STOCK TITAN

VolitionRx Announces Collaboration with Sysmex

Rhea-AI Impact
(Moderate)
Rhea-AI Sentiment
(Positive)
Tags
partnership

VolitionRx (NYSE American: VNRX) announced a collaboration with Sysmex (TYO: 6869) to optimize Volition's Nu.Q® NETs H3.1 assay on the Sysmex diagnostic platform. The partnership supports Volition's strategy to out-license its NETs test globally and target diseases associated with NETosis, including sepsis.

According to Volition, the Nu.Q NETs test aims to aid clinical decision-making, support personalized care, and offer low-cost monitoring of patient condition. The company cites a $3.8 billion Total Addressable Market for the Nu.Q NETs assay.

Loading...
Loading translation...

AI-generated analysis. Not financial advice.

Positive

  • None.

Negative

  • None.

News Market Reaction – VNRX

-2.14%
5 alerts
-2.14% News Effect
+3.7% Peak Tracked
-17.3% Trough Tracked
-$375K Valuation Impact
$17.15M Market Cap
0.6x Rel. Volume

On the day this news was published, VNRX declined 2.14%, reflecting a moderate negative market reaction. Argus tracked a peak move of +3.7% during that session. Argus tracked a trough of -17.3% from its starting point during tracking. Our momentum scanner triggered 5 alerts that day, indicating moderate trading interest and price volatility. This price movement removed approximately $375K from the company's valuation, bringing the market cap to $17.15M at that time.

Data tracked by StockTitan Argus on the day of publication.

Key Figures

Nu.Q NETs TAM: $3.8 billion
1 metrics
Nu.Q NETs TAM $3.8 billion Total Addressable Market for Nu.Q® NETs assay cited in collaboration release

Peers on Argus

Sector peers show mixed moves with declines in ICCM (-2.74%), LUNG (-3.85%) and ...
1 Down

Sector peers show mixed moves with declines in ICCM (-2.74%), LUNG (-3.85%) and APYX (-8.7%), while TELA (+12.18%) and CTSO (+5.9%) trade higher, suggesting stock-specific factors rather than a unified sector trend.

Historical Context

5 past events · Latest: Jun 07 (Negative)
Pattern 5 events
Date Event Sentiment Move Catalyst
Jun 07 Equity offering Negative -20.4% Dilutive public offering of shares and warrants priced at $1.55.
Jun 03 IP / patent news Positive -10.3% New patent filing protecting Nu.Q® NETs test for Ebola triage use.
May 27 Commercial update Positive +0.0% Highlight of Q1 revenue growth and large multi-billion-dollar TAMs.
May 14 Earnings update Neutral -9.1% Q1 2026 financials with higher revenue but continued losses and cash burn.
May 11 Conference call notice Neutral -8.9% Scheduling of earnings and business update conference call.
Pattern Detected

Recent news, including offerings and patent/commercial updates, has often been followed by flat or negative price reactions, even on seemingly positive developments.

Recent Company History

Over the last few months, VolitionRx has balanced financing needs with commercial and clinical progress. A $4.6 million public offering and use of warrants followed earlier disclosures of Q1 2026 revenue near $1.0 million and growing Nu.Q® NETs and Vet programs. Patent protection and commercial momentum across multi-billion-dollar TAMs have not consistently translated into positive next-day price moves. Today’s Sysmex collaboration extends the Nu.Q® NETs partnership theme within this financing-heavy backdrop.

Regulatory & Risk Context

Active S-3 Shelf · Short Interest: 8.11%
Shelf Active
Short Interest
8.11% of float
0% 15% 30%+
low as of 2026-05-29 Days to cover: 1.33
Active S-3 Shelf Registration 2026-02-09

An effective Form S-3 shelf dated 2026-02-09 registers 17,968,090 common shares for resale by existing investors, primarily holders of convertible notes and warrants such as Lind Global Asset Management. The company receives no proceeds from these resale transactions, but the registered block can create share overhang if large amounts are sold into the market.

Market Pulse Summary

This announcement highlights VolitionRx’s collaboration with Sysmex to optimize the Nu.Q® NETs H3.1 ...
Analysis

This announcement highlights VolitionRx’s collaboration with Sysmex to optimize the Nu.Q® NETs H3.1 assay on a major diagnostics platform, targeting diseases linked to NETosis and a cited $3.8 billion Total Addressable Market. It builds on earlier Nu.Q® NETs and commercial updates while the company continues to manage financing needs through offerings and an effective resale shelf. Investors may watch for concrete commercialization milestones, regulatory progress, and partner-driven adoption metrics from this collaboration.

Key Terms

in vitro diagnostics, neutrophil extracellular traps, NETosis, assay
4 terms
in vitro diagnostics medical
"Sysmex (TYO: 6869), a leader in global in vitro diagnostics, to optimize"
In vitro diagnostics are medical tests performed on samples taken from the body—such as blood, urine or tissue—using instruments or kits outside the patient to detect disease, measure biomarkers or guide treatment decisions. They matter to investors because sales, regulatory approvals, reimbursement rules and adoption rates drive companies’ revenue and margins much like product launches and consumer demand in other industries; advances can create growth or disruption in healthcare markets.
neutrophil extracellular traps medical
"where Neutrophil Extracellular Traps ("NETS") play such an important role."
Neutrophil extracellular traps (NETs) are web-like strands of DNA and proteins expelled by certain white blood cells to trap and neutralize invading germs, like a spider spinning a sticky web to catch insects. For investors, NETs matter because they are linked to inflammation, blood clots and chronic disease, making them potential targets for new diagnostics and therapies and a factor in safety and efficacy assessments for drug and device development.
NETosis medical
"optimization phase in diseases associated with NETosis. NETosis is implicated"
Netosis is a process where a type of white blood cell ejects a sticky web-like mesh to trap germs, sacrificing itself in the process. While intended as a protective response, these nets can also spark inflammation, blood clots or tissue damage, so they matter to investors because drugs that alter netosis can become new therapies or safety risks, affect clinical trial outcomes, and influence regulatory and market value for companies working on related diagnostics or treatments.
assay technical
"to optimize Volition's Nu.Q® NETs H3.1 assay on the Sysmex platform."
An assay is a laboratory test that detects or measures how much of a specific substance is present or how well something performs, like measuring a drug’s concentration, a material’s purity, or a biomarker’s level. For investors, assay results act like a thermometer or quality check: they provide objective evidence about a product’s effectiveness, safety, or manufacturing consistency, and can strongly influence regulatory approval, market acceptance, and company valuation.

AI-generated analysis. Not financial advice.

See more from StockTitan in Google Search and AI answers. Adds StockTitan as a preferred source · opens Google
Add on Google

HENDERSON, Nev., June 17, 2026 /PRNewswire/ -- VolitionRx Limited (NYSE AMERICAN: VNRX) ("Volition"), a multi-national epigenetics company, announces a collaboration with Sysmex (TYO: 6869), a leader in global in vitro diagnostics, to optimize Volition's Nu.Q® NETs H3.1 assay on the Sysmex platform.

Gael Forterre, Chief Commercial Officer, Volition commented:

"We are proud to have entered into this agreement with Sysmex, as we implement our strategy to out license our proprietary Nu.Q® NETs test to large companies with a worldwide presence, to leverage their knowledge of specific diseases, product development, regulatory experience and their installed base of proprietary analyzers. Sysmex is a global leader in the field of in vitro diagnostics for hemostasis and thrombosis, among other diseases, where Neutrophil Extracellular Traps ("NETS") play such an important role.

"Following the successful transfer of our Nu.Q® NETs assay onto Sysmex's platform we are delighted to commence the optimization phase in diseases associated with NETosis. NETosis is implicated in a wide range of diseases, including sepsis and other acute and chronic diseases.

"We believe that Volition's Nu.Q® NETs test could provide not only improved diagnostic information to aid clinical decision-making and personalized care, but could also be a low-cost test to continue to monitor a patient's condition.

"The commercial opportunity for the Nu.Q® NETs assay is significant, with a Total Addressable Market of $3.8 billion[1].

"It is exciting to progress the collaboration with Sysmex and we look forward to a fruitful long-term partnership together."
 

[1] Data on File, Volition TAM Model
 

About Sysmex

Sysmex Corporation, headquartered in Kobe, Japan, is a global leader in in vitro diagnostics. Since its foundation in 1968, Sysmex has focused on diagnostics as the core of its business, and today it supports the health of people in over 190 countries and regions worldwide. Sysmex continues to innovate in diagnostics, and to collaboratively create unique values in the areas of personalized medicine and novel treatments, under its long-term vision of "Together for a better healthcare journey." Through its unique technology, solutions, and co-creation with various partners, Sysmex delivers new value and addresses the universal desire of people to live longer and healthier lives. For more information about Sysmex, please visit www.sysmex.co.jp/en/.

About Volition

Volition is a multi-national company focused on advancing the science of epigenetics. Volition is dedicated to saving lives and improving outcomes for people and animals with life-altering diseases through earlier detection, as well as disease and treatment monitoring.

Through its subsidiaries, Volition is developing and commercializing simple, easy to use, cost-effective blood tests to help detect and monitor a range of diseases, including some cancers and diseases associated with NETosis, such as sepsis. Early detection and monitoring have the potential not only to prolong the life of patients, but also to improve their quality of life.

Volition's research and development activities are centered in Belgium, with an innovation laboratory and office in the U.S. and an office in London.

The contents found at Volition's website address are not incorporated by reference into this document and should not be considered part of this document. Such website address is included in this document as an inactive textual reference only.

Media Enquiries: Louise Batchelor, Volition, mediarelations@volition.com +44 (0)7557 774620

Safe Harbor Statement

Statements in this press release or associated video or link may be "forward-looking statements" within the meaning of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended, that concern matters that involve risks and uncertainties that could cause actual results to differ materially from those anticipated or projected in the forward-looking statements. Words such as "expects," "anticipates," "intends," "plans," "aims," "targets," "believes," "seeks," "estimates," "optimizing," "potential," "goal," "suggests," "could," "would," "should," "may," "will" and similar expressions identify forward-looking statements. These forward-looking statements relate to, among other topics, Volition's expectations related to revenue opportunities and growth, the effectiveness and availability of Volition's blood-based diagnostic, prognostic and disease monitoring tests, Volition's ability to develop and successfully commercialize such test platforms for early detection of cancer and other diseases as well as serving as a diagnostic, prognostic or disease monitoring tools for such diseases, Volition's expectations regarding future publications, Volition's success in securing licensing and/or distribution agreements with third parties for its products, and Volition's expectations regarding the terms of such agreements. Volition's actual results may differ materially from those indicated in these forward-looking statements due to numerous risks and uncertainties, including, without limitation, results of studies testing the efficacy of its tests. For instance, if Volition fails to develop and commercialize diagnostic, prognostic or disease monitoring products, it may be unable to execute its plan of operations. Other risks and uncertainties include Volition's failure to obtain necessary regulatory clearances or approvals to distribute and market future products; a failure by the marketplace to accept the products in Volition's development pipeline or any other diagnostic, prognostic or disease monitoring products Volition might develop; Volition's failure to secure adequate intellectual property protection; Volition will face fierce competition and Volition's intended products may become obsolete due to the highly competitive nature of the diagnostics and disease monitoring market and its rapid technological change; downturns in domestic and foreign economies; and other risks, including those identified in Volition's most recent Annual Report on Form 10-K and Quarterly Reports on Form 10-Q, as well as other documents that Volition files with the Securities and Exchange Commission. These statements are based on current expectations, estimates and projections about Volition's business based, in part, on assumptions made by management. These statements are not guarantees of future performance and involve risks, uncertainties and assumptions that are difficult to predict. Forward-looking statements are made as of the date of this release, and, except as required by law, Volition does not undertake an obligation to update its forward-looking statements to reflect future events or circumstances.

Nu.Q®, Nucleosomics™, Capture-PCR™, Capture-Seq™ and rNuQ™and their respective logos are trademarks and/or service marks of VolitionRx Limited and its subsidiaries. All other trademarks, service marks and trade names referred to in this press release or associated video or link are the property of their respective owners. Additionally, unless otherwise specified, all references to "$" refer to the legal currency of the United States of America.

Cision View original content:https://www.prnewswire.com/news-releases/volitionrx-announces-collaboration-with-sysmex-302803026.html

SOURCE VolitionRx Limited

FAQ

What did VolitionRx (NYSE American: VNRX) announce about its collaboration with Sysmex?

VolitionRx announced a collaboration with Sysmex to optimize its Nu.Q NETs H3.1 assay on the Sysmex platform. According to Volition, this agreement supports its strategy to out-license the Nu.Q NETs test through partners with global reach and regulatory expertise.

What is the goal of the VolitionRx and Sysmex Nu.Q NETs H3.1 assay collaboration?

The collaboration aims to optimize VolitionRx's Nu.Q NETs H3.1 assay on Sysmex's diagnostic platform. According to Volition, this optimization targets diseases associated with NETosis and is intended to enhance diagnostic information and support personalized care and condition monitoring.

Which diseases are targeted in the VolitionRx (VNRX) Nu.Q NETs collaboration with Sysmex?

The collaboration focuses on diseases associated with NETosis, including sepsis and other acute and chronic conditions. According to Volition, Neutrophil Extracellular Traps play an important role in hemostasis, thrombosis and related diseases, making them a key area for the Nu.Q NETs assay.

What is the market opportunity for VolitionRx's Nu.Q NETs assay (VNRX)?

VolitionRx cites a Total Addressable Market of $3.8 billion for its Nu.Q NETs assay. According to Volition, this reflects potential use of the test for improved diagnostic information and ongoing monitoring in NETosis-associated diseases across multiple acute and chronic indications.

How does VolitionRx plan to commercialize its Nu.Q NETs test through the Sysmex partnership?

VolitionRx plans to out-license its Nu.Q NETs test to large companies like Sysmex with global presence. According to Volition, this approach leverages partners' disease expertise, product development capabilities, regulatory experience, and installed analyzers to support future commercialization of the assay.

What benefits could VolitionRx's Nu.Q NETs test offer to patients and clinicians?

VolitionRx believes its Nu.Q NETs test could provide improved diagnostic information to support clinical decision-making and personalized care. According to Volition, the assay is also intended as a low-cost option to continue monitoring a patient's condition in diseases associated with NETosis.