Opaleye sells 20K Harrow (NASDAQ: HROW) shares in managed account

Rhea-AI Filing Summary

Harrow, Inc. insider Opaleye Management Inc., a 10% owner, reported an indirect sale of Harrow common stock. On January 6, 2026, a separately managed account for which Opaleye acts as portfolio manager sold 20,000 shares of common stock at a weighted average price of $53.3457 per share. After this transaction, the managed account held 70,000 shares indirectly attributed to Opaleye. Separately, 3,815,000 shares were reported as owned by Opaleye, L.P., for which Opaleye Management Inc. is the investment manager. Opaleye Management Inc. states it may be deemed a beneficial owner through these roles but disclaims beneficial ownership beyond its pecuniary interest.

Insights

Insider trading analyst

Opaleye-linked account sold 20,000 Harrow shares, while large indirect holdings remain disclosed.

Opaleye Management Inc., identified as a 10% owner of Harrow, Inc., reported an indirect open-market sale coded "S" of 20,000 shares of common stock on January 6, 2026. The weighted average sale price was $53.3457 per share, with underlying trades occurring between $53.00 and $53.93 inclusive.

Following the sale, the separately managed account for which Opaleye acts as portfolio manager held 70,000 Harrow shares indirectly attributed to it. An additional 3,815,000 shares were reported as owned directly by Opaleye, L.P., where Opaleye Management Inc. serves as investment manager. The filing states Opaleye Management Inc. may be deemed to beneficially own these shares through its roles but explicitly disclaims beneficial ownership except to the extent of its pecuniary interest.

The overall disclosure highlights that a relatively small block was sold compared with the much larger indirect position reported through Opaleye, L.P. and the managed account. Actual economic exposure depends on Opaleye Management Inc.’s pecuniary interest in these entities as described in the footnotes.

Insider Trade Summary

Net Seller: 20,000 shares ($1,066,914)

Net Sell 2 txns

Insider Opaleye Management Inc.

Role 10% Owner

Sold 20,000 shs ($1.07M)

Type	Security	Shares	Price	Value
Sale	Common Stock, par value $0.001 per share	20,000	$53.3457	$1.07M
holding	Common Stock, par value $0.001 per share	--	--	--

Holdings After Transaction: Common Stock, par value $0.001 per share — 70,000 shares (Indirect, By Managed Account)

Footnotes (1)

1. Securities owned by a separately managed account (the "Managed Account"). As the portfolio manager of the Managed Account, Opaleye may be deemed to beneficially own the securities owned directly by the Managed Account. Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund. The price reported in column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $53.00 - $53.93 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares purchased at each price. Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose.

Form 4 Insider Transactions: What Each Field Means →

SEC Form 4

FORM 4

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940

OMB APPROVAL

OMB Number:			3235-0287
Estimated average burden
hours per response:			0.5

Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.

1. Name and Address of Reporting Person^*

Opaleye Management Inc.

(Last) (First) (Middle)

ONE BOSTON PLACE, 26TH FLOOR

(Street)

BOSTON MA 02108

(City) (State) (Zip)

2. Issuer Name and Ticker or Trading Symbol
HARROW, INC. [ HROW ]

5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)

	Director	X	10% Owner
	Officer (give title below)		Other (specify below)

3. Date of Earliest Transaction (Month/Day/Year)
01/06/2026

4. If Amendment, Date of Original Filed (Month/Day/Year)

6. Individual or Joint/Group Filing (Check Applicable Line)

X	Form filed by One Reporting Person
	Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any (Month/Day/Year)	3. Transaction Code (Instr. 8)		4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5)			5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4)	6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
			Code	V	Amount	(A) or (D)	Price
Common Stock, par value $0.001 per share	01/06/2026		S		20,000	D	$53.3457	70,000	I	By Managed Account(1)(3)(4)
Common Stock, par value $0.001 per share								3,815,000	I	By Opaleye, L.P.(2)(4)

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	4. Transaction Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date (Month/Day/Year)		7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
				Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares

Explanation of Responses:

1. Securities owned by a separately managed account (the "Managed Account"). As the portfolio manager of the Managed Account, Opaleye may be deemed to beneficially own the securities owned directly by the Managed Account.

2. Represents securities owned directly by Opaleye, L.P. (the "Fund"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund.

3. The price reported in column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $53.00 - $53.93 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares purchased at each price.

4. Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose.

	Opaleye Management Inc., By: /s/ James Silverman, President	01/08/2026
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.

FAQ

What insider transaction did Opaleye Management Inc. report for Harrow (HROW)?

Opaleye Management Inc., a 10% owner of Harrow, Inc., reported an indirect sale of 20,000 shares of Harrow common stock coded "S" on January 6, 2026.

At what price were the 20,000 Harrow shares sold by the Opaleye-managed account?

The 20,000 shares were sold at a weighted average price of $53.3457 per share, with individual trades executed between $53.00 and $53.93 inclusive.

How many Harrow (HROW) shares did the Opaleye-managed account hold after the reported sale?

After the reported transaction, the separately managed account associated with Opaleye Management Inc. held 70,000 shares of Harrow common stock indirectly attributed to Opaleye.

What larger Harrow share position is reported through Opaleye, L.P.?

The filing reports that Opaleye, L.P. held 3,815,000 shares of Harrow common stock, with Opaleye Management Inc. serving as investment manager and thus potentially deemed a beneficial owner.

Does Opaleye Management Inc. claim full beneficial ownership of the reported Harrow shares?

No. The filing states that Opaleye Management Inc. disclaims beneficial ownership of the reported shares except to the extent of its pecuniary interest in the managed account and the fund.

How is Opaleye Management Inc. related to Harrow, Inc. (HROW)?

Opaleye Management Inc. is reported as a 10% owner of Harrow, Inc. and acts as portfolio manager for a separately managed account and investment manager for Opaleye, L.P., which together hold Harrow shares.