal year 2025, including both current and long-term assets.

Biocryst Pharmaceuticals Inc (BCRX) invested $2.5M in capital expenditures during fiscal year 2025, funding long-term assets and infrastructure.

Biocryst Pharmaceuticals Inc (BCRX) invested $166.1M in research and development during fiscal year 2025.

Biocryst Pharmaceuticals Inc (BCRX) had 213M shares outstanding as of fiscal year 2025.

Biocryst Pharmaceuticals Inc (BCRX) had a current ratio of 2.06 as of fiscal year 2025, which is generally considered healthy.

Biocryst Pharmaceuticals Inc (BCRX) had a debt-to-equity ratio of 0.00 as of fiscal year 2025, measuring the company's financial leverage by comparing total debt to shareholder equity.

Biocryst Pharmaceuticals Inc (BCRX) had a return on assets of 51.3% for fiscal year 2025, measuring how efficiently the company uses its assets to generate profit.

Biocryst Pharmaceuticals Inc (BCRX) has negative shareholder equity of -$119.2M as of fiscal year 2025, which causes the debt-to-equity ratio to appear negative or not meaningful. This can occur when accumulated losses exceed invested capital, or after large share buyback programs. Other solvency metrics like the current ratio or interest coverage may be more informative.

Biocryst Pharmaceuticals Inc (BCRX) has an Altman Z-Score of 2.42, placing it in the Grey Zone (moderate risk). The Z-Score combines five financial ratios—working capital, retained earnings, EBIT, market capitalization, and revenue relative to total assets—to predict the likelihood of bankruptcy. Scores above 2.99 indicate financial safety while scores below 1.81 suggest financial distress. Learn more in our complete guide to financial health indicators.

Biocryst Pharmaceuticals Inc (BCRX) has a Piotroski F-Score of 7 out of 9, indicating strong financial health. The F-Score evaluates nine binary signals across profitability (positive ROA, positive cash flow, improving ROA, earnings quality), leverage (decreasing debt, improving liquidity, no share dilution), and operating efficiency (improving gross margin, improving asset turnover). Scores of 7–9 indicate strong and improving fundamentals. Learn more in our complete guide to financial health indicators.

Biocryst Pharmaceuticals Inc (BCRX) has an earnings quality ratio of 1.32x, considered cash-backed (high quality). This ratio compares operating cash flow to net income. A ratio above 1.0x means the company generates more cash than its reported earnings, indicating sustainable, cash-backed profits. Ratios below 1.0x suggest earnings rely on accounting accruals rather than actual cash generation. Learn more in our complete guide to financial health indicators.

Biocryst Pharmaceuticals Inc (BCRX) has an interest coverage ratio of 4.3x, meaning it can adequately cover its interest obligations. This ratio divides operating income by interest expense. Ratios above 5x indicate strong debt-servicing ability, while ratios below 2x suggest the company may face difficulty meeting interest payments if earnings decline. Learn more in our complete guide to financial health indicators.

Biocryst Pharmaceuticals Inc (BCRX) scores 84 out of 100 on our Financial Profile, indicating strong overall financial health. This composite score evaluates six dimensions: profitability (operating margin), revenue growth, leverage (debt-to-equity), liquidity (current ratio), cash flow quality (free cash flow margin), and shareholder returns (return on equity). Each dimension is normalized against standard financial benchmarks. Learn more in our complete guide to financial health indicators.

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