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Vascular Biogenics Ltd. - VBLT STOCK NEWS

Welcome to our dedicated page for Vascular Biogenics Ltd. news (Ticker: vblt), a resource for investors and traders seeking the latest updates and insights on Vascular Biogenics Ltd. stock.

Vascular Biogenics Ltd. (Nasdaq: VBLT), commonly known as VBL Therapeutics, is a leading biotechnology company headquartered at 6 Yonatan Netanyahu Street, Yehud, Center District, Israel. The company is dedicated to the discovery, development, and commercialization of innovative therapies for treating cancer and immune-inflammatory diseases. Its mission is to transform the standard of care in oncology through precision medicines.

Recently, VBL Therapeutics has made significant strides in its corporate journey. On August 14, 2023, the company announced its financial results for the second quarter ending June 30, 2023, and provided updates on its ongoing merger with Notable Labs, Inc. This merger is seen as a pivotal move, aiming to combine VBL's cutting-edge technologies with Notable's Predictive Precision Medicines Platform. The merger is anticipated to create a robust entity focused on developing a pipeline of clinical-stage precision medicines.

On September 6, 2023, the company's registration statement on Form S-4 was declared effective by the U.S. Securities and Exchange Commission (SEC), marking a critical milestone towards completing the merger. Following the approval from VBL’s shareholders at the annual and special meeting held on October 12, 2023, the merger is expected to close around October 16, 2023. Post-merger, VBL will be renamed 'Notable Labs, Ltd.' and will trade under the new symbol 'NTBL' on the Nasdaq Capital Market.

The merger with Notable Labs is expected to leverage Notable's technology to enhance VBL’s existing pipeline, offering a promising future for patients and shareholders alike. The combined organization aims to advance precision medicines that could significantly improve patient outcomes in oncology.

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VBL Therapeutics (Nasdaq: VBLT) will host a virtual R&D Day for analysts and investors on April 6, 2021, starting at 10:00am ET. The event features key presentations from CEO Dror Harats and Clinical Development VP Tami Rachmilewitz, focusing on VBL's clinical-stage pipeline, particularly the lead program, VB-111. Attendees can access the live event via VBL's investor relations website, where an archive will also be available post-event. VBL Therapeutics specializes in innovative treatments for cancer and immune-related conditions, with VB-111 currently in a Phase 3 trial for platinum-resistant ovarian cancer.

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VBL Therapeutics (Nasdaq: VBLT) announced progress in its OVAL Phase 3 study for VB-111, targeting platinum-resistant ovarian cancer, reporting over 50% response rates among 200+ patients. A Data Safety Monitoring Committee review confirmed no safety issues, allowing trial continuation. Further, VBL initiated Phase 2 studies for VB-111 in glioblastoma and VB-201 for COVID-19. Financially, VBL reported revenues of $922,000 for 2020, up from $562,000 in 2019, with R&D expenses rising to $19.7 million. The company had cash reserves of $30.8 million, sufficient to fund operations into Q4 2022.

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VBL Therapeutics (Nasdaq: VBLT) will announce its fourth quarter and full year results for 2020 on March 25, 2021. CEO Dror Harats and CFO Amos Ron will host a conference call at 8:30 am ET to discuss the results and provide updates. VBL Therapeutics focuses on developing first-in-class treatments for unmet cancer and immune/inflammatory needs, with its lead product candidate, VB-111, currently in a Phase 3 trial for platinum-resistant ovarian cancer.

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VBL Therapeutics (Nasdaq: VBLT) announced its participation in three upcoming virtual investor conferences:

  • H.C Wainwright Global Life Sciences Conference on March 9, 2021, with on-demand presentations starting at 7:00 a.m. ET.
  • 33rd Annual Roth Conference on March 15, 2021, featuring a panel on cancer at 10:00 a.m. ET.
  • 31st Annual Oppenheimer Healthcare Conference on March 16, 2021, with a fireside chat at 8:00 a.m. ET.

Webcasts are accessible on the Company’s Investor Relations page.

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VBL Therapeutics (Nasdaq: VBLT) announced promising results from the interim analysis of the OVAL study, a Phase 3 trial evaluating VB-111 in patients with recurrent platinum-resistant ovarian cancer. The analysis revealed a CA-125 response rate of at least 58% in the VB-111 treatment arm, exceeding the required 10% advantage over placebo. The Data and Safety Monitoring Committee has recommended the continuation of the trial. The trial aims to enroll around 400 patients, and VB-111 is a novel gene therapy with potential to significantly improve treatment outcomes.

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VBL Therapeutics (Nasdaq: VBLT) has initiated patient dosing for a Phase 2 clinical trial of ofranergene obadenovec (VB-111) aimed at treating recurrent glioblastoma multiforme (rGBM). The trial, sponsored by Dana-Farber Cancer Institute, will take place across seven U.S. medical centers. It builds on previous successful trials and includes comparisons to standard care. Key endpoints include progression-free survival and overall survival metrics. VB-111 has shown promise in its dual-targeting approach and has received multiple designations for its therapeutic potential.

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VBL Therapeutics (Nasdaq: VBLT) announced positive results from the independent Data Safety Monitoring Committee (DSMC) review of its OVAL Phase 3 study of VB-111 for recurrent ovarian cancer. The DSMC found no safety concerns and recommended the trial's continuation. The study, which aims to enroll 400 patients, has shown a response rate of 53% across both arms, with rates in the treatment arm exceeding 58%. The next DSMC review is anticipated in Q3 2021.

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VBL Therapeutics (Nasdaq: VBLT) has commenced a Phase 2 study of its investigational oral immune-modulator VB-201 to treat severe COVID-19. The trial aims to evaluate VB-201's efficacy in preventing clinical deterioration and reducing complications in affected patients. VB-201 previously demonstrated promise in over 600 subjects during a Phase 2 trial targeting vascular inflammation. The study addresses the urgent global need for effective COVID-19 treatments, particularly in light of vaccine accessibility issues and evolving viral mutations.

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Ovarian cancer poses serious challenges globally, with over 240,000 diagnoses annually. BioVaxys Technology Corp. has initiated a clinical program for BVX-0918A, aiming to address unmet needs in Stage III and IV ovarian cancer. The company plans to seek compassionate use approval in the EU and will submit a clinical trial application later this year. Additionally, they completed a preclinical program for the SARS-CoV-2 vaccine candidate BVX-0320 with promising results. Ongoing clinical trials and advancements in immunotherapy are pivotal in shaping the future of cancer treatment.

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VBL Therapeutics has entered into an Ordinary Share Purchase Agreement with Aspire Capital Fund, LLC, extending its cash runway to Q1 2023. This agreement allows Aspire to purchase up to $20 million of ordinary shares over a 30-month period, providing VBL the flexibility to finance its ongoing clinical studies, particularly the OVAL phase 3 study focused on VB-111 in ovarian cancer. The deal does not impose financial covenants or penalties, offering VBL a strategic advantage in securing capital for its projects.

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FAQ

What is the market cap of Vascular Biogenics Ltd. (vblt)?

The market cap of Vascular Biogenics Ltd. (vblt) is approximately 12.1M.

What does Vascular Biogenics Ltd. specialize in?

Vascular Biogenics Ltd., also known as VBL Therapeutics, focuses on developing therapies for cancer and immune-inflammatory diseases.

Where is Vascular Biogenics Ltd. located?

The company is headquartered at 6 Yonatan Netanyahu Street, Yehud, Center District, Israel.

What recent corporate event did VBL announce?

VBL announced financial results for Q2 2023 and updates on its merger with Notable Labs, expected to close in mid-October 2023.

What is the significance of the merger with Notable Labs?

The merger aims to combine VBL's and Notable's technologies to develop precision medicines, improving the standard of care in oncology.

When is the merger expected to be completed?

The merger is expected to close around October 16, 2023.

What will VBL be renamed after the merger?

Post-merger, VBL will be renamed 'Notable Labs, Ltd.'

What will be the new trading symbol for VBL after the merger?

The new trading symbol will be 'NTBL' on the Nasdaq Capital Market.

What recent approvals did VBL receive for the merger?

The U.S. SEC declared VBL's Form S-4 effective, and VBL’s shareholders overwhelmingly approved the merger in October 2023.

Who is the CEO of VBL Therapeutics?

Prof. Dror Harats, M.D. is the Chief Executive Officer of VBL Therapeutics.

How will the merger benefit patients?

The merger aims to develop a pipeline of clinical-stage precision medicines, potentially transforming the standard of care in oncology and improving patient outcomes.

Vascular Biogenics Ltd.

Nasdaq:VBLT

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12.11M
57.68M
13.48%
14.05%
0.32%
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