Welcome to our dedicated page for Larimar Therapeutics SEC filings (Ticker: LRMR), a comprehensive resource for investors and traders seeking official regulatory documents including 10-K annual reports, 10-Q quarterly earnings, 8-K material events, and insider trading forms.
The Larimar Therapeutics, Inc. (NASDAQ: LRMR) SEC filings page on Stock Titan provides access to the company’s regulatory disclosures as filed with the U.S. Securities and Exchange Commission. Larimar is a clinical-stage biotechnology company focused on complex rare diseases, with its lead compound, nomlabofusp, in development as a potential treatment for Friedreich’s ataxia. Its SEC filings offer detailed information on clinical progress, financial condition, capital structure, and key corporate events.
Investors can review Larimar’s current reports on Form 8-K, which the company uses to announce material developments. Recent 8-K filings have covered topics such as positive data from the long-term open-label study of nomlabofusp, FDA safety database recommendations and regulatory timelines for a planned Biologics License Application seeking accelerated approval, quarterly financial results, and updates to investor slide presentations. Other 8-Ks describe capital markets transactions, including an underwritten public offering of common stock and an exchange agreement that created Series A convertible preferred stock with defined conversion and ranking terms.
In addition to 8-Ks, users can access Larimar’s periodic reports (Forms 10-K and 10-Q, when available) for broader discussions of research and development expenses, cash position, and risk factors related to the nomlabofusp program and the company’s rare disease focus. These filings elaborate on how Larimar funds its clinical activities, including proceeds from equity offerings and the intended use of capital for research, development, and pre-commercialization efforts.
Stock Titan enhances these documents with AI-powered summaries that highlight the main points of lengthy filings, helping readers quickly identify disclosures related to nomlabofusp’s clinical data, FDA interactions, safety database requirements, and financing arrangements. Real-time updates from EDGAR ensure that new Larimar filings, such as additional 8-Ks, 10-Qs, or 10-Ks, appear promptly, while Form 4 insider transaction reports can be monitored to see how company insiders are transacting in LRMR shares.
Millennium Management LLC, Millennium Group Management LLC and Israel A. Englander report joint beneficial ownership of 3,625,278 shares of Larimar Therapeutics common stock, representing 3.5% of the class.
The filing is an Amendment No. 2 to a Schedule 13G/A and states the disclosed shares are held by entities subject to voting and investment discretion by the reporting persons. A Joint Filing Agreement dated April 29, 2026 is attached.
Larimar Therapeutics, Inc. is asking stockholders to vote at its virtual 2026 Annual Meeting on May 19, 2026, including a proposal to amend its charter to increase authorized common stock from 115,000,000 to 215,000,000 shares.
Stockholders will also vote on electing three Class III directors through 2029, advisory approvals of executive compensation and its voting frequency, ratifying PricewaterhouseCoopers as auditor for 2026, and a potential adjournment if there are insufficient votes for the share increase. The proxy highlights recent progress for nomlabofusp in Friedreich’s ataxia, including FDA Breakthrough Therapy Designation, alignment under the START pilot program toward a Biologics License Application using skin FXN as a surrogate endpoint, and positive long‑term open‑label data. It also notes two underwritten equity offerings in 2025–2026 raising roughly $65.0 million and $107.6 million in net proceeds, director and executive pay structures with a high proportion of at‑risk, performance‑based compensation, and a largely independent, six‑member staggered board with separate chair and CEO roles.
Larimar Therapeutics, Inc. is soliciting proxies for its 2026 virtual Annual Meeting on May 19, 2026 to vote on director elections, executive compensation advisory items, ratification of PwC as auditor, and a proposal to increase authorized common stock from 115,000,000 to 215,000,000. The record date for voting was March 25, 2026, when 103,882,937 shares of common stock were outstanding.
The Proxy Statement summarizes Board composition, governance practices, director and executive compensation, recent corporate highlights (including FDA Breakthrough Therapy designation for nomlabofusp and two 2025 underwritten offerings raising net proceeds of approximately $65.0 million and $107.6 million), audit fees and recommended votes. The Board recommends approval of all proposals, including the charter amendment to increase authorized shares.
Larimar Therapeutics is a clinical-stage biotech focused on rare diseases, led by nomlabofusp for Friedreich’s ataxia (FA). Nomlabofusp uses a cell-penetrating peptide platform to deliver frataxin into mitochondria, aiming to correct the underlying protein deficiency in FA rather than just symptoms.
The company has completed four clinical studies and is running an open-label trial with daily 50 mg dosing, where roughly 8,000 doses have been given. Nomlabofusp holds multiple U.S. and European regulatory designations, participates in FDA’s START pilot, and has Breakthrough Therapy status. Larimar targets a June 2026 BLA submission for accelerated approval using skin frataxin as a surrogate endpoint, alongside a global Phase 3 confirmatory study.
Safety is a key focus: injection site reactions are the most common adverse events, and anaphylaxis has been identified as a likely drug-related reaction, leading to protocol changes including premedication and modified initial dosing. As of December 31, 2025, cash, cash equivalents and marketable securities were $136.9 million, and a February 2026 equity offering added $107.6 million in net proceeds, which together are expected to fund operations into the second quarter of 2027.
Larimar Therapeutics reported a full-year 2025 net loss of $165.7 million, or $2.27 per common share, compared with a net loss of $80.6 million, or $1.32 per share, in 2024. Fourth quarter 2025 net loss was $62.5 million, or $0.73 per common share.
Research and development spending nearly doubled to $154.2 million in 2025, mainly from higher nomlabofusp manufacturing, clinical, and regulatory costs. The FDA granted Breakthrough Therapy Designation for nomlabofusp in Friedreich’s ataxia, and the company plans a June 2026 BLA submission with a potential U.S. launch in the first half of 2027, if approved. Cash, cash equivalents and marketable securities were $136.9 million at December 31, 2025, and pro forma liquidity of $244.5 million including the February 2026 offering is expected to fund operations into the second quarter of 2027.
Larimar Therapeutics, Inc. provides a detailed update on its nomlabofusp program for Friedreich’s ataxia, highlighting regulatory progress, clinical data and funding. Nomlabofusp holds FDA Breakthrough Therapy, Fast Track, Orphan Drug and Rare Pediatric Disease designations, plus PRIME and other expedited designations in Europe and the UK.
The company plans a Biologics License Application seeking accelerated approval in June 2026, supported by an open-label study and a planned global Phase 3 trial using Upright Stability Score and mFARS as primary endpoints. Open-label data show sustained, dose‑dependent increases in skin frataxin, with 100% of 10 evaluated participants above 50% of healthy volunteer levels at 180 days.
Clinical outcomes over one year numerically improved across multiple measures versus a matched FACOMS natural history cohort. Around 8,000 doses have been administered; most adverse events were injection‑site reactions, though 7 of 39 open‑label participants experienced anaphylaxis that resolved with standard treatment. Pro forma cash and investments of $244.5 million as of December 31, 2025 provide an estimated runway into the second quarter of 2027.
Larimar Therapeutics’ major shareholder group Deerfield has updated its ownership following a February 2026 stock offering. Deerfield-affiliated funds bought additional common shares at $5.00 per share in an underwritten offering on February 27, 2026, using available cash.
After these purchases, Deerfield entities report beneficial ownership of 35,667,474 shares of Larimar common stock, or 34.41% of the company’s 103,590,392 shares outstanding, including those issued in the February 2026 offering. Individual Deerfield funds now hold between roughly 5.99% and 10.25% of the outstanding shares.
Larimar Therapeutics, Inc. reported that investment funds managed by Deerfield entities associated with James E. Flynn made significant open-market purchases of its common stock. On February 27, 2026, Deerfield Private Design Fund III, L.P., Deerfield Private Design Fund IV, L.P., Deerfield Healthcare Innovations Fund, L.P., and Deerfield Partners, L.P. collectively bought 5,000,000 shares of Larimar common stock at $5.00 per share in indirect transactions. Following these purchases, each fund reported updated indirect holdings in Larimar, while the reporting persons collectively disclaimed beneficial ownership beyond any indirect pecuniary interest described in the footnotes.
Larimar Therapeutics, Inc. director Thomas Edward Hamilton bought 100,000 shares of common stock in an underwritten offering at $5.00 per share, which closed on February 27, 2026. Following this open-market purchase, he directly owns 664,798 shares and indirectly holds 159,433 shares through Post Edison, LLC.