[6-K] PAINREFORM LTD. Current Report (Foreign Issuer)

Rhea-AI Filing Summary

PainReform Ltd. (PRFX) furnished a Form 6-K noting it issued a press release on November 12, 2025 titled “PainReform’s DeepSolar Advances Development of its AI-Driven Automated Reporting Engine for Solar-Asset Analysis.” The release is attached as Exhibit 99.1 and incorporated by reference. The filing provides the exhibit index and signature by Ehud Geller, Executive Chairman and Interim Chief Executive Officer.

Form 6-K: How Foreign Companies Report to the SEC →

UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

Form 6-K

Report of Foreign Private Issuer

Pursuant to Rule 13a-16 or 15d-16

of the Securities Exchange Act of 1934

For the month of November 2025

Commission File Number: 001-39481

PainReform Ltd.

(Translation of registrant’s name into English)

65 Yigal Alon St., Tel Aviv 6744316

Israel

(Address of principal executive offices)

Indicate by check mark whether the registrant files or will file annual reports under cover Form 20-F or Form 40-F.

Form 20-F ☒       Form 40-F ☐

On November 12, 2025, PainReform Ltd. issued a press release entitled “PainReform’s DeepSolar Advances Development of its AI-Driven Automated Reporting Engine for Solar-Asset Analysis”. A copy of the press release is attached hereto as Exhibit 99.1 and incorporated herein by reference.

Exhibit Index

Exhibit No.		Description
99.1		Press Release dated November 12, 2025.

SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned, thereunto duly authorized.

Date: November 12, 2025	PAINREFORM LTD.
	By:	/s/ Ehud Geller
		Ehud Geller Executive Chairman of the Board and Interim Chief Executive Officer