STOCK TITAN

Castle Biosciences (CSTL) CEO reports stock sales under 10b5-1 plan

Filing Impact
(Very High)
Filing Sentiment
(Negative)
Form Type
4

Rhea-AI Filing Summary

Castle Biosciences Inc. reported insider stock sales by its president, chief executive officer and director. On 12/15/2025, the reporting person sold 18,513 shares of common stock at a weighted-average price of $38.747 and 1,012 shares at $39.304. On 12/16/2025, they sold an additional 12,821 shares at a weighted-average price of $38.554. These trades were made under a Rule 10b5-1 trading plan adopted on May 8, 2025. After the reported sales, the reporting person directly owns 34,869 shares of common stock and also has indirect beneficial ownership of multiple blocks of shares through several family and grantor retained annuity trusts.

Positive

  • None.

Negative

  • None.
Insider MAETZOLD DEREK J
Role Pres. & Chief Exec. Officer
Sold 32,346 shs ($1.25M)
Type Security Shares Price Value
Sale Common Stock 12,821 $38.554 $494K
Sale Common Stock 18,513 $38.747 $717K
Sale Common Stock 1,012 $39.304 $40K
holding Common Stock -- -- --
holding Common Stock -- -- --
holding Common Stock -- -- --
holding Common Stock -- -- --
holding Common Stock -- -- --
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holding Common Stock -- -- --
Holdings After Transaction: Common Stock — 34,869 shares (Direct); Common Stock — 52,923 shares (Indirect, By The Maetzold Descendants 2020 Trust)
Footnotes (1)
  1. These transactions were made pursuant to a Rule 10b5-1 plan adopted by the Reporting Person on May 8, 2025. This transaction was executed in multiple trades at prices ranging from $38.240 to $39.220, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. This transaction was executed in multiple trades at prices ranging from $39.240 to $39.390, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. This transaction was executed in multiple trades at prices ranging from $38.135 to $39.070, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected. Held by The Maetzold Descendants 2020 Trust of which the Reporting Person's spouse is the trustee and the Reporting Person's spouse and their children are beneficiaries. Held by Derek Maetzold 2020 Irrevocable Trust of which the Reporting Person is the trustee and his children are beneficiaries. Held by The Maetzold 2018 Remainder Trust FBO Emily Carol Kirk of which the Reporting Person is the trustee and his child is the beneficiary. Held by The Maetzold 2018 Remainder Trust FBO Hannah Elizabeth Maetzold of which the Reporting Person is the trustee and his child is the beneficiary. Held by The Maetzold 2018 Remainder Trust FBO John Derek Maetzold of which the Reporting Person is the trustee and his child is the beneficiary. Held by The Maetzold 2018 Remainder Trust FBO Peter Douglas Maetzold of which the Reporting Person is the trustee and his child is the beneficiary. Held by DJM Grantor Retained Annuity Trust No. 5 of which the Reporting Person is the trustee and beneficiary. Held by DJM Grantor Retained Annuity Trust No. 6 of which the Reporting Person is the trustee and the beneficiaries are The Maetzold 2018 Remainder Trust FBO John Derek Maetzold, The Maetzold 2018 Remainder Trust FBO Emily Carol Kirk, The Maetzold 2018 Remainder Trust FBO Peter Douglas Maetzold and The Maetzold 2018 Remainder Trust FBO Hannah Elizabeth Maetzold. Held by DJM Grantor Retained Annuity Trust No. 7 of which the Reporting Person is the trustee and beneficiary.
SEC Form 4
FORM 4 UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940
OMB APPROVAL
OMB Number: 3235-0287
Estimated average burden
hours per response: 0.5
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
X
Check this box to indicate that a transaction was made pursuant to a contract, instruction or written plan for the purchase or sale of equity securities of the issuer that is intended to satisfy the affirmative defense conditions of Rule 10b5-1(c). See Instruction 10.
1. Name and Address of Reporting Person*
MAETZOLD DEREK J

(Last) (First) (Middle)
C/O CASTLE BIOSCIENCES, INC.
505 S. FRIENDSWOOD DRIVE, SUITE 401

(Street)
FRIENDSWOOD TX 77546

(City) (State) (Zip)
2. Issuer Name and Ticker or Trading Symbol
CASTLE BIOSCIENCES INC [ CSTL ]
5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
X Director 10% Owner
X Officer (give title below) Other (specify below)
Pres. & Chief Exec. Officer
3. Date of Earliest Transaction (Month/Day/Year)
12/15/2025
4. If Amendment, Date of Original Filed (Month/Day/Year)
6. Individual or Joint/Group Filing (Check Applicable Line)
X Form filed by One Reporting Person
Form filed by More than One Reporting Person
Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3) 2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code (Instr. 8) 4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5) 5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4) 6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 7. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V Amount (A) or (D) Price
Common Stock 12/15/2025 S(1) 18,513 D $38.747(2) 48,702 D
Common Stock 12/15/2025 S(1) 1,012 D $39.304(3) 47,690 D
Common Stock 12/16/2025 S(1) 12,821 D $38.554(4) 34,869 D
Common Stock 52,923 I By The Maetzold Descendants 2020 Trust(5)
Common Stock 44,986 I By Derek Maetzold 2020 Irrevocable Trust(6)
Common Stock 3,618 I By The Maetzold 2018 Remainder Trust FBO Emily Carol Kirk(7)
Common Stock 3,615 I By The Maetzold 2018 Remainder Trust FBO Hannah Elizabeth Maetzold(8)
Common Stock 3,615 I By The Maetzold 2018 Remainder Trust FBO John Derek Maetzold(9)
Common Stock 3,615 I By The Maetzold 2018 Remainder Trust FBO Peter Douglas Maetzold(10)
Common Stock 85,959 I By DJM Grantor Retained Annuity Trust No. 5(11)
Common Stock 18,718 I By DJM Grantor Retained Annuity Trust No. 6(12)
Common Stock 44,323 I By DJM Grantor Retained Annuity Trust No. 7(13)
Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3) 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year) 3A. Deemed Execution Date, if any (Month/Day/Year) 4. Transaction Code (Instr. 8) 5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5) 6. Date Exercisable and Expiration Date (Month/Day/Year) 7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4) 8. Price of Derivative Security (Instr. 5) 9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4) 10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4) 11. Nature of Indirect Beneficial Ownership (Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares
Explanation of Responses:
1. These transactions were made pursuant to a Rule 10b5-1 plan adopted by the Reporting Person on May 8, 2025.
2. This transaction was executed in multiple trades at prices ranging from $38.240 to $39.220, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.
3. This transaction was executed in multiple trades at prices ranging from $39.240 to $39.390, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.
4. This transaction was executed in multiple trades at prices ranging from $38.135 to $39.070, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected.
5. Held by The Maetzold Descendants 2020 Trust of which the Reporting Person's spouse is the trustee and the Reporting Person's spouse and their children are beneficiaries.
6. Held by Derek Maetzold 2020 Irrevocable Trust of which the Reporting Person is the trustee and his children are beneficiaries.
7. Held by The Maetzold 2018 Remainder Trust FBO Emily Carol Kirk of which the Reporting Person is the trustee and his child is the beneficiary.
8. Held by The Maetzold 2018 Remainder Trust FBO Hannah Elizabeth Maetzold of which the Reporting Person is the trustee and his child is the beneficiary.
9. Held by The Maetzold 2018 Remainder Trust FBO John Derek Maetzold of which the Reporting Person is the trustee and his child is the beneficiary.
10. Held by The Maetzold 2018 Remainder Trust FBO Peter Douglas Maetzold of which the Reporting Person is the trustee and his child is the beneficiary.
11. Held by DJM Grantor Retained Annuity Trust No. 5 of which the Reporting Person is the trustee and beneficiary.
12. Held by DJM Grantor Retained Annuity Trust No. 6 of which the Reporting Person is the trustee and the beneficiaries are The Maetzold 2018 Remainder Trust FBO John Derek Maetzold, The Maetzold 2018 Remainder Trust FBO Emily Carol Kirk, The Maetzold 2018 Remainder Trust FBO Peter Douglas Maetzold and The Maetzold 2018 Remainder Trust FBO Hannah Elizabeth Maetzold.
13. Held by DJM Grantor Retained Annuity Trust No. 7 of which the Reporting Person is the trustee and beneficiary.
Remarks:
/s/ Frank Stokes, Attorney-in-fact 12/17/2025
** Signature of Reporting Person Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.

FAQ

What insider transaction did Castle Biosciences (CSTL) disclose in this Form 4?

The filing reports that the president, chief executive officer and director of Castle Biosciences Inc. sold common stock in several transactions on 12/15/2025 and 12/16/2025 under a pre-established Rule 10b5-1 trading plan.

How many Castle Biosciences (CSTL) shares were sold and at what prices?

The reporting person sold 18,513 shares at a weighted-average price of $38.747, 1,012 shares at $39.304, and 12,821 shares at $38.554, with each figure reflecting weighted-average sale prices from multiple trades.

Is the Castle Biosciences (CSTL) insider sale part of a Rule 10b5-1 plan?

Yes. The filing states that these transactions were made pursuant to a Rule 10b5-1 plan adopted by the reporting person on May 8, 2025, which is a pre-arranged trading plan for equity securities.

How many Castle Biosciences (CSTL) shares does the insider own after these sales?

Following the reported transactions, the reporting person directly owns 34,869 shares of Castle Biosciences common stock and also has indirect beneficial ownership of additional shares held through multiple family and grantor retained annuity trusts.

What indirect holdings in Castle Biosciences (CSTL) are reported through trusts?

The filing lists indirect beneficial ownership in several trusts, including The Maetzold Descendants 2020 Trust, the Derek Maetzold 2020 Irrevocable Trust, multiple 2018 Remainder Trusts for family members, and DJM Grantor Retained Annuity Trusts Nos. 5, 6 and 7.

What role does the reporting person hold at Castle Biosciences (CSTL)?

The reporting person is identified as a director and as an officer of Castle Biosciences Inc., serving as President & Chief Executive Officer.