Tax-driven SOPHiA GENETICS (SOPH) insider sale under Rule 10b5-1 plan

Rhea-AI Filing Summary

SOPHiA GENETICS SA President Ross Muken sold 760 Ordinary Shares in an open-market transaction. The shares were sold at a weighted average price of $5.2039 per share to cover tax withholding obligations from restricted stock units that vested on April 18, 2026.

The filing states these sales were made under a pre-established Rule 10b5-1(c) trading plan and are not discretionary trades. After this tax-related sale, Muken directly holds 681,672 Ordinary Shares, indicating the transaction is small relative to his reported position.

Insider Trade Summary 10b5-1

Net Seller: 760 shares ($3,955)

Net Sell 1 txn

Insider Muken Ross

Role President

Sold 760 shs ($4K)

Type	Security	Shares	Price	Value
Sale	Ordinary Shares	760	$5.2039	$4K

Holdings After Transaction: Ordinary Shares — 681,672 shares (Direct, null)

Footnotes (1)

1. Represents shares sold by the Reporting Person in the open market to satisfy tax withholding obligations arising in connection with the vesting of restricted stock units on April 18, 2026. These sales were effected pursuant to a pre-established Rule 10b5-1(c) trading plan adopted by the Reporting Person and do not represent discretionary trades. The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $5.10 to $5.29, inclusive. The Reporting Person undertakes to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon written request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

Key Figures

Shares sold: 760 shares Weighted average sale price: $5.2039 per share Post-transaction holdings: 681,672 shares +2 more

5 metrics

Shares sold 760 shares Open-market sale on April 20, 2026

Weighted average sale price $5.2039 per share Ordinary Shares sold to cover tax withholding

Post-transaction holdings 681,672 shares Ordinary Shares held directly after sale

Price range of sales $5.10–$5.29 per share Multiple transactions within this range

RSU vesting date April 18, 2026 Tax withholding obligations triggered by RSU vesting

Key Terms

restricted stock units, Rule 10b5-1(c) trading plan, weighted average price, open market, +1 more

5 terms

restricted stock units financial

"tax withholding obligations arising in connection with the vesting of restricted stock units on April 18, 2026"

Restricted stock units are a type of company reward where employees are promised shares of stock, but they only fully own these shares after meeting certain conditions, like staying with the company for a set time. They matter because they can become valuable assets and are often used to motivate employees to help the company succeed.

Rule 10b5-1(c) trading plan regulatory

"These sales were effected pursuant to a pre-established Rule 10b5-1(c) trading plan adopted by the Reporting Person"

A Rule 10b5-1(c) trading plan is a legally defined, pre-set schedule that lets company insiders automatically buy or sell stock at specified times or under set formulas when they are not in possession of undisclosed, sensitive information. Think of it like an automatic payment plan for trades: because the instructions are written in advance, trades under the plan help protect insiders from allegations of trading on secret information and give investors clearer expectations about when insiders will transact, which can affect liquidity and perceived transparency.

weighted average price financial

"The price reported in Column 4 is a weighted average price."

Weighted average price is the average price of a security where each trade or component is counted according to its size, so bigger trades pull the average more than smaller ones. Think of it like calculating the average cost of a grocery haul where items you bought more of have greater influence on the final per-item cost. Investors use it to understand the true average price paid or received, judge execution quality, and compare trading performance against market movement.

open market financial

"Represents shares sold by the Reporting Person in the open market to satisfy tax withholding obligations"

An open market is a system where buying and selling of goods, services, or financial assets happen freely without restrictions or special controls. For investors, it means they can trade assets easily and quickly, which helps determine fair prices based on supply and demand. This environment encourages transparency and competition, making it easier to buy or sell with confidence.

tax withholding obligations financial

"to satisfy tax withholding obligations arising in connection with the vesting of restricted stock units"

Form 4 Insider Transactions: What Each Field Means →

SEC Form 4

FORM 4

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940

OMB APPROVAL

OMB Number:			3235-0287
Estimated average burden
hours per response:			0.5

Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

X

Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.

1. Name and Address of Reporting Person^*

Muken Ross

(Last) (First) (Middle)

C/O SOPHIA GENETICS INC.

401 PARK DRIVE, FLOOR 5

(Street)

BOSTON MASSACHUSETTS 02215

(City) (State) (Zip)

UNITED STATES

(Country)

2. Issuer Name and Ticker or Trading Symbol
SOPHiA GENETICS SA [ SOPH ]

5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)

	Director		10% Owner
X	Officer (give title below)		Other (specify below)
	President

2a. Foreign Trading Symbol

3. Date of Earliest Transaction (Month/Day/Year)
04/20/2026

6. Individual or Joint/Group Filing (Check Applicable Line)

X	Form filed by One Reporting Person
	Form filed by More than One Reporting Person

4. If Amendment, Date of Original Filed (Month/Day/Year)

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any (Month/Day/Year)	3. Transaction Code (Instr. 8)		4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5)			5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4)	6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
			Code	V	Amount	(A) or (D)	Price
Ordinary Shares	04/20/2026		S		760(1)	D	$5.2039(2)	681,672	D

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	4. Transaction Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date (Month/Day/Year)		7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
				Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares

Explanation of Responses:

1. Represents shares sold by the Reporting Person in the open market to satisfy tax withholding obligations arising in connection with the vesting of restricted stock units on April 18, 2026. These sales were effected pursuant to a pre-established Rule 10b5-1(c) trading plan adopted by the Reporting Person and do not represent discretionary trades.

2. The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $5.10 to $5.29, inclusive. The Reporting Person undertakes to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon written request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote.

Remarks:

	/s/ Elimara Brunetto as Attorney-in-fact for Ross Muken	04/21/2026
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.
* Form 4: SEC 1474 (03-26)

FAQ

What insider transaction did SOPH President Ross Muken report?

Ross Muken reported selling 760 Ordinary Shares of SOPHiA GENETICS SA in an open-market transaction. The sale was tied to tax withholding obligations from restricted stock units that vested on April 18, 2026, rather than a discretionary stock trade.

At what price did Ross Muken sell SOPH shares in this Form 4?

He sold 760 Ordinary Shares at a weighted average price of $5.2039 per share. The footnote explains shares were sold in multiple trades between $5.10 and $5.29, with detailed trade data available on written request.

Why did Ross Muken sell SOPH shares according to the Form 4?

The sale was made to satisfy tax withholding obligations arising from the vesting of restricted stock units on April 18, 2026. This indicates a mechanically driven transaction linked to compensation, rather than a discretionary decision to reduce his equity exposure.

How many SOPH shares does Ross Muken hold after this transaction?

After selling 760 Ordinary Shares, Ross Muken directly holds 681,672 Ordinary Shares of SOPHiA GENETICS SA. This shows the reported sale is very small compared with his remaining position, according to the share balance disclosed in the Form 4.

Was the SOPH share sale by Ross Muken under a Rule 10b5-1 plan?

Yes. The filing states the sales were executed under a pre-established Rule 10b5-1(c) trading plan adopted by Ross Muken. It also notes the transactions do not represent discretionary trades, highlighting they followed a preset plan rather than ad hoc decisions.

What trading range is disclosed for Ross Muken’s SOPH share sale?

The Form 4 notes that the weighted average sale price of $5.2039 reflects multiple trades executed between $5.10 and $5.29 per share. The reporting person offers to provide detailed trade counts at each price within this range upon written request.