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Verve Therapeutics, Inc. - VERV STOCK NEWS

Welcome to our dedicated page for Verve Therapeutics news (Ticker: VERV), a resource for investors and traders seeking the latest updates and insights on Verve Therapeutics stock.

Verve Therapeutics, Inc. (Nasdaq: VERV) is a cutting-edge biotechnology company headquartered in Cambridge, Massachusetts. With a mission to protect the world from heart disease, Verve is pioneering a transformative approach in cardiovascular care. The company leverages two major breakthroughs in 21st-century biomedicine—human genetics analysis and gene editing—to create life-changing therapies for coronary heart disease.

Verve Therapeutics is focused on developing single-course gene editing medicines to permanently lower LDL cholesterol and triglyceride levels in adults, thereby reducing the risk of coronary heart disease. Their innovative treatments are designed to be administered once in a lifetime, offering a potential shift from chronic disease management to a one-time cure.

Founded by leading experts in cardiovascular medicine, human genetics, and gene editing, Verve has garnered substantial support from top-tier investors, including GV (formerly Google Ventures), Arch Venture Partners, and others. The company was recognized as a '2020 Best Places to Work' by the Boston Business Journal, highlighting its positive workplace culture and innovative environment.

Verve's flagship programs include VERVE-101, VERVE-102, and VERVE-201, each targeting genes validated for their role in lowering low-density lipoprotein cholesterol (LDL-C). Specifically, VERVE-101 and VERVE-102 aim to permanently deactivate the PCSK9 gene, initially targeting patients with heterozygous familial hypercholesterolemia (HeFH) and eventually expanding to treat patients with atherosclerotic cardiovascular disease (ASCVD) who have not reached LDL-C goals using traditional therapies. Meanwhile, VERVE-201 targets the ANGPTL3 gene, focusing on patients with homozygous familial hypercholesterolemia (HoFH) and refractory hypercholesterolemia.

Recent milestones for Verve Therapeutics include the first human proof-of-concept data for in vivo base editing from the ongoing heart-1 phase 1b clinical trial of VERVE-101. This study demonstrated dose-dependent reductions in disease-causing LDL-C in patients with HeFH. The company is also progressing with the heart-2 phase 1b clinical trial for VERVE-102 and plans to launch a phase 1b trial for VERVE-201 in the latter half of 2024.

In terms of financial performance, Verve maintains a solid cash position, with $624.0 million in cash and marketable securities as of December 31, 2023. This robust financial standing is augmented by strategic partnerships, including a significant collaboration with Eli Lilly, which involved a private placement and potential milestone payments up to $465 million.

Under the leadership of CEO Sekar Kathiresan, M.D., Verve is pushing the boundaries of cardiovascular disease treatment. The company's relentless commitment to scientific excellence and patient care positions it as a potential game-changer in the field of genetic medicine.

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Verve Therapeutics (VERV) to Present at J.P. Morgan Healthcare Conference on January 8, 2024
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Verve Therapeutics, Inc. (Nasdaq: VERV) has successfully closed an underwritten public offering of 14,375,000 shares of its common stock at a public offering price of $10.00 per share, resulting in total gross proceeds of approximately $143.8 million. Additionally, the company announced the closing of a private placement of 2,296,317 shares of its common stock to Eli Lilly and Company, at a price per share equal to the public offering price, totaling approximately $23.0 million.
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Verve Therapeutics, Inc. (Nasdaq: VERV) announced the pricing of an underwritten public offering of 12,500,000 shares of its common stock at a public offering price of $10.00 per share, for total gross proceeds of $125.0 million. In addition, Verve has agreed to sell 2,296,317 shares of its common stock to Eli Lilly and Company in a private placement, resulting in aggregate gross proceeds of approximately $148.0 million.
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Verve Therapeutics, Inc. (Nasdaq: VERV) has commenced an underwritten public offering of shares of its common stock and intends to sell up to $35 million of its common stock to Eli Lilly and Company in a private placement. The company also plans to grant the underwriters a 30-day option to purchase additional shares. Jefferies, Guggenheim Securities, William Blair, BMO Capital Markets, and RBC Capital Markets are acting as joint book-running managers for the public offering.
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Verve Therapeutics, Inc.: First human proof-of-concept data for in vivo base editing from the ongoing heart-1 phase 1b clinical trial of VERVE-101 revealed LDL-C reductions of up to 55% and blood PCSK9 protein reductions of up to 84%. The safety profile supports continued development of VERVE-101, with enrollment ongoing in the 0.45 mg/kg and 0.6 mg/kg cohorts and plans to initiate an expansion cohort in 2024.
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Verve Therapeutics, Inc. has made significant progress in developing single-course gene editing medicines for cardiovascular disease, with FDA clearing its Investigational New Drug Application for VERVE-101 in HeFH patients. Verve also announced an expanded collaboration with Eli Lilly and Company and the acquisition of product rights to Verve's PCSK9 and ANGPTL3 programs. The company reported $485.2 million in cash, cash equivalents, and marketable securities, ensuring cash runway into 2026.
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Verve Therapeutics has announced that Eli Lilly and Company (Lilly) has acquired certain product rights to Verve's cardiovascular gene editing programs from Beam Therapeutics. The product candidates are designed to lower low-density lipoprotein cholesterol in patients with or at risk for cardiovascular disease. Lilly now holds the product rights previously held by Beam, including the right to opt-in to share development expenses and to jointly commercialize the products in the United States. Verve retains control of development and commercialization outside the United States.
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Verve Therapeutics receives FDA clearance to conduct clinical trial for cardiovascular disease treatment
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Verve Therapeutics to present interim data from its heart-1 Phase 1b clinical trial of VERVE-101 at AHA Scientific Sessions 2023. VERVE-101 aims to reduce LDL cholesterol. Investor event to be held on November 12, 2023.
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Verve Therapeutics CEO to participate in fireside chat at Cantor Global Healthcare Conference
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FAQ

What is the current stock price of Verve Therapeutics (VERV)?

The current stock price of Verve Therapeutics (VERV) is $5.74 as of December 20, 2024.

What is the market cap of Verve Therapeutics (VERV)?

The market cap of Verve Therapeutics (VERV) is approximately 475.0M.

What is Verve Therapeutics' main focus?

Verve Therapeutics focuses on developing single-course gene editing medicines to treat coronary heart disease by permanently lowering LDL cholesterol and triglyceride levels.

Where is Verve Therapeutics headquartered?

Verve Therapeutics is headquartered in Cambridge, Massachusetts.

What are the key programs of Verve Therapeutics?

The key programs include VERVE-101, VERVE-102, and VERVE-201, targeting genes like PCSK9 and ANGPTL3 to lower LDL cholesterol levels.

Who are some of Verve Therapeutics' investors?

Top-tier investors include GV (formerly Google Ventures), Arch Venture Partners, F-Prime Capital, and others.

What recent milestone has Verve Therapeutics achieved?

Verve announced first human proof-of-concept data for in vivo base editing from the heart-1 phase 1b clinical trial of VERVE-101.

What is the financial condition of Verve Therapeutics?

As of December 31, 2023, Verve Therapeutics has $624.0 million in cash and marketable securities, supporting their operations into late 2026.

What is VERVE-101 designed to do?

VERVE-101 is designed to permanently deactivate the PCSK9 gene in the liver, aiming to reduce LDL cholesterol levels.

Who is the CEO of Verve Therapeutics?

Sekar Kathiresan, M.D., is the CEO of Verve Therapeutics.

What is the significance of Verve's collaboration with Eli Lilly?

The collaboration includes a private placement and potential milestone payments up to $465 million, boosting Verve's financial and development capabilities.

What recognition has Verve Therapeutics received?

Verve was recognized as a '2020 Best Places to Work' by the Boston Business Journal.

Verve Therapeutics, Inc.

Nasdaq:VERV

VERV Rankings

VERV Stock Data

474.96M
80.14M
5.29%
97.82%
20.17%
Biotechnology
Pharmaceutical Preparations
Link
United States of America
BOSTON