Coherus Oncology (CHRS) partners with Janssen on Phase 1b mCRPC combo trial
Filing Impact
Filing Sentiment
Form Type
8-K
Rhea-AI Filing Summary
Coherus Oncology, Inc. entered into a clinical supply agreement with Janssen Research & Development, LLC to support a Phase 1b study in metastatic castration-resistant prostate cancer. The trial will evaluate Coherus’ investigational anti-CCR8 cytolytic monoclonal antibody tagmokitug (CHS-114) in combination with Janssen’s T-cell engaging bispecific antibody pasritamig.
Under the agreement, Janssen will supply pasritamig, while Coherus will act as sponsor of the Phase 1b clinical trial in patients with metastatic castration-resistant prostate cancer. Each company keeps all commercial rights to its own compound, whether used alone or in combination therapies.
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8-K Event Classification
Item 8.01 — Other Events
1 item
Item 8.01
Other Events
Other
Voluntary disclosure of events the company deems important to shareholders but not covered by other items.
FAQ
What did Coherus Oncology (CHRS) announce in this 8-K filing?
Coherus Oncology announced a clinical supply agreement with Janssen Research & Development, LLC. The collaboration supports a Phase 1b trial testing tagmokitug (CHS-114) with Janssen’s pasritamig in patients with metastatic castration-resistant prostate cancer.
Which drugs are involved in Coherus Oncology’s agreement with Janssen?
The agreement covers tagmokitug (CHS-114), Coherus’ investigational anti-CCR8 cytolytic monoclonal antibody, and pasritamig, Janssen’s T-cell engaging bispecific antibody. These will be evaluated together in a Phase 1b study in metastatic castration-resistant prostate cancer.
What cancer indication is targeted in the Coherus–Janssen Phase 1b study?
The Phase 1b clinical study targets patients with metastatic castration-resistant prostate cancer. Coherus will sponsor the trial, evaluating tagmokitug (CHS-114) in combination with Janssen’s bispecific antibody pasritamig in this advanced prostate cancer setting.
Who will sponsor the Phase 1b clinical trial described by Coherus Oncology (CHRS)?
Coherus Oncology will be the sponsor of the Phase 1b clinical trial. Under the supply agreement, Janssen provides pasritamig, while Coherus oversees the study evaluating the combination in metastatic castration-resistant prostate cancer patients.
How are commercial rights handled in the Coherus–Janssen supply agreement?
Each party keeps all commercial rights to its own compound. Coherus retains rights to tagmokitug (CHS-114) and Janssen retains rights to pasritamig, including for use as monotherapy or in combination treatments.
Is the Coherus–Janssen collaboration a full partnership or limited to clinical supply?
The arrangement is a clinical supply agreement. Janssen will provide pasritamig for a Coherus-sponsored Phase 1b trial, and both companies retain full commercial rights to their respective compounds, including potential monotherapy or combination uses.