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Sofinnova Venture Partners XI converts preferred into 2.7M Seaport Therapeutics (SPTX) shares

Filing Impact
(Neutral)
Filing Sentiment
(Neutral)
Form Type
4

Rhea-AI Filing Summary

Seaport Therapeutics, Inc. reported that investment fund Sofinnova Venture Partners XI, L.P. converted its preferred stock into common shares in connection with the closing of the company’s initial public offering. The transactions are attributed to Sofinnova, not directly to director James Healy, who is a managing member of the fund’s general partner and disclaims beneficial ownership except for any pecuniary interest.

Sofinnova converted 2,526,315 shares of Series B Preferred Stock into 804,379 shares of common stock and 6,052,631 shares of Series A-2 Preferred Stock into 1,927,159 shares of common stock, based on a one-for-3.1407 conversion ratio. Following these conversions, Sofinnova directly holds 2,731,538 common shares of Seaport Therapeutics.

Positive

  • None.

Negative

  • None.
Insider HEALY JAMES
Role null
Type Security Shares Price Value
Conversion Series A-2 Preferred Stock 6,052,631 $0.00 --
Conversion Series B Preferred Stock 2,526,315 $0.00 --
Conversion Common Stock 1,927,159 $0.00 --
Conversion Common Stock 804,379 $0.00 --
Holdings After Transaction: Series A-2 Preferred Stock — 0 shares (Indirect, By Sofinnova Venture Partners XI, L.P.); Series B Preferred Stock — 0 shares (Indirect, By Sofinnova Venture Partners XI, L.P.); Common Stock — 1,927,159 shares (Indirect, By Sofinnova Venture Partners XI, L.P.)
Footnotes (1)
  1. Each share of Series A-2 and Series B Preferred Stock (collectively, the "Preferred Stock") was convertible into Common Stock of the Issuer on a one-for-3.1407 basis at the option of the holder, and automatically converted upon the closing of the Issuer's initial public offering without payment of further consideration. The Preferred Stock had no expiration date. These shares are directly held by Sofinnova Venture Partners XI, L.P. ("SVP XI"). Sofinnova Management XI, L.P. ("SM XI LP") is the general partner of SVP XI, and Sofinnova Management XI, L.L.C. ("SM XI") is the general partner of SM XI LP. The Reporting Person is a managing member of SM XI and may be deemed to share voting and investment discretion with respect to securities directly held by SVP XI. The Reporting Person disclaims beneficial ownership of the securities directly held by SVP XI. This report shall not be construed as an admission that he is the beneficial owner of the securities reported herein for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or for any other purpose, except to the extent of his pecuniary interest therein, if any.
Series B Preferred converted 2,526,315 shares Converted into 804,379 common shares on May 4, 2026
Series A-2 Preferred converted 6,052,631 shares Converted into 1,927,159 common shares on May 4, 2026
Common from Series B 804,379 shares Common stock received by Sofinnova from Series B conversion
Common from Series A-2 1,927,159 shares Common stock received by Sofinnova from Series A-2 conversion
Common shares held after 2,731,538 shares Sofinnova common stock position following conversions
Conversion ratio 1 share per 3.1407 preferred Series A-2 and Series B Preferred into common stock
Series A-2 Preferred Stock financial
"Each share of Series A-2 and Series B Preferred Stock was convertible into Common Stock"
Series A-2 preferred stock is a specific class of shares created during a funding round that gives its holders stronger financial protections and priority over common shareholders, such as getting paid first if the company is sold or winding down. Investors care because these shares behave like a hybrid between a loan and regular stock: they often offer fixed payouts or conversion rights and a better claim on assets, making them lower risk and shaping potential returns.
Series B Preferred Stock financial
"Each share of Series A-2 and Series B Preferred Stock was convertible into Common Stock"
Series B preferred stock is a type of ownership share issued by a company that offers certain advantages over common stock, such as priority in receiving dividends or assets if the company is sold or liquidated. It is typically issued after an initial round of funding, making it a way for investors to support a company's growth while gaining some protections and benefits. This stock matters to investors because it often provides a more secure investment position with potential for future growth.
conversion of derivative security financial
"transaction code "C" is described as Conversion of derivative security"
initial public offering financial
"automatically converted upon the closing of the Issuer's initial public offering"
An initial public offering (IPO) is when a private company first sells its shares to the public and becomes a stock-listed company. It matters because it allows the company to raise money from a wide range of investors, helping it grow, while giving early shareholders a way to sell some of their ownership.
pecuniary interest financial
"except to the extent of his pecuniary interest therein, if any"
SEC Form 4
FORM 4UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940
OMB APPROVAL
OMB Number:3235-0287
Estimated average burden
hours per response:0.5
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.
1. Name and Address of Reporting Person*
HEALY JAMES

(Last)(First)(Middle)
SEAPORT THERAPEUTICS, INC.
101 SEAPORT BLVD., FLOOR 12

(Street)
BOSTON MASSACHUSETTS 02210

(City)(State)(Zip)

UNITED STATES

(Country)
2. Issuer Name and Ticker or Trading Symbol
Seaport Therapeutics, Inc. [ SPTX ]
5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
XDirector10% Owner
Officer (give title below)Other (specify below)
2a. Foreign Trading Symbol
3. Date of Earliest Transaction (Month/Day/Year)
05/04/2026
6. Individual or Joint/Group Filing (Check Applicable Line)
XForm filed by One Reporting Person
Form filed by More than One Reporting Person
4. If Amendment, Date of Original Filed (Month/Day/Year)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3) 2. Transaction Date (Month/Day/Year)2A. Deemed Execution Date, if any (Month/Day/Year)3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
CodeVAmount(A) or (D)Price
Common Stock05/04/2026C1,927,159A(1)1,927,159IBy Sofinnova Venture Partners XI, L.P.(2)
Common Stock05/04/2026C804,379A(1)2,731,538IBy Sofinnova Venture Partners XI, L.P.(2)
Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year)3A. Deemed Execution Date, if any (Month/Day/Year)4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 6. Date Exercisable and Expiration Date (Month/Day/Year)7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4)
CodeV(A)(D)Date ExercisableExpiration DateTitleAmount or Number of Shares
Series A-2 Preferred Stock(1)05/04/2026C6,052,631 (1) (1)Common Stock1,927,159$00IBy Sofinnova Venture Partners XI, L.P.(2)
Series B Preferred Stock(1)05/04/2026C2,526,315 (1) (1)Common Stock804,379$00IBy Sofinnova Venture Partners XI, L.P.(2)
Explanation of Responses:
1. Each share of Series A-2 and Series B Preferred Stock (collectively, the "Preferred Stock") was convertible into Common Stock of the Issuer on a one-for-3.1407 basis at the option of the holder, and automatically converted upon the closing of the Issuer's initial public offering without payment of further consideration. The Preferred Stock had no expiration date.
2. These shares are directly held by Sofinnova Venture Partners XI, L.P. ("SVP XI"). Sofinnova Management XI, L.P. ("SM XI LP") is the general partner of SVP XI, and Sofinnova Management XI, L.L.C. ("SM XI") is the general partner of SM XI LP. The Reporting Person is a managing member of SM XI and may be deemed to share voting and investment discretion with respect to securities directly held by SVP XI. The Reporting Person disclaims beneficial ownership of the securities directly held by SVP XI. This report shall not be construed as an admission that he is the beneficial owner of the securities reported herein for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or for any other purpose, except to the extent of his pecuniary interest therein, if any.
/s/ Lana Gladstein, Attorney-in-Fact05/04/2026
** Signature of Reporting PersonDate
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.
* Form 4: SEC 1474 (03-26)

FAQ

What did the Seaport Therapeutics (SPTX) Form 4 filed for James Healy report?

The Form 4 reports that Sofinnova Venture Partners XI, L.P. converted its preferred stock into Seaport Therapeutics common shares upon the company’s IPO closing. These are derivative conversions, not open-market stock purchases or sales by James Healy personally.

How many Seaport Therapeutics (SPTX) common shares did Sofinnova receive in the conversions?

Sofinnova Venture Partners XI received 804,379 common shares from Series B Preferred Stock and 1,927,159 common shares from Series A-2 Preferred Stock. In total, the fund holds 2,731,538 Seaport Therapeutics common shares after these conversions.

Which securities were converted into Seaport Therapeutics (SPTX) common stock?

The filing shows conversions of Series B Preferred Stock and Series A-2 Preferred Stock into common stock. Each share of these preferred series converted into common stock on a one-for-3.1407 basis upon the closing of Seaport Therapeutics’ initial public offering.

Are the Seaport Therapeutics (SPTX) Form 4 transactions open-market buys or sells?

No, the transactions are coded “C” for conversion of derivative securities. They reflect automatic or optional conversions of preferred stock into common stock at IPO closing, rather than discretionary open-market purchases or sales of Seaport Therapeutics common shares.

Who actually holds the Seaport Therapeutics (SPTX) shares reported for James Healy?

The shares are directly held by Sofinnova Venture Partners XI, L.P. James Healy is a managing member of the fund’s general partner and may share voting and investment discretion, but he disclaims beneficial ownership except for any pecuniary interest.

What was the conversion ratio for Seaport Therapeutics (SPTX) preferred stock into common stock?

Each share of Series A-2 and Series B Preferred Stock converted into Seaport Therapeutics common stock on a one-for-3.1407 basis. The preferred shares automatically converted upon the closing of the company’s initial public offering without any additional consideration.