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Ionis Pharmaceuticals Stock Price, News & Analysis

IONS NASDAQ

Company Description

Company Overview

Ionis Pharmaceuticals, Inc. (Nasdaq: IONS) is a pioneering biotechnology company renowned for its innovative use of antisense technology and RNA-targeted therapies to develop transformative medicines for serious diseases. With a history spanning over three decades, Ionis has built its reputation on a deep understanding of disease biology, harnessing cutting-edge methodologies in gene editing and RNA modulation to address complex conditions.

Innovative Research and Development

At the heart of Ionis Pharmaceuticals is its advanced research platform, which has been instrumental in discovering and developing novel therapeutic approaches. The company has established itself as a leader in antisense drug discovery, holding over 1300 patents that underscore its commitment to innovation. Ionis collaborates with industry giants to drive breakthroughs in treatment, leveraging a strategy of precision medicine to focus on areas with high unmet need, including neurological disorders, cardiology, metabolic diseases, and rare genetic conditions.

Diverse Pipeline and Commercial Success

Ionis Pharmaceuticals has a robust portfolio that spans both marketed medicines and a dynamic development pipeline. Its portfolio includes therapies that have transformed patient care, such as the antisense drugs developed in partnership with other leading companies. The company has been involved in launching treatments for life-threatening conditions—demonstrating its ability to translate innovative research into real-world clinical applications. By combining strategic licensing, joint ventures, and independent launches, Ionis continuously advances its mission to address complex diseases with next-generation RNA therapies.

Technological Excellence and Expertise

Ionis is at the forefront of RNA-based therapeutics. The company has honed its expertise in the design and application of antisense oligonucleotides, offering a unique approach that directly targets the genetic mechanisms underlying disease. This expertise not only accelerates drug discovery but also supports the development of treatments for conditions that have been historically challenging to manage through conventional approaches.

Operational Strategy and Market Position

Ionis Pharmaceuticals operates with a multi-faceted business model that includes direct commercialization and strategic collaborations with other pharmaceutical companies. This diverse approach allows the company to manage risks while capitalizing on the significant potential of its groundbreaking therapies. Emphasizing a culture of scientific excellence and innovation, Ionis fosters an environment where multidisciplinary teams collaborate to drive forward a pipeline rich in both early-stage discoveries and late-stage clinical programs.

Competitive Landscape and Industry Impact

  • Antisense Platform: Ionis is recognized for its pioneering work in antisense technology, setting benchmarks for the industry and demonstrating a tangible impact on the treatment of serious diseases.
  • Partnerships and Collaborations: Strategic alliances with companies such as Biogen and AstraZeneca underscore its competitive edge and validate its research through successful market launches.
  • Scientific Rigor: The company’s dedication to scientific excellence, evidenced by its extensive portfolio of patents and rigorous clinical studies, reinforces its standing as a trusted innovator in biotechnology.

Commitment to Quality and Patient-Centric Approach

Ionis Pharmaceuticals is not only committed to the advancement of science but also to improving patients' lives. Its research spans conditions with significant unmet medical need, providing hope where limited treatment options previously existed. As a company, Ionis consistently demonstrates a balanced blend of deep scientific inquiry and pragmatic clinical application, ensuring that its therapies are developed with both precision and care.

Summary

The legacy of Ionis Pharmaceuticals is built on relentless innovation, strategic expertise, and a pioneering spirit in RNA-targeted therapies. Positioned at the intersection of biotechnology and clinical excellence, the company remains dedicated to its long-standing mission: to invent transformative medicines that address serious diseases and improve patient outcomes. Its comprehensive approach and operational agility have made Ionis a reference point in the field of antisense technology, continuing to influence the way modern drug development is approached worldwide.

Stock Performance

$—
0.00%
0.00
Last updated:
-30.34 %
Performance 1 year
$4.6B
Market Cap
159.0M
Shares outstanding

SEC Filings

No SEC filings available for Ionis Pharmaceuticals.

Financial Highlights

$705,138,000
Revenue (TTM)
-$453,897,000
Net Income (TTM)
-$3.04
Diluted EPS (TTM)
-$500,947,000
Operating Cash Flow
-64.37%
Net Profit Margin
-67.37%
Oper. Profit Margin

Frequently Asked Questions

What is the current stock price of Ionis Pharmaceuticals (IONS)?

The current stock price of Ionis Pharmaceuticals (IONS) is $29.57 as of April 24, 2025.

What is the market cap of Ionis Pharmaceuticals (IONS)?

The market cap of Ionis Pharmaceuticals (IONS) is approximately 4.6B.

What is the revenue (TTM) of Ionis Pharmaceuticals (IONS) stock?

The trailing twelve months (TTM) revenue of Ionis Pharmaceuticals (IONS) is $705,138,000.

What is the net income of Ionis Pharmaceuticals (IONS)?

The trailing twelve months (TTM) net income of Ionis Pharmaceuticals (IONS) is -$453,897,000.

What is the earnings per share (EPS) of Ionis Pharmaceuticals (IONS)?

The diluted earnings per share (EPS) of Ionis Pharmaceuticals (IONS) is -$3.04 on a trailing twelve months (TTM) basis.

What is the operating cash flow of Ionis Pharmaceuticals (IONS)?

The operating cash flow of Ionis Pharmaceuticals (IONS) is -$500,947,000.

What is the profit margin of Ionis Pharmaceuticals (IONS)?

The net profit margin of Ionis Pharmaceuticals (IONS) is -64.37%.

What is the operating margin of Ionis Pharmaceuticals (IONS)?

The operating profit margin of Ionis Pharmaceuticals (IONS) is -67.37%.

What is the gross margin of Ionis Pharmaceuticals (IONS)?

The gross profit margin of Ionis Pharmaceuticals (IONS) is 98.41%.

What is the current ratio of Ionis Pharmaceuticals (IONS)?

The current ratio of Ionis Pharmaceuticals (IONS) is 8.47, indicating the company's ability to pay short-term obligations.

What is the gross profit of Ionis Pharmaceuticals (IONS)?

The gross profit of Ionis Pharmaceuticals (IONS) is $693,923,000 on a trailing twelve months (TTM) basis.

What is the operating income of Ionis Pharmaceuticals (IONS)?

The operating income of Ionis Pharmaceuticals (IONS) is -$475,081,000.

What is Ionis Pharmaceuticals known for?

Ionis Pharmaceuticals is renowned for developing innovative antisense RNA therapies. Their advanced research platform has enabled them to create novel treatments for complex and serious diseases.

How does Ionis generate revenue?

The company generates revenue through a combination of direct commercialization, licensing agreements, and strategic partnerships with other pharmaceutical firms. This diversified business model supports both independent launches and collaborative projects.

What areas of medicine does Ionis focus on?

Ionis focuses on developing treatments for a range of disease areas including neurology, cardiology, metabolic disorders, and rare genetic diseases. Their innovative approach targets conditions with high unmet medical needs.

How does Ionis maintain its industry leadership?

Through a commitment to scientific excellence and a robust portfolio of patents, Ionis has established a leadership role in antisense technology and RNA-targeted therapies. Strategic collaborations and rigorous clinical trials reinforce their competitive edge.

Can you describe Ionis Pharmaceuticals' research approach?

Ionis employs a sophisticated research platform centered on antisense oligonucleotides and gene editing techniques. This approach allows them to directly target the genetic root causes of diseases and innovate effective treatment strategies.

What role do partnerships play in Ionis' operations?

Partnerships are a crucial element of Ionis' strategy. Collaborations with well-established companies help validate their research, expand market access, and accelerate the development and commercialization of innovative therapies.

How does Ionis ensure the quality of its therapies?

Ionis employs rigorous clinical research and maintains high standards in its drug development processes. Their comprehensive clinical trial programs and extensive patent portfolio exemplify their commitment to quality and safety.

What distinguishes Ionis within the biotechnology sector?

Ionis is distinguished by its pioneering role in RNA-targeted therapies and its proven antisense technology platform. A history of transformative drug launches and ongoing research in cutting-edge therapeutics set it apart in the competitive biotechnology landscape.