Waters Sets New Standards for High Resolution Performance and Speed with Xevo MRT Mass Spectrometer

Rhea-AI Summary

Waters has unveiled its new Xevo MRT Mass Spectrometer at the 72nd ASMS Conference. This next-generation instrument employs advanced multi-reflecting time-of-flight technology, offering up to 6x higher resolution and 2x mass accuracy compared to competitors. The Xevo MRT enables faster processing of large sample cohorts, essential for biomedical and epidemiology research. It delivers high resolution, speed, and sensitivity, ensuring reliable data for complex disease studies. The system is compatible with Waters' software, columns, and third-party applications, facilitating comprehensive workflows for metabolomic and lipidomic research. The Xevo MRT will be available for shipment in the second half of 2024.

Positive

• New Xevo MRT Mass Spectrometer offers 6x higher resolution and 2x mass accuracy, enhancing scientific research capabilities.
• Improves efficiency by enabling faster processing of large sample cohorts.
• Compatible with Waters' software, columns, and third-party applications, providing flexible and comprehensive workflows.
• High resolution, speed, and sensitivity of the Xevo MRT ensure reliable data for complex disease studies.
• Supports universal data-sharing via mzML file formats, facilitating integration with various informatics software.
• Orderable today for shipment in the second half of 2024, ensuring timely availability for researchers.

Negative

• No specific financial data or projections provided, limiting insights into potential revenue impact.
• Potentially high cost of Xevo MRT may be a barrier for smaller research institutions or labs with budgets.

Financial Analyst

Waters Corporation's introduction of the Xevo MRT Mass Spectrometer aligns with the company's strategy to stay at the forefront of high-tech laboratory instruments. Analyzing its financial impact, this product could significantly boost Waters' revenue streams by catering to large-cohort biomedical research and epidemiology-type studies. The potential for increased sales volume arises from the higher resolution and speed offered, making it appealing for institutions seeking to improve their research capabilities. Additionally, the product's ability to integrate with existing Waters software and third-party applications could lead to cross-selling opportunities. However, the cost of adoption by new users and potential competition from other established brands could be drawbacks. Investors should monitor how quickly this product gains traction in the market.

Tech Expert

The Xevo MRT Mass Spectrometer employs next-generation technology, enhancing both resolution and speed dramatically. The multi-reflecting time-of-flight (MRT) technology, combined with hybrid quadrupole time-of-flight (QTof) technologies, marks a significant innovation. The ability to achieve 100,000 full width half maximum (FWHM) resolution at 100 Hz MS/MS scan speed is impressive. This dual capability could revolutionize high-throughput separations and data quality, essential for complex biological analyses. Moreover, the design's emphasis on sensitivity and accuracy without compromising speed addresses a significant need in the scientific community. For laboratories and research institutions, the Xevo MRT's performance can translate to more robust data and faster time-to-results.

Market Research Analyst

The announcement of the Xevo MRT Mass Spectrometer comes at a time when the demand for advanced analytical instruments is rising, especially in biomedical research and epidemiology studies. This product could differentiate Waters in the competitive mass spectrometry market. The integration with Waters' software, columns and high throughput systems could enhance its market appeal. However, it's important to note that while the high-resolution and speed are significant selling points, the market adoption will depend on the product's price point and the availability of competitive alternatives. Potential customers are likely to weigh the benefits of enhanced performance against implementation costs.

News Summary:

• Waters Xevo™ MRT Mass Spectrometer employs next-generation multi-reflecting time-of-flight technology to deliver class-leading combination of high resolution and speed without compromising analytical performance.ⁱ
• Delivers up to 6x resolution at maximum speed and up to 2x mass accuracy of competitive systems,ⁱⁱ enabling scientists to process more samples in less time for large-cohort biomedical research and epidemiology-type studies.
• Complete workflows available for metabolomic, lipidomic, and metabolite identification enables customer flexibility and convenience using Waters™ software, columns, and instruments for high throughput separations, and universal data-sharing with third-party software applications.

ANAHEIM, Calif., and MILFORD, Mass., June 3, 2024 /PRNewswire/ -- 72^nd ASMS Conference on Mass Spectrometry and Allied Topics – Waters Corporation (NYSE: WAT) today unveiled the Xevo™ MRT, its highest-performing benchtop mass spectrometer (MS), setting new standards for delivering high resolution and speed, critical for large population and epidemiology-type studies. It builds on the innovative technology pioneered by the Waters SELECT SERIES™ MRT MS. The new Xevo MRT MS combines the raw power and resolution speed of multi-reflecting time-of-flight (MRT) and hybrid quadrupole time-of-flight (QTof) technologies within a flexible benchtop platform.

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"Understanding complex diseases requires analysis of thousands of samples from large human cohorts to provide statistically valid studies. This puts increased pressure on drug discovery scientists to deliver high-quality data in shorter run times," said Dr. Udit Batra, CEO and President of Waters Corporation. "The Xevo MRT mass spectrometer is a next generation QTof built from the ground up to address this unmet need, delivering high resolution and speed without compromising analytical performance. Its multi-reflecting time-of-flight design enables simultaneous high sensitivity, high resolution, and speed in a small footprint, accelerating time-to-results and ensuring high-quality experimental outcomes."

The Xevo MRT system delivers a class-leadingⁱⁱⁱ 100,000 full width half maximum (FWHM) resolution at 100 Hz MS/MS scan speed and <500 parts per billion (ppb) mass accuracy. This enables deeper probing of biologically relevant concentrations with high levels of mass accuracy, independent of acquisition rate.

"A range of mass spec approaches are available for metabolomic, lipidomic, and metabolite identification studies, yet all require compromises to be made - either in data quality or analytical efficiency," said Professor Perdita Barran, Chair of Mass Spectroscopy in the University of Manchester (UK) Department of Chemistry and Director of the Michael Barber Centre for Collaborative Mass Spectrometry at the Manchester Institute of Biotechnology. "The Xevo MRT MS is impressive technology capable of higher sample throughput combined with extremely high precision, which can significantly advance target validation and phenotyping studies. The increase in scan speed and data quality are critical as it can allow us to run more samples in less time without compromising confidence in our data and we are very excited by how this is allowing us to accelerate the development of a diagnostic test for Parkinson's Disease."

The innovative multi-reflecting time-of-flight design of the Xevo MRT MS offers scientists the power to work at maximum resolution with high sensitivity and fast data acquisition rates. This helps ensure confident identification of analytes across a range of samples and complex matrices and generate comprehensive and highly accurate mass data for scientific interpretation.

Waters offers complete workflows for metabolomic, lipidomic, and metabolite identification for the Xevo MRT MS, alongside Waters high throughput ACQUITY™ UPLC™ Systems and UPLC Column chemistries and waters_connect™ Software for data acquisition, processing, and reporting. The system supports universal data-sharing via mzML file formats with third-party informatics software, including popular applications from Mass Analytica™ such as its MARS, Lipostar2, and MassMetaSite software offerings.

The Waters Xevo MRT MS is orderable today for shipment in the second half of 2024.

Additional Resources

• Learn more at www.waters.com/XevoMRT
• View the Waters ASMS 2024 Online Press Kit for downloadable product photos, spec sheets, infographics and videos.
• Read the solution brief: "A High-Throughput Lipidomic Workflow Using the Waters Xevo MRT Mass Spectrometer"
• Follow and connect with Waters via LinkedIn, Twitter, and Facebook

About Waters Corporation (www.waters.com)

Waters Corporation (NYSE: WAT), a global leader in analytical instruments and software, has pioneered chromatography, mass spectrometry, and thermal analysis innovations serving the life, materials, food, and environmental sciences for more than 65 years. With approximately 7,700 employees worldwide, Waters operates directly in 35 countries, including 15 manufacturing facilities, and with products available in more than 100 countries.

Waters, Xevo, SELECT SERIES, ACQUITY, UPLC, and waters_connect are trademarks of Waters Technologies Corporation. Mass Analytica is a trademark of Mass Spec Analytica, S.L.

Contact:
Janice Foley
Senior Public Relations Manager, Corporate Communications
Waters Corporation
janice_foley@waters.com
+1.617.823.5555

ⁱ Estimates based on Xevo MRT MS performance comparison to competitor instruments @100Hz @m/z 956 = 100K FWHM and <500ppb mass accuracy.
ⁱⁱ Xevo MRT MS Resolution of 100K FWHM @ m/z 956 is up to 1.5x to 6x competitor instruments @100Hz; Xevo MRT Mass Accuracy of <500ppb is 2x competitor systems @ 1ppm.
ⁱⁱⁱ Xevo MRT MS Resolution of 100K FWHM @ m/z 956 is up to 1.5x to 6x competitor instruments @100Hz; Xevo MRT Mass Accuracy of <500ppb is 2x competitor systems @ 1ppm.

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SOURCE Waters Corporation

FAQ

What is the new product announced by Waters ?

Waters announced the Xevo MRT Mass Spectrometer.

What are the key features of the Xevo MRT Mass Spectrometer?

The Xevo MRT offers up to 6x higher resolution, 2x mass accuracy, and faster processing for large sample cohorts.

When will the Xevo MRT Mass Spectrometer be available for shipment?

The Xevo MRT Mass Spectrometer will be available for shipment in the second half of 2024.

How does the Xevo MRT Mass Spectrometer benefit scientific research?

It delivers high resolution, speed, and sensitivity, enabling reliable data for complex disease studies and faster processing of large sample cohorts.

What compatibility does the Xevo MRT Mass Spectrometer offer?

It is compatible with Waters' software, columns, and third-party applications for comprehensive workflows.