Welcome to our dedicated page for Xencor news (Ticker: XNCR), a resource for investors and traders seeking the latest updates and insights on Xencor stock.
Overview
Xencor Inc is a clinical-stage biopharmaceutical company dedicated to the discovery and development of engineered antibody therapeutics. With a strong emphasis on protein engineering and innovative antibody therapeutics, Xencor focuses on improving treatment options for patients suffering from cancer and autoimmune diseases through its proprietary XmAb technology platform.
Proprietary XmAb Technology Platform
Xencor’s XmAb platform represents a significant advancement in antibody engineering. The technology allows for the augmentation of natural antibody immune functions while preserving a high degree of identity to naturally occurring antibodies. This precise and strategic modification results in antibodies with enhanced potency, improved safety profiles, and extended half-lives. The dual emphasis on maintaining the beneficial aspects of natural antibody structures along with the integration of novel functionalities enables the company to develop biotherapeutic candidates that are differentiated and potentially capable of breakthrough performance.
Pipeline and Collaborations
The company has established a robust pipeline consisting of multiple product candidates, many of which are advanced into clinical evaluations. Xencor’s approach is underpinned by a diversified business model that includes revenue generation from collaboration agreements, product licensing, and technology licensing. This multi-faceted strategy not only facilitates rapid clinical development but also leverages partnerships with global pharmaceutical entities to expand the reach and applicability of its engineered therapeutics.
Business Model and Market Position
Operating in the highly specialized realm of biotherapeutics, Xencor positions itself as an innovator in the field of antibody engineering. Its focus on designing antibodies that target new biological mechanisms allows it to meet unmet medical needs with improved therapeutic profiles. The company’s revenue model is strongly based on collaboration and licensing, which supports both internal development and industry-wide integration. By aligning cutting-edge research with strategic partnerships, Xencor demonstrates a commitment to enhancing patient outcomes and significantly contributing to the biopharmaceutical landscape.
Technological and Clinical Significance
The XmAb platform is central to Xencor’s technological prowess. The ability to finely tune antibody functions offers a scalable and adaptable solution to address various indications, such as autoimmune disorders and cancer. In doing so, Xencor not only advances clinical practice but also lays the foundation for future innovations in the field of biologics discovery. The company’s clear focus on harnessing innovative protein engineering techniques underscores its depth of expertise and solidifies its position as an important participant in the biotherapeutic market.
Key Differentiators
- Innovative Platform: The XmAb technology provides a unique blend of increasing biological activity while retaining the safety benefits of natural antibodies.
- Diversified Business Model: Revenue streams from collaborations, technology licensing, and product licensing enhance the company’s resilience and market adaptability.
- Strategic Collaborations: Partnerships with pharmaceutical leaders amplify the reach and clinical potential of Xencor’s product candidates.
- Clinical-Stage Focus: A robust clinical pipeline demonstrates the company's commitment to translating innovative research into tangible treatment options.
Conclusion
In summary, Xencor Inc stands out in the biopharmaceutical realm through its commitment to developing advanced engineered antibody therapeutics. The proprietary XmAb platform not only highlights its expertise in protein engineering but also reinforces its strategic position within a competitive industry. By integrating deep technological insight with a collaborative business model, Xencor continues to build a diversified portfolio that aims to address some of the most pressing medical challenges.
Xencor, a clinical-stage biopharmaceutical company focused on engineered monoclonal antibodies and cytokines for treating cancer and autoimmune diseases, has announced its participation in several investor events.
- Bernstein CD28 Day: Presentation on August 9 at 1:00 p.m. ET.
- Wedbush PacGrow Healthcare Conference: Panel on August 10 at 1:10 p.m. ET.
- BTIG Virtual Biotechnology Conference: Presentation on August 10 at 3:30 p.m. ET.
- Canaccord Genuity Conference: Presentation on August 11 at 4:30 p.m. ET.
- Piper Sandler West Coast Bus Tour: Presentation on August 12 at 4:00 p.m. ET.
A webcast of the Canaccord presentation will be available on Xencor's website.
Xencor, Inc. (NASDAQ: XNCR) will release its second quarter 2021 financial results post-market on August 4, 2021. A conference call is scheduled for 4:30 p.m. ET to discuss these results and provide a corporate update. The live call can be accessed via phone or a webcast on the company's website. Xencor is a clinical-stage biopharmaceutical firm focusing on engineered monoclonal antibodies and cytokines targeting cancer and autoimmune diseases, with 22 candidates in clinical development leveraging its XmAb® technology.
Xencor, Inc. (NASDAQ: XNCR) announced that Dr. Bassil Dahiyat, president and CEO, will present a corporate overview at the Jefferies Virtual Healthcare Conference on June 3, 2021, at 1:00 p.m. ET. The presentation will cover Xencor's focus on developing engineered monoclonal antibodies and cytokines for cancer and autoimmune diseases. A webcast of the event will be available on the company's website, with a replay accessible for at least 30 days following the event.
Xencor, Inc. (NASDAQ: XNCR) announced that the FDA has granted emergency use authorization for sotrovimab, an engineered monoclonal antibody developed with Vir Biotechnology and GlaxoSmithKline to treat mild-to-moderate COVID-19 in high-risk patients. While not approved, sotrovimab shows an 85% reduction in hospitalization or death based on Phase 3 trial data. Xencor has licensed its Xtend technology to Vir to enhance antibody performance. The EUA will last as long as the COVID-19 emergency declaration is in effect.
Xencor, a clinical-stage biopharmaceutical company (NASDAQ:XNCR), entered a licensing agreement with Bristol-Myers Squibb (NYSE:BMY) for its Xtend™ Fc technology to extend the half-life of the SARS-CoV-2 mAb Duo, designed for COVID-19 treatment. This antibody combination, discovered at Rockefeller University, is currently in Phase 1 clinical evaluation. Xencor, eligible for royalties from sales, emphasizes that its technology improves therapeutic performance, potentially lowering costs for antiviral therapies. The partnership aims to address urgent medical needs, particularly in the pandemic context.
Xencor, a clinical-stage biopharmaceutical company focusing on engineered monoclonal antibodies and cytokines for cancer and autoimmune diseases, announced that its CEO, Bassil Dahiyat, will participate in a virtual fireside chat at the 2021 RBC Capital Markets Global Healthcare Virtual Conference. The event is set for May 19, 2021, at 1:20 p.m. ET. Investors can access a live webcast on the company's website, with a replay available for 30 days afterward. Xencor has 21 clinical candidates utilizing its XmAb technology.
Xencor, a clinical-stage biopharmaceutical company, reported Q1 2021 financial results, achieving a total revenue of $34 million, an increase from $32.4 million in Q1 2020. The net loss narrowed to $2.5 million or $(0.04) per share, compared to a loss of $8.1 million the previous year. Cash and equivalents amounted to $577.1 million. Recently, Xencor initiated a Phase 1 study for XmAb564 and presented preclinical data at the AACR meeting. Future clinical studies are planned for XmAb717 and Tidutamab.
Xencor, Inc. (NASDAQ: XNCR) has initiated a Phase 1 clinical study for XmAb564, targeting autoimmune diseases. The first subject has been dosed in this randomized, double-blind, placebo-controlled trial, which evaluates the safety and tolerability of XmAb564 in healthy volunteers. XmAb564 is designed to selectively activate regulatory T cells while minimizing activation of other immune cells, aimed at improving therapeutic outcomes. Preliminary studies indicate it has favorable pharmacologic properties and promotes sustained Treg proliferation.
Xencor, Inc. (NASDAQ: XNCR) announced its plans to release first quarter 2021 financial results after market close on May 5, 2021. A conference call will be held the same day at 4:30 p.m. ET to discuss the results and provide a corporate update. Interested parties can access the call by dialing (877) 359-9508 or through an online webcast available on Xencor's website. The company is focused on developing engineered monoclonal antibodies and cytokines for cancer and autoimmune disease treatments, with 21 candidates in clinical development.
Xencor, Inc. (NASDAQ:XNCR) announced new data presentation from its preclinical bispecific antibody and IL-12-Fc cytokine programs at the AACR Annual Meeting. The data showcases the potential of CD28 and XmAb 2+1 platforms, emphasizing their engineered cytokines' enhanced therapeutic indices. Notably, Xencor plans to submit an IND for their XmAb819 bispecific antibody in 2021 and start a Phase 1 study in early 2022. The IL-12-Fc fusions showed significant anti-tumor activity in preclinical models, indicating a promising future for Xencor's innovations in cancer therapies.
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